Are you doing research in Denmark and looking for postdoctoral opportunities?
Have a look at this call from the Novo Nordisk Foundation:
novonordiskfonden.dk/grant/postdoct…
contact me if you are interested in applying.
Have a look at this call from the Novo Nordisk Foundation:
novonordiskfonden.dk/grant/postdoct…
contact me if you are interested in applying.
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CarlssonLab retweeted
Bridging NMR and molecular simulations to uncover hidden GPCR dynamics!
Our new study introduces GPCRmd-NMR, combining ML-based NMR predictors and MD simulations to support NMR experiments and reveal GPCR states beyond crystallography.
🔗 doi.org/10.1038/s41594…
#GPCR #NMR
Our new study introduces GPCRmd-NMR, combining ML-based NMR predictors and MD simulations to support NMR experiments and reveal GPCR states beyond crystallography.
🔗 doi.org/10.1038/s41594…
#GPCR #NMR
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Hiring a postdoctoral researcher with expertise in structure-based ligand design, with focus on peptide-binding GPCRs.
uu.varbi.com/en/what:job/jo…
uu.varbi.com/en/what:job/jo…
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CarlssonLab retweeted
📢 GPCR Forum is back after Summer break ☀️
As the first Zoominar after the break, we are hosting @NourKahlous from @CarlssonLab at @uppsalauni on the 27th of August, 4 pm CET.
As always, send a DM to receive the JOIN link or check the @GPCRForum mailing list.
As the first Zoominar after the break, we are hosting @NourKahlous from @CarlssonLab at @uppsalauni on the 27th of August, 4 pm CET.
As always, send a DM to receive the JOIN link or check the @GPCRForum mailing list.
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CarlssonLab retweeted
We present a structure-based strategy for discovering small molecules targeting peptide-activated receptors.
Applied to neurotensin receptors #GPCRs, it yielded anti-pain compounds rdcu.be/fwQ0Z
To enable broader application of the strategy, we provide access to...1/x
Applied to neurotensin receptors #GPCRs, it yielded anti-pain compounds rdcu.be/fwQ0Z
To enable broader application of the strategy, we provide access to...1/x
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Read our paper on structure-based design of small-molecule agonists of neurotensin receptors with in vivo analgesic activity: nature.com/articles/s4146…
@NatureComms
@uppsalauni
@scilifelab
@ERC_Research
@NatureComms
@uppsalauni
@scilifelab
@ERC_Research
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CarlssonLab retweeted
Very cool paper!
Docking of virtual libraries identifies small-molecule agonists of neurotensin receptors with analgesic activity
nature.com/articles/s4146…
Docking of virtual libraries identifies small-molecule agonists of neurotensin receptors with analgesic activity
nature.com/articles/s4146…
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CarlssonLab retweeted
Recent advances in #peptide-GPCR interactions are transforming drug discovery. This #Primer details experimental and computational approaches, from in silico peptide mining to modern biosensor assays, paving the way for novel therapeutics.
nature.com/articles/s4358…
nature.com/articles/s4358…
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Interested in peptide-binding G protein-coupled receptors (GPCRs)?
Have a look at: “Peptide ligand discovery of G protein-coupled receptors”, in Nature Reviews Methods Primers:
nature.com/articles/s4358…
Have a look at: “Peptide ligand discovery of G protein-coupled receptors”, in Nature Reviews Methods Primers:
nature.com/articles/s4358…
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CarlssonLab retweeted
Improving AlphaFold2 Performance in Virtual Screens Targeting GPCRs by Enhancing Binding-Site Conformational Sampling #AlphaFold
pubs.acs.org/doi/10.1021/ac…
#JCIM Vol66 Issue10 #compchem
pubs.acs.org/doi/10.1021/ac…
#JCIM Vol66 Issue10 #compchem
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Happy to have contributed to this cool paper from the Pål Stenmark group on the molecular mechanisms of DNA-repair by SMUG1. nature.com/articles/s4146…
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CarlssonLab retweeted
Great use of comparative genomics to engineer receptors! Stay tuned for our upcoming publication (fingers crossed) investing similar evolutionary hotspots for all human GPCR families.
Read our just published paper on the molecular mechanisms of native ligand selectivity in G protein-coupled receptors: nature.com/articles/s4146…
@NatureComms
@UU_University
@scilifelab
@KAW
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CarlssonLab retweeted
Article: Molecular mechanisms of native ligand selectivity in catecholamine G protein-coupled receptors
#research supported by Knut and Alice Wallenberg Foundation
#biology #science @NatureComms
tinyurl.com/3a98zyhc
#research supported by Knut and Alice Wallenberg Foundation
#biology #science @NatureComms
tinyurl.com/3a98zyhc
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