Pinned Tweet
Excited to share our work on chromatin landscape remodeling in cloned embryos! ššWe started off w/ simple question: how does the somatic epigenome reprogram to prepare for the onset of transcription (EGA)? tinyurl.com/yc4wv76p
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Edward Grow, PhD retweeted
Interested in applying to Stanford Genetics PhD program? Join this informational zoom meeting with our department chair (Lars Steinmetz) and current Genetics grad students:
When: Thursday November 5
Time: 11 am-12 pm pacific time
Zoom link: stanford.zoom.us/j/98116204859?ā¦
Password: 535381
When: Thursday November 5
Time: 11 am-12 pm pacific time
Zoom link: stanford.zoom.us/j/98116204859?ā¦
Password: 535381
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Edward Grow, PhD retweeted
Heartbroken to hear of Marta Shahbaziās passingā¦
I first met Marta in 2017 while visiting Magdalena Zernicka-Goetzās lab, before many of her landmark Nature and Nature Cell Biology papers appeared. She was smart, warm, and passionate about science. I knew she would become a star, and she did.
Just before COVID, amid the transition to her own independent lab, Marta generously prepared primed and naĆÆve human embryonic stem cells at Magdaās Cambridge lab for our PANDORA-seq project. We coauthored the paper in 2021, and I will always remember her kindness and willingness to help during such a busy time.
The world has lost a wonderful scientist and a good person. My deepest condolences to her family and everyone who loved her. May you rest in peaceā¦
bbc.com/news/articles/ā¦
I first met Marta in 2017 while visiting Magdalena Zernicka-Goetzās lab, before many of her landmark Nature and Nature Cell Biology papers appeared. She was smart, warm, and passionate about science. I knew she would become a star, and she did.
Just before COVID, amid the transition to her own independent lab, Marta generously prepared primed and naĆÆve human embryonic stem cells at Magdaās Cambridge lab for our PANDORA-seq project. We coauthored the paper in 2021, and I will always remember her kindness and willingness to help during such a busy time.
The world has lost a wonderful scientist and a good person. My deepest condolences to her family and everyone who loved her. May you rest in peaceā¦
bbc.com/news/articles/ā¦
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Edward Grow, PhD retweeted
Happy to see our work on Polycomb repression establishment in human embryos is now out! Heroic efforts from Xiaoyu Hu, Chuanxin Zhang and their fellows Bofeng Liu, Fangnong Lai and Shuiying Ma. Terrific collaboration w/ Zijiang Chen and her team! nature.com/articles/s4158ā¦
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Edward Grow, PhD retweeted
Interested in exploring the molecular mechanisms of early mammalian development?
Fully funded 4-year PhD opportunity at the University of Dundee!
We are seeking a motivated PhD student to lead a biochemical and structural biology project.
See the link
findaphd.com/phds/project/eā¦
Fully funded 4-year PhD opportunity at the University of Dundee!
We are seeking a motivated PhD student to lead a biochemical and structural biology project.
See the link
findaphd.com/phds/project/eā¦
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Edward Grow, PhD retweeted
šŖRegeneration is a conversation between stem cells and their surroundings. š„³Iām excited to share our new review on the expanding landscape of stem cell niches and how understanding stem cellāniche dialogue could advance tissue repair and healthy aging šŖš½
sciencedirect.com/science/articlā¦
sciencedirect.com/science/articlā¦
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Edward Grow, PhD retweeted
When you look at the teamwork behind work like what was just published here, you realize the coordination required across teams, datasets, and time.
Will AI help us with this coordination? What if we took the same dataset and findings here... and asked AI to coordinate the data, find overlooked relationships, and uncover additional insights? What happens when you add to this the work of thousands of other papers in the space? Mere mortals cannot encompass the range of expertise required to fully plumb the opportunities.
That's an AI/SI goal worth pondering. But what resources would it take to make it happen?
Congratulations to Patel et al., the other authors, and the rest of the team without whose effort a work of this complexity could not come to the aid of patients with dire diseases such as those represented in this publication. And, of course, thanks to the patients and family members whose lives are represented in papers like this.
Will AI help us with this coordination? What if we took the same dataset and findings here... and asked AI to coordinate the data, find overlooked relationships, and uncover additional insights? What happens when you add to this the work of thousands of other papers in the space? Mere mortals cannot encompass the range of expertise required to fully plumb the opportunities.
That's an AI/SI goal worth pondering. But what resources would it take to make it happen?
Congratulations to Patel et al., the other authors, and the rest of the team without whose effort a work of this complexity could not come to the aid of patients with dire diseases such as those represented in this publication. And, of course, thanks to the patients and family members whose lives are represented in papers like this.
