Amazing to have been a part of this wonderful team. Congrats to everyone on the study! Special shoutout to @AManbachi and Nick Theodore for your team leadership, and @DARPA for supporting the work!

@JHUBME @TTECJHU @HopkinsEngineer @HopkinsMedicine @JohnsHopkins @HopkinsNeuro

In a mouse model of #colitis, researchers show how gut immune cells sense colonic stiffening, and how that signal can lead to nerve remodeling that causes visceral pain.

Learn more in Science #Immunology: scim.ag/4dSrFPb

Don’t forget! Society for Biomaterials 2027 (Seattle) abstracts are due soon (by November 3rd)!

@SFBImmuneEng @Abhi_Immuneng @DrMTeplensky @AliasgerSalem

@JohnsHopkins @HopkinsEngineer @JHUBME @TTECJHU @JHU_ChemBE @JHUMaterials @INBT_JHU

T cell immunity declines with thymic atrophy, but thymic cell grafts rescue T cell function go.nature.com/3Jp6B72
rdcu.be/4C6R4B1ZJaWa

The @JohnsHopkins BME undergraduate program is once again ranked No. 1 in the nation by @usnews. Students dive into hands-on research from day one, helping drive innovation in human health.

Read more: bme.jhu.edu/news-events/ne…

Proud of our @nyulangone Dean (and prior @Perlmutter_CC Director) Alec Kimmelman for his @Nature paper today:

Hepatocytes promote liver metastasis of #PancreaticCancer by providing serine
nature.com/articles/s4158…
With @BarDafna @RichPossemato @KoelinaG @nyugrossman

Cancer patients waste away partly because their own fat starts burning itself. The signal that starts it is not a cytokine. It is iron. Could this insight lead to a drug to prevent cachexia in cancer patients?

doi.org/10.1038/s43018…

An experimental blood test detected 87% of early-stage pancreatic ductal cancers in an international study.

Plasticity of the infant immune system during the perinatal period dlvr.it/TVXqvS

Macrophages eating living cells...NATURE paper !

nature.com/articles/s4158…

Pain producing neurons around #cancer generate immune suppressive molecules...

The neuroimmunology of cancer is crazy...and its an area that is highly overlooked....

nature.com/articles/s4158…

We’re hiring! Join the Hickey Lab at Duke as a full-time Research Assistant developing reproducible agent-based models of human tissues. We seek experience in Python, computational modeling, and biology. 1–2 years, Durham, NC. Apply/share: forms.gle/Abfbwb4B8a8Wyc…

Excited to share our new review in @CellCellPress. We propose fibrosis is a reversible state encoded in chromatin circuits shaped by immune-stromal crosstalk, and that rewiring this logic may offer durable therapeutic paths. @GladstoneInst

authors.elsevier.com/sd/article/S00…

Engineering our immune cells has successfully treated many types of cancer and even led to cure of some autoimmune diseases. But the engineering of cells was done outside the body, is highly complex, takes 3 to 6 weeks, and is not scalable.
But now there are many in vivo (inside cal trials reading out soon. Watch this space. nature.com/articles/d4157…

The longest lived people among us, called "supercentenarians," have an abundance of cancer-killing immune cells, study finds.

Learn more in Cell Reports: cell.com/cell-reports/f…

Kosuke Hashimoto, Nobuyoshi Hirose, Piero Carninci, Yasumichi Arai, & colleagues
@CellReports

Using single-cell immune profiling, scientists from the University of Osaka analyzed T cells from #supercentenarians and found that cytotoxic T lymphocytes begin to expand around the age of 100, characterized by sequential CD27/CD28 loss without exhaustion. bit.ly/4y8im5t

📖: @CellReports

Huge faculty recruitment effort at the University of Chicago -- a division-wide, open-rank search looking to hire about 20 faculty across 5 research areas in biology. Come be our colleague!

Full announcement: uchicago.app.box.com/s/ckih9zv3rjlj…

#Bcells favor different #memory fates in response to barrier tissue infections, forming plasma cells in the gut and memory B cells in the lungs in mice.

Learn more in Science #Immunology: scim.ag/4wae4tK

Happy to share a recent publication with our collaborators at Wilmer on crystalline drug delivery to the eye to treat wet age-related macular degeneration @JCRnEDITORS!
sciencedirect.com/science/articl…

& Recent press release:
bme.jhu.edu/news-events/ne…

@JHUBME @TTECJHU @HopkinsMedicine