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Food insecurity can have long term impacts! Wan Chen Lin leads our new paper showing effects of developmental feeding history in mice on learning, decision making, and dopamine neurons in adulthood. authors.elsevier.com/sd/article/S09… Collab with @BateupLab, Lammel Lab, @christineliuart
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L Wilbrecht retweeted
How does the brain track how much sleep has occurred, and gauge the likelihood of waking at each moment? Check out our new preprint: “A molecular integrator of sleep duration and interruption” biorxiv.org/content/10.648… (1/10)
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L Wilbrecht retweeted
How is decision-making during #adolescence unique?🧠Examine the brain science behind decision-making, learn in what contexts adolescents are more likely to make risky decisions, and explore how to support healthy decisions in a new STEPS Science Spotlight: developingadolescent.semel.ucla.edu/steps-for-yout…
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L Wilbrecht retweeted
DREADDs in humans--update:
3 clinical trials using hM4Di in humans registered in China. 2 for epilepsy and 1 for Parkinson's Disease.
In our original paper we stated:
"...We suggest that at least one of these designer receptors, hM4D, will prove useful for neuronal silencing in seems we were correct.
3 clinical trials using hM4Di in humans registered in China. 2 for epilepsy and 1 for Parkinson's Disease.
In our original paper we stated:
"...We suggest that at least one of these designer receptors, hM4D, will prove useful for neuronal silencing in seems we were correct.
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L Wilbrecht retweeted
The Digital Technology During #Adolescence webinar is ONE WEEK away! Join the CDA + @TheSpringPoint on May 19 at 10:00 am PT for a webinar with Candice Odgers about the impacts of digital technology on young people.
Register now: us02web.zoom.us/meeting/regist…
Register now: us02web.zoom.us/meeting/regist…
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L Wilbrecht retweeted
Where, exactly, does learning happen in the brain?
Out now @Nature , we identify a synaptic locus of birdsong learning and show that the circuit can be tuned to make birds learn faster, but at a cost.🧵 #neuroscience
nature.com/articles/s4158…
Open link: rdcu.be/fiyrS
Out now @Nature , we identify a synaptic locus of birdsong learning and show that the circuit can be tuned to make birds learn faster, but at a cost.🧵 #neuroscience
nature.com/articles/s4158…
Open link: rdcu.be/fiyrS
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L Wilbrecht retweeted
In a new STEPS Science Spotlight, we explain the consequences of food insecurity during #adolescence, and offer ways to use scientific insights to help ensure that adolescents get the reliable nutrition their developing brains and bodies need.
Read more: developingadolescent.semel.ucla.edu/steps-for-yout…
Read more: developingadolescent.semel.ucla.edu/steps-for-yout…
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L Wilbrecht retweeted
One Mind is thrilled to announce the recipients of the 2025 One Mind Rising Star Awards! 💫
⭐️ Laura A. Berner, PhD - Advancing Brain-Based Treatments for Bulimia Nervosa
⭐️ Neir Eshel, MD, PhD - Uncovering How Brain Circuits Drive Motivation
⭐️ Annegret Falkner, PhD - d Therapies for Mood Disorders
⭐️ Andrew Moses Lee, MD, PhD - Neuromodulation to Treat OCD
⭐️ Ed Twomey, PhD - Investigating a Novel Target to Treat Psychiatric Disorders
Made possible by the generous support of our donors—Burroughs Wellcome Fund (@BWFUND), Bristol Myers Squibb (@bmsnews), One Mind's Board of Directors, and another generous donor who wishes to remain anonymous—this year we’re pleased to present five awards! In addition to a $300,000 research grant over 3 years, recipients will receive leadership training through the One Mind Rising Star Leadership Program.
Awardees will present their research on Sept. 13 at the Science & Innovation Symposium, presented by Kaiser Permanente (@aboutKP), to kickoff the 31st One Mind Music Festival. The 2025 festival, presented by @BankofAmerica & Bristol Myers Squibb, will feature a concert performance by @train, presented by @JaMCellars. For tickets visits music-festival.org.
📢 Read the full press release to learn more: bit.ly/2025OMRSA
⭐️ Laura A. Berner, PhD - Advancing Brain-Based Treatments for Bulimia Nervosa
⭐️ Neir Eshel, MD, PhD - Uncovering How Brain Circuits Drive Motivation
⭐️ Annegret Falkner, PhD - d Therapies for Mood Disorders
⭐️ Andrew Moses Lee, MD, PhD - Neuromodulation to Treat OCD
⭐️ Ed Twomey, PhD - Investigating a Novel Target to Treat Psychiatric Disorders
Made possible by the generous support of our donors—Burroughs Wellcome Fund (@BWFUND), Bristol Myers Squibb (@bmsnews), One Mind's Board of Directors, and another generous donor who wishes to remain anonymous—this year we’re pleased to present five awards! In addition to a $300,000 research grant over 3 years, recipients will receive leadership training through the One Mind Rising Star Leadership Program.
Awardees will present their research on Sept. 13 at the Science & Innovation Symposium, presented by Kaiser Permanente (@aboutKP), to kickoff the 31st One Mind Music Festival. The 2025 festival, presented by @BankofAmerica & Bristol Myers Squibb, will feature a concert performance by @train, presented by @JaMCellars. For tickets visits music-festival.org.
