Everyone worries that doctors will trust AI too much. A study published yesterday in The Lancet Digital Health found that the bigger problem is the opposite.
A team led by the psychologist Susanne Gaube of University College London asked 50 radiologists and 75 other physicians and medical trainees to read head CT scans and decide whether there was bleeding in the brain. Each of them read one set of 50 scans alone, another with a plain AI verdict, and a third with an AI verdict that also marked where it saw the bleed. The twist: one in five AI answers was deliberately wrong.
Both mistakes happened. Some doctors followed the machine when it was wrong. But more damage came from doctors who ignored it when it was right, usually on the cases where they felt least sure. When the AI showed its evidence on the image, the odds of a correct diagnosis were 84% higher than reading alone. On the hardest bleeds, the non-radiologists with that marked-up AI even did better than the radiologists who had it too.
Explanations did not fully protect anyone from bad advice, so this is no argument for blind trust. It is an argument against a lazy idea of safety. At Certuma we are building autonomous AI medicine, and I don't believe the answer is a human second-guessing every correct call. A tired doctor overruling a right answer is not a safety net. It is a new source of error. What works is AI that shows its evidence and knows when it is unsure, with doctors focused on exactly those cases.
A human in the loop only helps if that human knows when to listen.
A team led by the psychologist Susanne Gaube of University College London asked 50 radiologists and 75 other physicians and medical trainees to read head CT scans and decide whether there was bleeding in the brain. Each of them read one set of 50 scans alone, another with a plain AI verdict, and a third with an AI verdict that also marked where it saw the bleed. The twist: one in five AI answers was deliberately wrong.
Both mistakes happened. Some doctors followed the machine when it was wrong. But more damage came from doctors who ignored it when it was right, usually on the cases where they felt least sure. When the AI showed its evidence on the image, the odds of a correct diagnosis were 84% higher than reading alone. On the hardest bleeds, the non-radiologists with that marked-up AI even did better than the radiologists who had it too.
Explanations did not fully protect anyone from bad advice, so this is no argument for blind trust. It is an argument against a lazy idea of safety. At Certuma we are building autonomous AI medicine, and I don't believe the answer is a human second-guessing every correct call. A tired doctor overruling a right answer is not a safety net. It is a new source of error. What works is AI that shows its evidence and knows when it is unsure, with doctors focused on exactly those cases.
A human in the loop only helps if that human knows when to listen.
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¿Cuando se va a dar cuenta España que tanto en Ceuta como en la península Ibérica está en guerra contra los mismos saqueadores?
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Martin Varsavsky retweeted
Llega la insurrección musulmana y africana a Barcelona con asaltos e incendios a negocios sin razón alguna.
Caos absoluto en el centro con decenas de negocios saqueados por la morralla y chusma magrebí.
Es una insurrección coordinada en toda Europa. Hace falta sacar el ejército.
Caos absoluto en el centro con decenas de negocios saqueados por la morralla y chusma magrebí.
Es una insurrección coordinada en toda Europa. Hace falta sacar el ejército.
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Martin Varsavsky retweeted
No son peligrosos grupos de ultraderecha sino radicales de extrema izquierda junto a magrebíes quienes ponen en peligro la seguridad en las calles de España.
Esto es Barcelona, ahora mismo.
Esto es Barcelona, ahora mismo.
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Madrid ha orientado su inmigración hacia países de habla hispana, de modo que la enorme mayoría de los niños, incluidos los de origen extranjero, hablan español en casa. En Cataluña el cambio ha sido más brusco: hace décadas, cuando no se hablaba catalán en el hogar se hablaba español, pero ahora una parte creciente de las familias procede de Marruecos, Pakistán, Bangladés y otros países de Asia y el norte de África y no habla ni catalán ni español en casa.
Esa diferencia se refleja en los resultados educativos: en PISA, Cataluña ha cosechado resultados especialmente malos, con una caída acusada que los analistas relacionan con el alto porcentaje de alumnos que llegan a la escuela sin dominar ninguna de las dos lenguas oficiales.
También se aprecia en la economía. En 2024 el PIB per cápita de Madrid era de unos 44.755 euros, frente a los 37.426 de Cataluña, una brecha de más de 7.000 euros que se ha ampliado desde el procés, mientras Madrid ha ganado peso en el PIB nacional. El proyecto nacionalista se enfrenta además a un límite demográfico claro.
