Pinned Tweet
Thread/

New @AHAScience Scientific Statement published online in @CircAHA regarding Interventional Therapies for Acute PE:

ahajournals.org/doi/10.1161/CI…

Presented simultaneously at @PERTConsortium PE symposium.

Summary in this thread.
5
55
141
Jay Giri retweeted
These distinguished Program Directors of #TCT2026 have put together a packed program of late-breaking trials and clinical science, symposia, abstracts, awards, and many features. It all begins this Saturday, October 31 in San Diego tctconference.com @crfheart @TCTConference
1
7
15
1,236
Jay Giri retweeted
Design of the Gujarat Tribal Genome Project nature.com/articles/s4158… @NatureGenet
1
16
65
6,822
Jay Giri retweeted
We are pleased to announce that @anna_bortnick has joined the Division of Cardiology as Professor of Medicine, Director of the Interventional Cardiology and Cardiac Cath Labs in the Stony Brook Heart and Vascular Institute @StonyBrookMed bit.ly/4kiddnu
2
2
28
1,277
Jay Giri retweeted
⏳TCT 2026 is just around the corner! 🫀

With dozens of our past BackTable Cardiology hosts and guests featured throughout the program, take a look at where they’ll be sharing their expertise so you don’t miss their sessions!

Download the BackTable app to stay prepped ahead of /t.co/tbyuwSdyy0

#TCT2026 #BackTableCardiology #InterventionalCardiology #Cardiology #CardioTwitter

@TCTMD @TCTConference @crfheart @jaygirimd @AGoldsweig @HadyLichaaMD @Samsayfo
0
3
7
352
Jay Giri retweeted
Robert A Lookstein, MD, FSIR, FSVM Top 10 Advances in Pulmonary Embolism youtu.be/0JiNxds3i6g?si… via @YouTube
0
1
13
1,549
Jay Giri retweeted
Honored to receive the @TCTConference 2026 Geoffrey O. Hartzler Master Operator Award. This belongs to everyone who has championed imaging in structural heart disease. Join me Sun 11/1, 9:40 AM PT, Opening Session, Hall H. bit.ly/TCT2026_Award @ASE360 @ACCinTouch @escardio
12
12
121
4,694
Jay Giri retweeted
Clinical departments reportedly being cut by Mass General Brigham @MassGenBrigham
MGB's last round of layoffs focused on administrative roles. Now the health system is looking to restructure clinical departments. bizjournals.com/boston/news/20…
15
14
161
78,639
Jay Giri retweeted
Is a larger catheter always the answer for removing pulmonary emboli?

Dr. Jay Giri (@jaygirimd) and Dr. Julie Bulman (@juliecbulman) join Dr. Chris Beck (@beckcj) to weigh the benefits and pitfalls of large-bore versus medium-bore catheters, and share tricks for navigating tough more problems.

Access the full episode in the BackTable app:
backtable.com/shows/vi/podca…

This podcast is supported by Endovascular Engineering.

#VI677 #CV53 #PE #Thrombectomy #InterventionalRadiology #Cardiology @PennMedicine @PERTConsortium @BIDMCVIR
0
3
19
947
Jay Giri retweeted
Excited to launch the new Center for Surgical and Medical Intelligence @SmithBIDMC

Led by national leaders in clinical AI, @AdamRodmanMD & @bratogram, the Center will bring together expertise across BILH to advance AI across medicine and procedural care
bilh.org/about/news-and…
4
10
65
4,909
Jay Giri retweeted
Corelab annotations are a lot of work. Frame after frame, contour after contour, and the software we had made it hard.

So I built our own with @claudeai.

It’s called Coronaut. It was made entirely with Claude Code, to solve a problem we lived with every day. It takes an IVUS he lumen, EEM and stent struts automatically. I think it does a much better job than the software we had available. It also does 3D reconstructions and calculates FFR from the lumen.

Was it fast or easy? No. It’s been more than a year in the making. But it allowed us to overcome a barrier that would otherwise have blocked us forever. I know how to code, but how long would it take me to do this by myself? Years?

When I say AI will revolutionize medicine, this is what I mean. This is where doctors and chips meet, and I think it’s beautiful.

Is it perfect? No. It is not finished or validated yet, and it is for research purposes only at this time. But we are working on it constantly, and it’s coming along.

#CardiologyX #IVUS #AI
9
33
156
17,727
Jay Giri retweeted
Intermediate-high risk used to be a murky call.

Dr. Jay Giri (@jaygirimd) and Dr. Julie Bulman (@juliecbulman) join Dr. Chris Beck (@beckcj) to explain the new guideline subgroups specifically how to spot a C3 versus a D2 patient, who needs escalation, and how real PERT teams ies to guide next steps.

Access the full episode in the BackTable app:
backtable.com/shows/vi/podca…

This podcast is supported by Endovascular Engineering.

