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An insider look at the exciting, day-to-day science taking place in the Vendruscolo Lab in @ChemCambridge @Cambridge_Uni 🔬🧪👀
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Vendruscolo Lab retweeted
New research from @mvendruscolo14 @VendruscoloLab & collaborators compares the phase behavior of four α-Synuclein isoforms & finds stark differences between them in their propensities to undergo phase separation & aggregation; #Parkinsons
science.org/doi/10.1126/sc…
science.org/doi/10.1126/sc…
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Vendruscolo Lab retweeted
🔥Very excited to see our work just published in Science Advances! doi.org/10.1126/sciadv… "Transient interactions between the fuzzy coat and the cross-β core of brain-derived Aβ42 filaments". Grateful for the collaboration with @FBrotzakis, @mvendruscolo14, @VendruscoloLab.
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Vendruscolo Lab retweeted
It is always nicer collaborating than competing. In @BiophysJ we join the forces of @PPMC_UAB @VIB_Switch_Lab @VendruscoloLab @UniPadova & @UNI_FIRENZE #Aggregation #Predictors to study #Amyloid #Structure Lead by Fabrizio Chiti
portlandpress.com/biochemj/artic…
portlandpress.com/biochemj/artic…
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Vendruscolo Lab retweeted
🚨Checkout our latest work in @ScienceAdvances on characterising Ab42 Alzheimer's disease brain derived amyloid fibrils structural dynamics using #MEMMI 🖥️ and #CryoEM 🧊data. Work with @MariaMilanesi8 @mvendruscolo14 @VendruscoloLab @Cambridge_Uni @BSRC_Fleming .
🔥Very excited to see our work just published in Science Advances! doi.org/10.1126/sciadv… "Transient interactions between the fuzzy coat and the cross-β core of brain-derived Aβ42 filaments". Grateful for the collaboration with @FBrotzakis, @mvendruscolo14, @VendruscoloLab.
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Vendruscolo Lab retweeted
Grateful for the great turnout at my seminar at @ChemCambridge on chaperones and protein aggregation in neurodegeneration 🧠 It was great to connect, discuss research and explore new collaboration opportunities with so many of you! @KnowlesLabCamb @VendruscoloLab @TWIN2PIPSA
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A touching tribute by @CVR_Research & Colin Robinson honoring the remarkable life and contributions of Professor Sir Christopher M. Dobson, F.R.S.
A visionary scientist and outstanding mentor:
royalsocietypublishing.org/doi/pdf/10.109…
A visionary scientist and outstanding mentor:
royalsocietypublishing.org/doi/pdf/10.109…
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Vendruscolo Lab retweeted
#ML4NGPtalks🎙️
How can #COSTactions like #ML4NGP drive #research and #innovation?
Find out in our first talk with @mvendruscolo14 as he dives into the future of #MachineLearning in #proteinscience.
Watch now!
🎬 youtu.be/ALhG6U6M3vg
@COSTprogramme @VendruscoloLab
How can #COSTactions like #ML4NGP drive #research and #innovation?
Find out in our first talk with @mvendruscolo14 as he dives into the future of #MachineLearning in #proteinscience.
Watch now!
🎬 youtu.be/ALhG6U6M3vg
@COSTprogramme @VendruscoloLab
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Vendruscolo Lab retweeted
Just on my way back from Lisbon from the @TWIN2PIPSA workshop on Bioimaging and Protein Interaction. Thanks @ClaudioGomesLab and @VendruscoloLab for inviting me to present our work on alpha-synuclein phase separation in cells!!
#LLPS #synuclein #science #Parkinson
#LLPS #synuclein #science #Parkinson
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Vendruscolo Lab retweeted
Our latest paper by @Catherine_k_xu
- secondary nucleation is the source of both oligomers and fibrils in Parkinson's associated a-Synuclein aggregation. Fantastic collaboration with Linse lab
@SpillantiniLab and @VendruscoloLab
nature.com/articles/s4146…
- secondary nucleation is the source of both oligomers and fibrils in Parkinson's associated a-Synuclein aggregation. Fantastic collaboration with Linse lab
@SpillantiniLab and @VendruscoloLab
nature.com/articles/s4146…
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Vendruscolo Lab retweeted
Very excited to share our work in @NatureComms! We show that a-synuclein oligomers and fibrils form by secondary nucleation on existing fibril surfaces nature.com/articles/s4146…
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Vendruscolo Lab retweeted
Check out the latest episode (no.9) of the Phase Space Invaders podcast 🎙️ where Prof. Michele Vendruscolo talks about preventing protein misfolding, AI in drug discovery 💊 and the importance of good mentorship 🧠
Access all episodes ➡️ bit.ly/3QO4EBx
@VendruscoloLab
Access all episodes ➡️ bit.ly/3QO4EBx
@VendruscoloLab
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Vendruscolo Lab retweeted
Starting the 2nd day of #ML4NGPmeeting with an inspiring talk from @mvendruscolo14 @VendruscoloLab on #drug design for targeting disordered proteins #IDPs and inhibit #aggregation within condensates 🫧
What an amazing start👏
What an amazing start👏
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Vendruscolo Lab retweeted
The man, the myth, the legend: @StoDada just published a paper with @VendruscoloLab & @ChemCambridge colleagues demonstrating a possible therapeutic route for #Parkinsons based on the inhibition of alpha synuclein protein aggregation within condensates
nature.com/articles/s4146…
nature.com/articles/s4146…
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Vendruscolo Lab retweeted
Outcome of a great collaboration with @VendruscoloLab is now published! Well done @eaandrzejewska.
Super psyched to see this published at last! We demonstrate a novel approach to slowing alpha-synuclein aggregation in #Parkinsons. A massive thank you to the @VendruscoloLab, @KnowlesLabCamb, Caughey, Ghetti and Sormanni labs.
cam.ac.uk/research/news/…
nature.com/articles/s4158…
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Vendruscolo Lab retweeted
🎯Excited to share a new article about our #Twin4Promis partner, @mvendruscolo14 and his incredible team @VendruscoloLab from the @ChemCambridge ! 🌟
Learn more about their pioneering work in protein folding here: rb.gy/s2z0r1
Learn more about their pioneering work in protein folding here: rb.gy/s2z0r1
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Vendruscolo Lab retweeted
Press summary associated with this research: cam.ac.uk/research/news/…
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Vendruscolo Lab retweeted
New research from @robertihorne @KnowlesLabCamb @VendruscoloLab & colleagues presents a machine learning approach to identify small molecule inhibitors of α-synuclein aggregation, a process implicated in #Parkinsons & other synucleinopathies
nature.com/articles/s4158…
nature.com/articles/s4158…
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Vendruscolo Lab retweeted
Now add #AI and structure-based drug discovery for screening 10X faster, 100X more potent , 1000X less cost for new potential small molecule drugs vs #Parkinson's disease
nature.com/articles/s4158…
@robertihorne @Cambridge_Uni @KnowlesLabCamb @VendruscoloLab
nature.com/articles/s4158…
@robertihorne @Cambridge_Uni @KnowlesLabCamb @VendruscoloLab
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Vendruscolo Lab retweeted
Super psyched to see this published at last! We demonstrate a novel approach to slowing alpha-synuclein aggregation in #Parkinsons. A massive thank you to the @VendruscoloLab, @KnowlesLabCamb, Caughey, Ghetti and Sormanni labs.
cam.ac.uk/research/news/…
nature.com/articles/s4158…
cam.ac.uk/research/news/…
nature.com/articles/s4158…
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