Según el INE, casi el 47 % de los residentes de 25 a 39 años en Cataluña ha nacido en el extranjero, y el apoyo a la independencia es mucho más bajo entre quienes tienen padres nacidos fuera de Cataluña o son inmigrantes (alrededor del 27 % según los barómetros del CEO). Para una parte creciente de la población joven el independentismo no forma parte de su experiencia familiar ni de su identidad de origen, lo que reduce su base social más allá de los catalanes de varias generaciones.
Tener una proporción de inmigrantes no hispanos tan altas le costo a Cataluña mas paro, menos ingresos, peores resultados educativos, peores ingresos, mas criminalidad, en fin un desastre.
Esa diferencia se refleja en los resultados educativos: en PISA, Cataluña ha cosechado resultados especialmente malos, con una caída acusada que los analistas relacionan con el alto porcentaje de alumnos que llegan a la escuela sin dominar ninguna de las dos lenguas oficiales.
También se aprecia en la economía. En 2024 el PIB per cápita de Madrid era de unos 44.755 euros, frente a los 37.426 de Cataluña, una brecha de más de 7.000 euros que se ha ampliado desde el procés, mientras Madrid ha ganado peso en el PIB nacional. El proyecto nacionalista se enfrenta además a un límite demográfico claro.
Según el INE, casi el 47 % de los residentes de 25 a 39 años en Cataluña ha nacido en el extranjero, y el apoyo a la independencia es mucho más bajo entre quienes tienen padres nacidos fuera de Cataluña o son inmigrantes (alrededor del 27 % según los barómetros del CEO). Para una parte creciente de la población joven el independentismo no forma parte de su experiencia familiar ni de su identidad de origen, lo que reduce su base social más allá de los catalanes de varias generaciones.
Tener una proporción de inmigrantes no hispanos tan altas le costo a Cataluña mas paro, menos ingresos, peores resultados educativos, peores ingresos, mas criminalidad, en fin un desastre.
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Ja! buenisimo, aquí los espero en Estados Unidos!
Estamos mis hijos y yo en el aeropuerto y empiezan a quejarse de la camiseta que llevo: "Ceuta no se vende".
"Que ni siquiera eres española, qué vergüenza, la policía de inmigración te va a odiar…" Qué duros son los adolescentes.
Les digo: "La policía no. Los marroquíes a lo mejor sí"
Llegamos al control. El policía mira mi pasaporte y me pregunta:
"¿Varsavsky?"
Y me suelta:"Me encanta lo claro que hablan usted y su marido en redes y en la tele. Muchas gracias."
Me giro hacia mis hijos, les sonrío y pienso: "Qué era eso de la vergüenza? 1-0 para mí" 😅
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Martin Varsavsky retweeted
¡Felices 17 años de casados, mi amor @martinvars ! Y más de 20 años juntos…😳
Tres hijos maravillosos, mil aventuras, y alguna que otra discusión…Menos mal que tienes una mujer con tanta paciencia como yo 😅
Te quiero ❤️
Tres hijos maravillosos, mil aventuras, y alguna que otra discusión…Menos mal que tienes una mujer con tanta paciencia como yo 😅
Te quiero ❤️
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Cancer vaccines
It is now widely believed that cancer is not as rare as clinical statistics once suggested. Mutations that can start a tumor arise frequently throughout life, yet most of these early abnormal cells are successfully recognized and eliminated by the immune system before they ever become detectable. What we diagnose and treat as cancer is, in large part, the subset of cases in which that surveillance fails: the mutated cells manage to hide, suppress local immunity, or simply outpace the response, allowing a tumor to grow.
This view helps explain why people whose immune systems are severely weakened, such as those with advanced untreated HIV, develop certain cancers at far higher rates. It also supplies the logic for a new kind of vaccine. Cancer vaccines.
Unlike traditional vaccines that prevent infection in healthy people, cancer vaccines are given after a tumor has already formed, usually after surgery. They present the abnormal proteins created by the cancer’s mutations so that T cells can be retrained to recognize and clear the remaining cells the immune system had previously failed to control. In this sense the vaccines are an attempt to restore the protection that normally keeps most nascent cancers in check.
