When it comes to modulating cereblon for TPD, the future is allostery 🫡. Read more about this intersection of allosteric modulation and target protein degradation in our latest review by Vanessa 🥂, out now in @ACSCentSci! 💙 #thefutureisallostery
doi.org/10.1021/acscen…

We posted a preprint on all-to-all functional mapping of a cortical microcircuit in vivo. biorxiv.org/content/10.648…
Yitong Qi developed molecular tools, optics, and protocols for massively parallel optogenetic stimulation and voltage imaging during animal behavior.

In the 1950s, Lipscomb & colleagues unpicked the structures of several boranes using low-temperature x-ray crystallography, determining they shared two electrons across three atoms.

This accounted for boranes’ unusual geometry & unexpected dipole moment.
chemistryworld.com/news/fifty-yea…

🎉Congrats to Megan @Meghan_Sulliva, Jesse @Jesse_Gordon9 & Brandon from Nocera Group
@HarvardCCB 🔬onlinelibrary.wiley.com/doi/10.1002/an…
@angew_chem #crystallography #SpaceGroupChoice #Education

Thank you @Harvard for featuring our fitness landscape design (FLD) work in "How to build an evolutionary trap for viruses"!

Read the article in the FAS current below: current.fas.harvard.edu/stories/how-bu…

We wrote a tutorial guide on voltage imaging, now out in Neuron: authors.elsevier.com/a/1nlgh3BtfHGp…. Indicators, microscopes, and software have all advanced to the point that it's not so hard -- you can now directly watch the electrical activity of neurons in live animals or in culture.

New #research: How your cells make a molecule you can buy as a supplement, CoQ10 current.fas.harvard.edu/stories/how-yo… #chemtwitter

🎉Congrats to Nick @BetleyGroup @HarvardCCB 🔬Hydrogenation of a Tricobalt Carbide Evolves through Fischer–Tropsch Intermediates 😀
pubs.acs.org/jacsat/article… @J_A_C_S #crystallography #Education

Congratulations to @brian_b_liau on winning the 2027 Tetrahedron Young Investigator Award For Bioorganic and Medicinal Chemistry! #chemtwitter sciencedirect.com/journal/tetrah…

Competing species/strains lead to noisy, complex evolutionary trajectories. It's difficult to extract genotype fitnesses from experimental time series or population-level sequencing data.

Until now! All you need is 1 equation:
doi.org/10.64898/2026.…

Useful for experiments!
1/N

RT @OnoInitiative: The 2026 Ono Initiative Award is presented to @BalskusLab, @brian_belardi, @AChemSynBio as noted. Congratulations!
Emily…

@HarvardCCB is pleased to announce that leading chemist Jeffrey R. Long (Holm Lab alumnus) will be joining our department as the inaugural Thomas C. Foley Professor of Energy and the Environment: current.fas.harvard.edu/stories/leadin… #chemtwitter

I’m thrilled to announce Fitness Landscape Design (FLD), the first protocols for reshaping protein evolution to fight disease! FLD can proactively suppress viral fitness trajectories before mutations even arise. @Harvard @MIT

Today in PNAS: pnas.org/doi/10.1073/pn…

MORE SOON!

How can microbes🦠 evolve drug 💊resistance without weakening drug binding?

And how do chaperones decide which proteins to recognize? (1/n)

NEW: Professor Xiaowei Zhuang has been awarded the 2026 Dickson Prize in Medicine, @pitt_medicine's highest honor: medschool.pitt.edu/news/xiaowei-z…

For #ChemistsCelebrateEarthWeek, we're spotlighting the 2021 winner of the Dreyfus Prize conferred in Environmental Chemistry, James Anderson (@Harvard): youtube.com/watch?v=s_u-H4…

Pour a glass of champagne AND red Bordeaux—Our newest work with @GSK and @scrippsresearch is out in @Nature, where we describe SB-405483, the first allosteric CRBN ligand which potentiates neosubstrate degradation. Congrats Vanessa and all authors! 🍷💫💐
nature.com/articles/s4158…

Our study on discovering cooperative catalysis is in print @Nature! With @JacobsenLab @eugene_e_kwan @Merck @RichrdLiu we use simple math-based pooling/deconvolution to uncover useful catalyst combinations with minimal experiments

Read for free! rdcu.be/eN5i5

🎉Congrats to Jeewhan @BetleyGroup @HarvardCCB 🔬In the ferrous state, (EmL)Fe(OH) shows nucleophilic reactivity toward carbon-based electrophiles, including reversible #CO2capture characterized by #SCXRD 😀doi.org/10.1021/jacs.5… @J_A_C_S #crystallography #education

The 2026 #ErnestSolvayPrize goes to Prof. Xiaowei Zhuang from Harvard University and Howard Hughes Medical Institute.

Her pioneering work in advanced cellular imaging lets scientists map and visualize the inner organization of cells and tissues at the molecular level, revealing o a change and where this response takes place.

This is science that pushes boundaries and helps build a more sustainable, connected and human future.

👉 Discover more: bit.ly/3Nnlrwm

#Syensqo #SyensqoFund