Pinned Tweet
So happy to finally see our paper published! 🥂
If you're interested in plasmid biology, check it out! 👀🧬
If you're interested in plasmid biology, check it out! 👀🧬
🚨🚨New paper out!!!
Come for the first large-scale analysis of plasmid copy number across species,
stay for one of the most intriguing results of my lab: universal scaling laws in plasmid biology! 📈🧬
👉nature.com/articles/s4146…
1
7
17
1,654
Paula Ramiro retweeted
Happy to see our paper on how environmental conditions influence the ecological and evolutionary dynamics of antibiotic resistance in @AnnualReviews
Ecological Kinetics and Evolutionary Dynamics of Antibiotic Resistance in Complex Environments - go.shr.lc/4yMFohZ
Ecological Kinetics and Evolutionary Dynamics of Antibiotic Resistance in Complex Environments - go.shr.lc/4yMFohZ
0
8
22
1,118
Paula Ramiro retweeted
Happy to share that our new preprint is now available on bioRxiv! biorxiv.org/content/10.648…
Our study explores commensal Enterobacterales and the mobile genetic elements associated with antimicrobial and heavy metal resistance @TMcoque @microRyC
Our study explores commensal Enterobacterales and the mobile genetic elements associated with antimicrobial and heavy metal resistance @TMcoque @microRyC
0
3
5
245
Paula Ramiro retweeted
What if multireplicon plasmids are not an oddity, but an evolutionary strategy?
We found that they are common, more mobile, broader-host-range, and enriched in AMR.
Even more interesting: their assembly doesn’t look random. 👀
Preprint: biorxiv.org/content/10.648…
See below!🧵👇
We found that they are common, more mobile, broader-host-range, and enriched in AMR.
Even more interesting: their assembly doesn’t look random. 👀
Preprint: biorxiv.org/content/10.648…
See below!🧵👇
1
2
2
122
Paula Ramiro retweeted
We are pleased to share our last article rdcu.be/fabhM. It offers the most comprehensive analysis so far of Ab+non-Ab resistance genes in human gut microbiome, using an Indigenous population (low industrialization, chronic Hg exposure from gold mining) 6/6👇
2
12
19
1,314
Paula Ramiro retweeted
New #BehindThePaper for our latest paper in @NatureComms (rdcu.be/e2qMK)
Secret Invasion: Strain Fate Across Microbiomes
Cover illustration by Helena Klein (@illuzation_hk).
communities.springernature.com/posts/secret-i…
Secret Invasion: Strain Fate Across Microbiomes
Cover illustration by Helena Klein (@illuzation_hk).
communities.springernature.com/posts/secret-i…
0
1
5
415
We're thrilled that, in addition, our figure has been chosen as the cover for this issue of PNAS! 🥹🎉
New paper out in PNAS!!! 🎉
Do more plasmid copies mean faster evolution?
🧵 Dive into the story
pnas.org/doi/10.1073/pn…
1
1
14
734
New paper out in PNAS!!! 🎉
Do more plasmid copies mean faster evolution?
🧵 Dive into the story
pnas.org/doi/10.1073/pn…
Do more plasmid copies mean faster evolution?
🧵 Dive into the story
pnas.org/doi/10.1073/pn…
3
26
51
4,002
Plasmids are not just gene delivery platforms.
They boost the availability of mutations, enabling rapid evolution of traits like resistance, metabolism, and virulence, highlighting their role as evolutionary powerhouses of bacterial cells.
PCN is key to evolvability 🫧🤩
They boost the availability of mutations, enabling rapid evolution of traits like resistance, metabolism, and virulence, highlighting their role as evolutionary powerhouses of bacterial cells.
PCN is key to evolvability 🫧🤩
1
0
4
110
Huge thanks to all my brilliant co-authors 🙌
@BioNacho,
@Laura_Jaraba_ , Val F. Lanza, Cristina Herencias Rodríguez, Adrián González Casanova,
@penamiller
& Jerónimo Rodríguez-Beltrán
@BioNacho,
@Laura_Jaraba_ , Val F. Lanza, Cristina Herencias Rodríguez, Adrián González Casanova,
@penamiller
& Jerónimo Rodríguez-Beltrán
0
0
7
162
Paula Ramiro retweeted
TWiM explains a study that examines pathogen presence in ancient humans and concludes that zoonoses emerged 6500 years ago with the domestication of livestock, and determination of universal rules that govern plasmid copy number. 📺 bit.ly/47bjew1
1
2
8
1,465
Paula Ramiro retweeted
Habreis visto esta foto de las vacas de mi padre en muchos sitios con diferentes historias y mucha especulación -como en el tuit que cito-. Os cuento como se produjo este milagro en este artículo: elpais.com/espana/madrid/…
La importanciade que lso animales pastoreen y limpien el terreno… la naturaleza y los bomberos ayudaron a este pequeño milagro en el #incendio de los tres cantos #trescantos #incendiotrescantos #Incendioforestal
1
6
10
1,358
Paula Ramiro retweeted
Our latest manuscript is out!
Conjugative plasmids fuel AMR through IS-mediated gene inactivation, promoting the evolution of multidrug resistance in bacteria.
Hope you like it
Conjugative plasmids fuel AMR through IS-mediated gene inactivation, promoting the evolution of multidrug resistance in bacteria.
Hope you like it
New paper out! 📣📣
Plasmids promote antimicrobial resistance through Insertion Sequence-mediated gene inactivation.
Combining experiments and bioinformatics, we unveil how two of the most prevalent bacterial MGE accelerate the evolution of AMR. 🧵👇🏻
biorxiv.org/content/10.110…
0
6
10
683
Paula Ramiro retweeted
A new encyclopedic review, for plasmid lovers:
academic.oup.com/nar/article/53…
We (Mapi, Eduardo and I) hope you like it!
academic.oup.com/nar/article/53…
We (Mapi, Eduardo and I) hope you like it!
0
31
85
6,089
Plasmids aren't just passengers; they're drivers of bacterial evolution 🧬
Mutation rate scales with plasmid copy number, boosting adaptability 💥
Check out our latest preprint! 🚨
biorxiv.org/content/10.110…
Mutation rate scales with plasmid copy number, boosting adaptability 💥
Check out our latest preprint! 🚨
biorxiv.org/content/10.110…
2
21
93
5,938
Paula Ramiro retweeted
Hot off the press and a must-read this summer! Huge congrats to the whole team, especially @paula_micro, for this fantastic work. Don’t miss it! 👇
Plasmids promote bacterial evolution through a copy number-driven increase in mutation rate biorxiv.org/content/10.110… #biorxiv_micrbio
0
3
8
603