Really excited to share our new review paper on GxE! Team work with three graduate students: Carly Boye, Shreya Nirmalan, Ali Ranjbaran link.springer.com/10.1038/s41588…

Excited to share our science at #ASHG26: 6034W, 6035T, GxE Symposium Friday 8:15 Room 511

I wanted to like QED's new 1% preprint ranking. But the more I looked at the data, the more uncomfortable it made me. Here is my full peer review:

open.substack.com/pub/blekhman/p…

The abstract deadline for Midwest Popgen 2026 has been extended to June 12! jkreinz.github.io/mwpg2026/

📣 New PRBB-CRG conference

📋 Genetic and social factors in gene regulation and health
🗣️ @fluca2406 - @UChicago

📆 May 18 - ⏰ 12:00
hosted by: Silvia Pérez-Lluch - @CRGenomica

📍 #PRBB Maria Skłodowska-Curie room

UChicago DNA Days teach hundreds of Chicago schoolchildren what it’s like to be a scientist | Biological Sciences Division | The University of Chicago biologicalsciences.uchicago.edu/news/uchicago-…

AI has huge promise for genomics -- but it has consistently failed at microbiome-based prediction.

My new post on why simple models keep winning, where deep learning actually earns its place, and where the field is headed.

blekhman.substack.com/p/ai-keeps-fai…

Our new paper, where we use metabolic modeling to show Fusobacterium grows faster in colorectal tumor microenvironments, and use computational + experimental approach to find specific metabolic pathways driving host-microbiome interactions in cancer
biorxiv.org/content/10.648…

🧬 🦠 🏙️ Urban vs rural lifestyles create dramatically different gut microbiomes. But how do these different gut microbiomes affect the host?
Excited to share our new paper: biorxiv.org/content/10.110…

This project was brilliantly led by Sabrina Arif (@microsabz), and is a close collaboration with @fluca2406's lab, and the Global Microbiome Conservancy (@mgroussi and @mathildpoyet)

New preprint: Psychological stress and social support are associated with opposing single-cell pro-inflammatory gene regulatory mechanisms in adults

"Single-cell genomics of peripheral immune cells reveals that social support is associated w/ anti-inflammatory gene regulatory mechanisms in older adults" —Francesca Luca, PhD

To learn more about Dr. Luca's work, check out these posters and session below ⤵️#ASHG25

The Luca Lab is ready for Halloween!

Ready, set, go! First experiment in the new lab is underway. Thanks to Shreya Nirmalan and Gabrielle Garlicki the Luca Lab is up and running at UChicago!

It’s time for the official announcement: the Luca Lab is moving to UChicago ⁦⁦⁦@HGEN_UChicago⁩ - get in touch if you are interested in studying GxE in the Windy City!

Looking forward to participating and presenting our work w/ @rogerpique on "Gene expression changes in immune cells during the peripubertal period" nia.nih.gov/research/works…

I am super excited to be presenting today at #ASHG23 PB3452

Great to be here #ASHG2023! See you this pm at poster #PB1192 by MD/PhD student Shreya Nirmalan “Microbiome and host genetic effects on gene regulation in Inflammatory Bowel Disease” w/ @rogerpique @blekhman

NHGRI is having a workshop - Advances in the Genetic Architecture of Complex Human Traits - organized by @NancyGenetics, @lorin_crawford, @molly_przew, and Peter Visscher.

Thurs 16th - Fri 17th November
Register for the webinar here: nih.zoomgov.com/webinar/regist…