It is now widely believed that cancer is not as rare as clinical statistics once suggested. Mutations that can start a tumor arise frequently throughout life, yet most of these early abnormal cells are successfully recognized and eliminated by the immune system before they ever become detectable. What we diagnose and treat as cancer is, in large part, the subset of cases in which that surveillance fails: the mutated cells manage to hide, suppress local immunity, or simply outpace the response, allowing a tumor to grow.
This view helps explain why people whose immune systems are severely weakened, such as those with advanced untreated HIV, develop certain cancers at far higher rates. It also supplies the logic for a new kind of vaccine. Cancer vaccines.
Unlike traditional vaccines that prevent infection in healthy people, cancer vaccines are given after a tumor has already formed, usually after surgery. They present the abnormal proteins created by the cancer’s mutations so that T cells can be retrained to recognize and clear the remaining cells the immune system had previously failed to control. In this sense the vaccines are an attempt to restore the protection that normally keeps most nascent cancers in check.
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Case in point
The vaccine for melanoma, described by experts as a “game-changer” cuts the risk of patients dying or cancer returning by 42 per cent, trials have found.
Intismeran, produced by Moderna, is custom-built for patients who have had a melanoma removed, using a sample of the growth. th AI to create the vaccine ⤵️
telegraph.co.uk/news/2026/10/2…
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Me acabo de enterar sobre las ventajas de tomar choline que está disponible en Amazon o farmacias y es mucho más importante de lo que parece.
La colina es un nutriente esencial que el cuerpo produce en pequeñas cantidades, pero no suficientes. La mayoría de la gente no llega a las cantidades recomendadas solo con la dieta (huevos, hígado, carne, pescado y algunas verduras).
Sus principales beneficios:
•Es clave para el cerebro: ayuda a formar la acetilcolina, un neurotransmisor fundamental para la memoria, el estado de ánimo y el control muscular.
•Apoya el desarrollo cerebral del bebé durante el embarazo. Un estudio reciente de la Universidad de Colorado con altas dosis de fosfatidilcolina mostró que los hijos de las madres que la tomaron tuvieron en promedio unos 8 puntos más de CI a los 4 años y muchos menos problemas de retraimiento social.
•En adultos ayuda a mantener la función cognitiva y hay evidencia de que un consumo adecuado se asocia con menor riesgo de deterioro cognitivo y Alzheimer (especialmente si se obtiene de la dieta).
•Protege el hígado al ayudar a transportar las grasas y evitar que se acumulen.
¿Alguien ya lo está tomando? Estoy pensando agregarlo a mi dieta.
La colina es un nutriente esencial que el cuerpo produce en pequeñas cantidades, pero no suficientes. La mayoría de la gente no llega a las cantidades recomendadas solo con la dieta (huevos, hígado, carne, pescado y algunas verduras).
Sus principales beneficios:
•Es clave para el cerebro: ayuda a formar la acetilcolina, un neurotransmisor fundamental para la memoria, el estado de ánimo y el control muscular.
•Apoya el desarrollo cerebral del bebé durante el embarazo. Un estudio reciente de la Universidad de Colorado con altas dosis de fosfatidilcolina mostró que los hijos de las madres que la tomaron tuvieron en promedio unos 8 puntos más de CI a los 4 años y muchos menos problemas de retraimiento social.
•En adultos ayuda a mantener la función cognitiva y hay evidencia de que un consumo adecuado se asocia con menor riesgo de deterioro cognitivo y Alzheimer (especialmente si se obtiene de la dieta).
•Protege el hígado al ayudar a transportar las grasas y evitar que se acumulen.
¿Alguien ya lo está tomando? Estoy pensando agregarlo a mi dieta.
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Martin Varsavsky retweeted
Lo de ayer fue vergonzoso.
Ver a miembros del Gobierno y del @PSOE burlándose de la «técnica de la pizza», ignorando que detrás de la okupación hay miles de personas sufriendo, resulta indignante.
No hablamos de una pizza. Hablamos de víctimas que merecen respeto.
Ver a miembros del Gobierno y del @PSOE burlándose de la «técnica de la pizza», ignorando que detrás de la okupación hay miles de personas sufriendo, resulta indignante.
No hablamos de una pizza. Hablamos de víctimas que merecen respeto.