📢 Read the full press release to learn more: bit.ly/2025OMRSA
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L Wilbrecht retweeted
Between the ages of 16 and 25, we are motivated to learn, explore, and connect with others in ways that help us transition to the agency & responsibilities of adulthood.
Learn more about this critical stage of development with our new 16 to 25 fact sheet: developingadolescent.semel.ucla.edu/topics/item/16…
Learn more about this critical stage of development with our new 16 to 25 fact sheet: developingadolescent.semel.ucla.edu/topics/item/16…
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L Wilbrecht retweeted
🎉Thrilled that the lab’s first paper is out today in @Nature! Credit to the amazing @cesca_gst, @HernyMV and @YviJohansson. Thank you to everyone involved in this massive effort! nature.com/articles/s4158…
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L Wilbrecht retweeted
New hope for families battling Dravet Syndrome.
Scientists have developed a new gene replacement therapy that could improve treatments for a rare and life-altering form of epilepsy. 🧵
Scientists have developed a new gene replacement therapy that could improve treatments for a rare and life-altering form of epilepsy. 🧵
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L Wilbrecht retweeted
To conclude our February focus on peer relationships, we have compiled research on the importance and impact of #friendships during #adolescence into an applicable fact sheet!
Learn 5 Fast Facts About Peer Relationships and Friendships During Adolescence: developingadolescent.semel.ucla.edu/topics/item/5-…
Learn 5 Fast Facts About Peer Relationships and Friendships During Adolescence: developingadolescent.semel.ucla.edu/topics/item/5-…
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L Wilbrecht retweeted
New study from our lab, in collab with @erlichlab
We developed novel frameworks to study multi-agent decision-making in mice.
Mice flexibly shift their value preference under social competition, by integrating real-time self and opponent information!
biorxiv.org/content/10.110…
We developed novel frameworks to study multi-agent decision-making in mice.
Mice flexibly shift their value preference under social competition, by integrating real-time self and opponent information!
biorxiv.org/content/10.110…
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L Wilbrecht retweeted
Delighted to share this new work from the lab. A tour-de-force from @casklune @cgoodpaster3 and @michaelgongwer showing how the maturation of frontolimbic circuits underlies developmental milestones in threat avoidance behaviors.
Multiple developmental switches in mPFC-NAc and mPFC-BLA pathways that underlie developmental transitions in threat avoidance behavior revealed by circuit dissection in juvenile, adolescent and adult mice mice
@ladenardo @casklune @cgoodpaster3
nature.com/articles/s4159…
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L Wilbrecht retweeted
A new resource from the National Scientific Council on #Adolescence outlines how adults can support adolescents during and after the #2024Election.
Learn how elections can be opportunities to support positive #adolescent development: developingadolescent.semel.ucla.edu/topics/item/el…
Learn how elections can be opportunities to support positive #adolescent development: developingadolescent.semel.ucla.edu/topics/item/el…
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L Wilbrecht retweeted
Excited to share our review with our MDPhD student Sam Allen @SinaiBrain just out in @ScienceAdvances
"Local and Long-range input Balance: A framework for investigating frontal cognitive circuit maturation in health and disease"
science.org/doi/10.1126/sc…
"Local and Long-range input Balance: A framework for investigating frontal cognitive circuit maturation in health and disease"
science.org/doi/10.1126/sc…
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L Wilbrecht retweeted
🍭CANDY Lab is hiring a post-bac RA! 🧠
We’re launching a study on puberty effects on brain dev in teens with autism. 🧩
Perfect for recent or soon to be grads who are passionate about autism research and looking to prepare for PhD programs
Apply here👉 tiny.cc/6sz7zz
We’re launching a study on puberty effects on brain dev in teens with autism. 🧩
Perfect for recent or soon to be grads who are passionate about autism research and looking to prepare for PhD programs
Apply here👉 tiny.cc/6sz7zz
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Juliet Davidow @learning_brain and I spent some time thinking about adolescent strengths and circuits that support adolescent skill learning, long term goal formation, even possibly a sense of purpose. What drives adolescents to explore and where do they store what they learn?
Goal-directed learning in adolescence: neurocognitive development and contextual influences — a Review by Linda Wilbrecht & Juliet Y. Davidow
go.nature.com/48LA9mw
@WilbrechtL @learning_brain
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It’s thought provoking to stop and think what is adolescence for? and where do adolescents excel? What have we needed to learn to transition to independence and then adulthood in our communities? How does our biology support this transition?
Most animals fly the nest soon after puberty, without the prolonged adolescence that we humans have. Recent research looking at teenage brains has revealed a hidden evolutionary advantage. newscientist.com/article/mg2613…
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L Wilbrecht retweeted
Research shows that the willingness to approach the new and unknown during #adolescence is an important quality that helps us adapt to the world and prepare for adulthood. 💯
To learn more, check out our website: developingadolescent.semel.ucla.edu/topics/item/5-…
To learn more, check out our website: developingadolescent.semel.ucla.edu/topics/item/5-…
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L Wilbrecht retweeted
Did you know that #youth with a greater sense of purpose are happier, healthier, and more motivated to achieve a wide range of positive developmental outcomes? Learn more in a new council report written by the National Scientific Council on Adolescence: developingadolescent.semel.ucla.edu/topics/item/pu…
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