SCI member @GarryPNolan & others map cellular states across 54 #neuroblastoma tumors, uncovering ADRN and MES tumor cells. Crucially, high MES gene expression predicts worse survival, independent of clinical risk factors. brnw.ch/21x6p9L
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Edward Grow, PhD retweeted
Our Nature Medicine paper is out: menopause isn't a slow slope. Across 300M+ lab tests from 1M+ women, many body systems jump at the final menstrual period. Men show no such jump. 1/4
nature.com/articles/s4159ā¦
nature.com/articles/s4159ā¦
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Edward Grow, PhD retweeted
Are weak TF motifs important? @ZeitlingerLab use deep learning to systematically map low-affinity pioneer binding sites in mESCs and show that they cooperate with strong motifs to open chromatin. Preview w/ @gracecbower: cell.com/cell-genomics/ā¦ Paper: cell.com/cell-genomics/ā¦
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Edward Grow, PhD retweeted
Donāt take it from me, but a huge regulator for female health beyond reproduction is the ovary.
Decoding its biology is some of the most valuable work one could en doing and funding today.
Decoding its biology is some of the most valuable work one could en doing and funding today.
By the time most women turn 50, the ovaries are down to so few eggs leading to menopause & many scientists to lose interest. Researchers analyzed 28 ovaries from women between 50-75. Many of the 6,000 proteins measured stayed consistent across the years.
washingtonpost.com/health/2026/10ā¦
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Edward Grow, PhD retweeted
We're hiring too! š§ š§¬ Two PhD projects in our lab: glioblastoma as a cellular ecosystem, and neurodevelopmental disorders modeled with patient iPSCs and organoids. Apply by 19 Oct!
dkfz.de/en/cell-fate-eā¦
dkfz.de/en/cell-fate-eā¦
Dreaming of a career in cancer research? Join the International PhD Program at @DKFZ . Explore #cancerresearch including #cancerbiology, #bioinformatics, #epidemiology & #medicalphysics. The Winter Selection is open now š apply t1p.de/hl56b
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Edward Grow, PhD retweeted
Cervical clues: Olfm4 as a marker of epithelial diversity and plasticity
This Research Highlight showcases work by Mala Mahendroo, Shanmugapriyaa Madhukaran and colleagues.
journals.biologists.com/dev/article/15ā¦
This Research Highlight showcases work by Mala Mahendroo, Shanmugapriyaa Madhukaran and colleagues.
journals.biologists.com/dev/article/15ā¦
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Edward Grow, PhD retweeted
New preprint with @ZernickaGoetz on lineage reconstruction in mouse embryos and stem cell-derived embryo models, led by Yunzheng Liu (@Rachsuliusy )! (1/13) doi.org/10.64898/2026.ā¦
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Edward Grow, PhD retweeted
The only way to combat the AI cheating crisis is with intensive instruction. This requires smaller class sizes and profs who arenāt teaching 5 courses a semester at 4 different colleges like many adjuncts. Cut the make-work admins, do a TT-hiring blitz. Anything else is madness.
Today I take the highly controversial position that in fact 4 year universities are supposed to be about education, not football, sex, drinking, or hiring lots of administrators, and they've lost the plot.
dilanesper.substack.com/p/colleges-areā¦
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Edward Grow, PhD retweeted
Female reproductive lifespan depends mostly on biological signalling, not the number of eggs remaining.
nature.com/articles/s4358ā¦
nature.com/articles/s4358ā¦
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Edward Grow, PhD retweeted
1. CRISPR came from basic research on bacteria.
2. Optogenetics started with a discovery in algae.
3. The GFP protein comes from jellyfish.
The biggest breakthroughs all trace to scientists follow their curiosity. This is one huge reason why we must keep funding basic research!
2. Optogenetics started with a discovery in algae.
3. The GFP protein comes from jellyfish.
The biggest breakthroughs all trace to scientists follow their curiosity. This is one huge reason why we must keep funding basic research!
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Edward Grow, PhD retweeted
who are still writing research papers completely manually? am I the only person who thinks this is the only way of staying human and genuine ?
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Did not have a āanyone can have a valid opinion about gene editing human embryos despite not having the technical ability to accomplish said experimental procedure or conceptual framework to be able to sufficiently analyze a safety profileā on my 2026 bingo card. š¤¦āāļø
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Edward Grow, PhD retweeted
genuinely in awe of how the tech fiefdoms sent all their best hype men to try to court the Holy See and the response was Leo staking his entire pontificate on waging a crusade against AI
Intelligence must draw on memory. The mind must not simply compile data ā as an algorithm now does more quickly than we can ā but recall lived experiences, which contain depths of meaning that only the human soul can recognize, and connect more deeply with the goodness of these experiences. Everything that is good begins āwith the Spiritā and thus possesses a breath, a dynamism and a sense of communion that, once experienced, are engraved upon the heart. vatican.va/content/leo-xiā¦
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Edward Grow, PhD retweeted
Huge Congratulations to Azim Surani on his retirement. He discovered genomic imprinting-a foundation of epigenetics. Later: germ cell specification & reprogramming. Azimās rigorous scholarship, humble kindness, and insights were so inspiring.@GurdonInstitute @Cambridge_Uni
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Edward Grow, PhD retweeted
We are looking to welcome new Tenure Track assistant/associate professors to our research community for the fifth time in HiLIFEās history š
Submit your application by November 16, and spread the word within your networks too!
tinyurl.com/3fdt78ry
#lifescience #recruitment
Submit your application by November 16, and spread the word within your networks too!
tinyurl.com/3fdt78ry
#lifescience #recruitment
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