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Macron has had nine years to stop this. Le Pen will need a few weeks by sending a much tougher message to criminals disguised as protesters.
Last Saturday rioters burned the town hall of Limoges, a 19th century building in the middle of France, until the roof caved in. Police eople in one day. More than 3,000 shops were smashed or looted in Paris, Lyon, Marseille and dozens of other cities. More than 500 police officers were injured.
These are the criminals, the looters and the alliance of Islamists and leftists who want to destroy France. The looters move in gangs of 50 to 200, called up on social media, and empty a store in minutes.
Macron's interior minister, Laurent Nuñez, admitted the police "lost control" of France's biggest cities and offered to resign. Macron kept him which is another sign of failure. That is Macron's France: a country that can't protect its own town halls.
My wife @ninavars and I know these gangs firsthand. At the 2022 Champions League final, Liverpool against Real Madrid, my wife, our two little boys and I were mugged outside the Stade de France in Saint-Denis. There were thousands of them, Africans and French of African descent, and not one of them was white. It was a racist attack of black on white, those that when I used to be progressive didn’t know could actually occur. The police were completely overwhelmed. They mocked our boys for being white and threatened them, and with my wife and children under attack they stole 6,000 euros worth of tickets from us and run away with their booty. Macron's interior minister at the time, Gérald Darmanin, blamed the chaos on Liverpool fans with fake tickets. The French Senate later found the fans had been blamed to cover up the failures of the organizers. Darmanin is now Macron's justice minister. That night made me anti mass migration from countries incompatible with Western culture.
Macron's answer this time was curfews, speeches and soldiers sent to stand guard in front of buildings, a full week after Limoges burned. Four days after the riots only 149 people were still in custody. Everyone else is back on the street.
Le Pen would do the opposite.
Last Saturday rioters burned the town hall of Limoges, a 19th century building in the middle of France, until the roof caved in. Police eople in one day. More than 3,000 shops were smashed or looted in Paris, Lyon, Marseille and dozens of other cities. More than 500 police officers were injured.
These are the criminals, the looters and the alliance of Islamists and leftists who want to destroy France. The looters move in gangs of 50 to 200, called up on social media, and empty a store in minutes.
Macron's interior minister, Laurent Nuñez, admitted the police "lost control" of France's biggest cities and offered to resign. Macron kept him which is another sign of failure. That is Macron's France: a country that can't protect its own town halls.
My wife @ninavars and I know these gangs firsthand. At the 2022 Champions League final, Liverpool against Real Madrid, my wife, our two little boys and I were mugged outside the Stade de France in Saint-Denis. There were thousands of them, Africans and French of African descent, and not one of them was white. It was a racist attack of black on white, those that when I used to be progressive didn’t know could actually occur. The police were completely overwhelmed. They mocked our boys for being white and threatened them, and with my wife and children under attack they stole 6,000 euros worth of tickets from us and run away with their booty. Macron's interior minister at the time, Gérald Darmanin, blamed the chaos on Liverpool fans with fake tickets. The French Senate later found the fans had been blamed to cover up the failures of the organizers. Darmanin is now Macron's justice minister. That night made me anti mass migration from countries incompatible with Western culture.
Macron's answer this time was curfews, speeches and soldiers sent to stand guard in front of buildings, a full week after Limoges burned. Four days after the riots only 149 people were still in custody. Everyone else is back on the street.
Le Pen would do the opposite.
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Martin Varsavsky retweeted
Ya comenzaron con su agenda para mostrar cómo religión de paz al Islam. No falta nada para que empecemos a ver cómo lo quieren instalar en colegios, universidades y medios de comunicación.
Es importante entender que si permitimos esto, Argentina se rompe.
Es importante entender que si permitimos esto, Argentina se rompe.
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For the first time, a cancer medicine designed for one single patient has worked in a large phase three trial.
This week at ESMO, the big European oncology congress, Merck and Moderna presented INTerpath-001. They enrolled 1,137 people whose high-risk melanoma had already been removed by surgery. All of them got Keytruda, the standard immunotherapy, and two out of three also got intismeran, an mRNA shot built from their own tumor.
How do you make a medicine for one person? You sequence the tumor and a blood sample, software picks up to 34 mutations that only that cancer has, and those are written into an mRNA molecule that teaches the immune system what to hunt. A different drug for every patient, and they managed to manufacture it for more than 99% of the patients who were meant to receive it.