#VI677 #CV53 #PE #PERT #Anticoagulation #Cardiology
@PennMedicine @PERTConsortium @BIDMCVIR
0
1
10
1,144
Jay Giri retweeted
Quick summary of the data (and our experience) with sedation in PE. The sicker the patient, the lighter the sedation.
4
2
29
1,710
Jay Giri retweeted
AI is causing academics to have midlife crises

“Should we publish papers?”

I do think there’s a path forward once AI use in research becomes common (soon). Values will shift away from authoring many publications and toward taste/substance of insight, curation, and communication/education. Reviewing and editorial work will be better recognized.
We had an online seminar recently. The speaker mentioned an open problem at the end of the talk, which would be a natural continuation of the published work. It seemed like a good problem. It asks whether or not a certain construction can exist. Well defined, natural, nice.

I asked Astra. It solved the problem after 2-3 prompts. The first solution (a concrete example) seems too simple, so I asked Astra to find something more complicated. Now there is a second example.

I asked Astra to explain to me why the solution works, this happened on the way back home from work. Travel on the tram and the metro used efficiently.

At home I also asked Astra to compile a research article. The end result is a good starting point for a paper. Of course it looks like AI slop, but it is way less slop then what earlier models would produce. It would take only a few days of concentrated work to make an actual journal quality paper out of it.

All of this feels... illegal, pointless, and exciting at the same time. So many conflicting emotions.

What do we gain from all of this? Should we publish papers? Or just shout into the world that we know an answer? I am really not sure.

Naturally, I informed the speaker, he was interested. I sent him the document. I am waiting for the answer.

Minimal efforts, some understanding, and now a new result that would seem non-trivial for most of my colleagues. A new paper that had been welcome and appreciated at any time pre-AI.

Where do we really go from here...
23
12
120
29,610
Jay Giri retweeted
We are releasing Ultramarine 1 Flash, a frontier-class model built for knowledge work. It is open-source and achieves similar performance to Fable 5, while being 60x cheaper.

It was post-trained by a team of 5 for ~$300k all-in. Available on API now, with weights releasing in 2 weeks.
607
696
8,109
1,740,622
I’m no mathematician but the below appears more scientifically rigorous and transparent (with hopefully more room for accompanying actionable knowledge development) than the well publicized recent Open AI math proof dump.

Perhaps this is what mathematicians are upset about?
🧬 Training and evaluating AI scientists on drug target discovery is hard.

We introduce DrugTargetWorld: Synthetic Biomedical Worlds for Training and Benchmarking AI Scientists

The environment turns end-to-end drug target discovery into a problem where AI scientists can be l truth.

🎯 We’ve been able to hill climb on problems like Chess, Go, StarCraft, and even now computer science and mathematics because they have a verifiable reward.

We want to bring that to drug discovery.

Built with @BGomes_1905 @euanashley and an incredible team at Stanford and beyond.
1
0
6
968
Jay Giri retweeted
🧬 Training and evaluating AI scientists on drug target discovery is hard.

We introduce DrugTargetWorld: Synthetic Biomedical Worlds for Training and Benchmarking AI Scientists

The environment turns end-to-end drug target discovery into a problem where AI scientists can be l truth.

🎯 We’ve been able to hill climb on problems like Chess, Go, StarCraft, and even now computer science and mathematics because they have a verifiable reward.

We want to bring that to drug discovery.

Built with @BGomes_1905 @euanashley and an incredible team at Stanford and beyond.
13
21
77
13,011
Jay Giri retweeted
Thrilled to see our paper — the largest study ever of pediatric Castleman disease — published and able to be used by clinicians to treat their pediatric patients! doi.org/10.1002/1545-5… please help to share this post so doctors are aware of this study and patients can benefit!
3
21
67
5,335
Jay Giri retweeted
Huge congrats to @AdamRodmanMD, @PeterBrodeurMD & the @Google team on the first prospective study of a patient-facing AI system in a real clinic in @TheLancet

AI can improve care, but rigorous evaluation has to be built in. More to come soon from Adam, Peter @SmithBIDMC
Today @TheLancet published our AMIE study with @BIDMC_Medicine, the first prospective study of patient-facing conversational diagnostics in a real clinic.

AMIE is a research system people can chat with before doctors appointments. Testing AMIE outside the lab with real urgent w technology can help gather medical histories safely. Clinicians reported that the summaries helped them prepare for visits in 75% of cases and influenced their approach to care in more than half. AMIE’s differential diagnoses also matched the doctors’ final diagnoses 90% of the time giving clinicians more time to focus on patient care.

It’s Google’s first-ever paper in The Lancet’s main journal!
1
6
41
1,821
Jay Giri retweeted
I practiced academic oncology for 10 years and now I am at a large community practice. In retrospect I realize how foolish I must have sounded when giving talks to the community. It's a different world in the real world.
36
37
633
94,281
Jay Giri retweeted
👀Here’s an example of why you NEVER want to use a hydrophilic wire through a needle.

⚠️High risk of sheering off the hydrophilic coating in the vessel/tissue

🔗fixed core/nitinol based wire should mainly be used for access. In micropuncture I prefer the 0.018 Nitex rdioX #peripheral
5
28
146
31,158