Very excited to announce the release of my first solo book:

Talk Python in Production: A Cloud-Agnostic Guide to Building, Scaling, and Managing Your Own #Python Infrastructure

talkpython.fm/books/python-i…

joined @TalkPython w/ @mkennedy, @reuvenmlerner, @calvinhp, and pat decker to talk about "the state of python in 2026"

so much of it came back to development w/ agents! harnesses, observability, and why ~90% of my coding happens in slack now

talkpython.fm/episodes/show/…

It was a pleasure and great fun to chat to @mkennedy on @TalkPython - we did a deep dive into the technical aspects of how we built Foundry120 and apply agentic AI to accelerate translational science in IBD and the principles that can generalise beyond IBD. We discussed Django, the practicalities of handling big datasets, using Azure and my journey into programming. Check it out here:

talkpython.fm/episodes/show/…

Just shipped a big update to the Talk Python Training app! Rebuilt on the latest Flutter, iPad & Android tablet support, way better offline handling, smoother video playback, and a pile of fixes. If you've got courses, take them on the go.

Grab it: training.talkpython.fm/apps

Your weekly #Python update is live. 🎉

Six Feet Up CTO @calvinhp is joining @mkennedy as the new co-host of @pythonbytes every Tuesday at 10am ET. 🎙️🐍

🔴 Watch live now, and subscribe on YouTube to follow along each week: youtube.com/watch?v=WIykgb…

Spanish subtitles available for all courses:

¡Hola, estudiantes! Spanish subtitles are now live across every Talk Python course. All 283 hours, fully translated.

talkpython.fm/blog/posts/spa… cc @mkennedy

Our latest course is out!

Python Web Security: OWASP Top 10 with Agentic AI

Learn each of the 2025 OWASP in Flask, FastAPI, and Django. Then build an agent and find your bugs before anyone else does by @mkennedy

training.talkpython.fm/courses/agenti…

Latest episode is out: #548: Event Sourcing Design Pattern with Chris May and @mkennedy

talkpython.fm/episodes/show/…

Announcing German Subtitles on Talk Python Courses! cc @mkennedy

German subtitles and transcripts are now live on every Talk Python course. Switch the player's CC to Deutsch in one click, resize captions to your liking, and watch for Spanish coming next.

talkpython.fm/blog/posts/ann…

had a blast speaking with @mkennedy a few weeks back on deep agents!

talkpython.fm/episodes/show/…

Introducing the new Talk Python web player.

It starts out minimal, but once you trigger it, you can change the playback speed, it remembers your position, and , it shows the transcript live below the player so you don’t miss a word.

talkpython.fm/blog/posts/reb…

Fun episode with @IronicBadger and host @mkennedy talking Self hosting for Python devs and data scientists.

talkpython.fm/episodes/show/…

Does any one know whether Claude Mythos was shared with the CPython team to check for issues before its impending release? How about with web framework teams like FastAPI, Flask, Pydantic, etc? Web server projects like nginx?

Any recommendations on who to invite for a "self-hosted apps" topic on @TalkPython?

They don't need to be the creator of a self hosted app necessarily, but Python-leaning and experienced in self-hosting web apps is the key. (You can invite yourself).

Announcing Course Completion Certificates at Talk Python. Download or add them as a credential on your LinkedIn profile. Read more about it here:

talkpython.fm/blog/posts/ann…

Latest episode is out: #543: Deep Agents: LangChain's SDK for Agents That Plan and Delegate with @sydneyrunkle and @mkennedy. Give it a listen:

talkpython.fm/episodes/show/…

New essay: Cutting Python Web App Memory Over 31%

I reduced Python web app memory by 3.2 GB using async workers, import isolation, the Raw+DC database pattern, and disk caching. Detailed before and after numbers for each technique.

mkennedy.codes/posts/cutting-…

Your #Python team might be optimizing the wrong things. 🐍

Tooling, runtimes, and deployment practices are evolving fast. Teams are struggling to keep up. ⚡

What are the most important shifts? 🎙️ @TalkPython host @mkennedy, @calvinhp, @pwang discuss: sixfeetup.com/company/news/p…

Follow up post to my Raw+DC design pattern post last month, with numbers.

Raw+DC Database Pattern: A Retrospective
mkennedy.codes/posts/raw-dc-a…

Latest episode with @squidfunk and @mkennedy

#542: Zensical - a modern static site generator
talkpython.fm/episodes/show/…

w00t pytheory has docs now pytheory.kennethreitz.org