The result: after two years, 82.2% of patients on the combination were still free of cancer, versus 70% on Keytruda alone. The risk of recurrence or death fell 42%, and 58% once the six-month immunization was complete. Survival data are not mature yet, and this is only melanoma, but there are already three phase three trials in lung cancer.
The oncologist Georgina Long, principal investigator of the trial at Melanoma Institute Australia, put it well: "For decades, cancer treatment has largely been defined by where a tumor originates in the body."
That era is ending. Medicine is moving from treating the average patient to treating you.
This week at ESMO, the big European oncology congress, Merck and Moderna presented INTerpath-001. They enrolled 1,137 people whose high-risk melanoma had already been removed by surgery. All of them got Keytruda, the standard immunotherapy, and two out of three also got intismeran, an mRNA shot built from their own tumor.
How do you make a medicine for one person? You sequence the tumor and a blood sample, software picks up to 34 mutations that only that cancer has, and those are written into an mRNA molecule that teaches the immune system what to hunt. A different drug for every patient, and they managed to manufacture it for more than 99% of the patients who were meant to receive it.
The result: after two years, 82.2% of patients on the combination were still free of cancer, versus 70% on Keytruda alone. The risk of recurrence or death fell 42%, and 58% once the six-month immunization was complete. Survival data are not mature yet, and this is only melanoma, but there are already three phase three trials in lung cancer.
The oncologist Georgina Long, principal investigator of the trial at Melanoma Institute Australia, put it well: "For decades, cancer treatment has largely been defined by where a tumor originates in the body."
That era is ending. Medicine is moving from treating the average patient to treating you.
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La alianza de la izquierda con el islamismo está destruyendo Francia. La Francia Insumisa de Mélenchon llamó discriminación a la prohibición de la abaya en los colegios y ahora promete revertirla. Francia gasta 57% de su PIB en el gobierno, es más socialista que China que gasta el 30%, y aun así los socialistas unidos a los islamistas le queman el país pidiendo más por no hacer nada. Francia es hoy en día un desastre de país.
España va por el mismo camino. En enero el Gobierno de Sánchez pactó con Podemos regularizar a más de un millón de inmigrantes sin pasar por el Congreso. El 30 de julio 80 mil invasores entraron en Ceuta y la izquierda les llama personas migrantes y les quiere distribuir por España.
Suiza tiene un 27% de extranjeros y hace lo que España no se atreve a hacer: mandar de vuelta a casa a los que no trabajan.
El 29N se elige rumbo. El PP propone un visado de trabajo temporal ligado al contrato: si se acaba el trabajo, el inmigrante vuelve a su país. Y que los extranjeros cobren el ingreso mínimo vital solo si han cotizado o tienen residencia de larga duración. Vox va más lejos: devolución inmediata de quien entra ilegalmente y salida de quien vive de ayudas.
Quien trabaja, cotiza y cumple la ley, bienvenido, venga de donde venga. Quien entra ilegal, de vuelta a Marruecos o a donde sea. El Estado de bienestar, para quien lo paga y se lo merece.
Francia ya enseña adónde lleva el otro camino.
Vota PP, vota Vox.
España va por el mismo camino. En enero el Gobierno de Sánchez pactó con Podemos regularizar a más de un millón de inmigrantes sin pasar por el Congreso. El 30 de julio 80 mil invasores entraron en Ceuta y la izquierda les llama personas migrantes y les quiere distribuir por España.
Suiza tiene un 27% de extranjeros y hace lo que España no se atreve a hacer: mandar de vuelta a casa a los que no trabajan.
El 29N se elige rumbo. El PP propone un visado de trabajo temporal ligado al contrato: si se acaba el trabajo, el inmigrante vuelve a su país. Y que los extranjeros cobren el ingreso mínimo vital solo si han cotizado o tienen residencia de larga duración. Vox va más lejos: devolución inmediata de quien entra ilegalmente y salida de quien vive de ayudas.
Quien trabaja, cotiza y cumple la ley, bienvenido, venga de donde venga. Quien entra ilegal, de vuelta a Marruecos o a donde sea. El Estado de bienestar, para quien lo paga y se lo merece.
Francia ya enseña adónde lleva el otro camino.
Vota PP, vota Vox.
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