Emma Alexander retweeted
⁉️When to extubate after a child receives a liver transplantation?
⚡️Our meta-analysis of 12 studies found
immediate extubation associated with lower reintubation, mortality, and shorter length of stay.
@PALISInet Liver Failure Special Interest Group #PALF @PICJournalWatch coDaverioMD @MattGoldPedsCCM Giacomo Berti, Goda Laucaityte, @emmaaaaa8
#pediatrics #childhealth #livertranslantation
#PedsICU @pccm_doc @DfarmerDouglas @VSLanziotti #pediatricacuteliverfailure
Immediate vs delayed extubation after pediatric liver transplantation: a systematic review and meta-analysis | European Journal of Pediatrics | Springer Nature Link
⚡️Our meta-analysis of 12 studies found
immediate extubation associated with lower reintubation, mortality, and shorter length of stay.
@PALISInet Liver Failure Special Interest Group #PALF @PICJournalWatch coDaverioMD @MattGoldPedsCCM Giacomo Berti, Goda Laucaityte, @emmaaaaa8
#pediatrics #childhealth #livertranslantation
#PedsICU @pccm_doc @DfarmerDouglas @VSLanziotti #pediatricacuteliverfailure
Immediate vs delayed extubation after pediatric liver transplantation: a systematic review and meta-analysis | European Journal of Pediatrics | Springer Nature Link
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Emma Alexander retweeted
We are organising a workshop on continuous renal replacement therapy in critical ill children at @WFPICCS in Melbourne, 26th Sept, 2026 Hands-on experience with eminent faculty from the field
- limited seats
@burns_md @ESPNIC_Society @BasuND22 @PICSociety @emmaaaaa8 #PedsICU
- limited seats
@burns_md @ESPNIC_Society @BasuND22 @PICSociety @emmaaaaa8 #PedsICU
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Emma Alexander retweeted
How can we get to the bottom of this seeming paradox? We need to go deep into the supplement!
The key is understanding how clinicians deal with discrepant information.
The reduction in mortality was driven by the subset with a high NEWS score and a low procalcitonin. These are ut procalcitonin clinicians could erroneously mistakenly conclude “just have sepsis.” With the extra PCT data point, they were encouraged to reevaluate. This reduced mortality in the patients who ultimately did not have infection.
Conclusion: An additional test can help avoid premature closure and get you to reassess! If the data doesn’t fit reconsider!
(Sidebar: it’s pretty embarrassing that @TheLancet misspelled “Medium”)
The key is understanding how clinicians deal with discrepant information.
The reduction in mortality was driven by the subset with a high NEWS score and a low procalcitonin. These are ut procalcitonin clinicians could erroneously mistakenly conclude “just have sepsis.” With the extra PCT data point, they were encouraged to reevaluate. This reduced mortality in the patients who ultimately did not have infection.
Conclusion: An additional test can help avoid premature closure and get you to reassess! If the data doesn’t fit reconsider!
(Sidebar: it’s pretty embarrassing that @TheLancet misspelled “Medium”)
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Emma Alexander retweeted
The results of the PRONTO RCT of procalcitonin in people with suspected sepsis are absolutely fascinating.
Mortality was significantly lower in the procalcitonin-guided care group: 13.6% (372/2738) vs 16.6% (450/2715) (p=0.0009) but there was no difference in antibiotic or days of therapy!
So apparently procalcitonin saves lives even if it doesn’t change antibiotic prescribing? 🤔
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Mortality was significantly lower in the procalcitonin-guided care group: 13.6% (372/2738) vs 16.6% (450/2715) (p=0.0009) but there was no difference in antibiotic or days of therapy!
So apparently procalcitonin saves lives even if it doesn’t change antibiotic prescribing? 🤔
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Emma Alexander retweeted
Dear students in the UK, if you haven't had your teenage meningitis vaccine or aren't sure if you have had it, PLEASE arrange with your GP to get vaccinated nhs.uk/vaccinations/m… It helps prevent tragic deaths like those that have occured recently in Kent.
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Emma Alexander retweeted
Thrilled to share our paper is now published in the JICS
"Paediatric and adult neurological point-of-care ultrasound: Review of the evidence, and the UK accreditation pathway" Manprit Waraich, Bogdana Zoica, Emma Alexander 2026 journals.sagepub.com/doi/10.1177/17… 🧠
"Paediatric and adult neurological point-of-care ultrasound: Review of the evidence, and the UK accreditation pathway" Manprit Waraich, Bogdana Zoica, Emma Alexander 2026 journals.sagepub.com/doi/10.1177/17… 🧠
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This is a complete outrage @wesstreeting @karinsmyth @SKinnock @DHSCgovuk @zubirahmed @SharonHodgson - please help this doctor
Dr Elaine is the UK’s first deaf/blind doctor. She is under multiple specialists in London. She is on 24 hour LTOT.
Her request to be pre-allocated to London was declined and was allocated Dorset.
This is a catastrophic failure by the @UKFPO, who simply isn’t hated enough.
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Paediatric and adult neurological point-of-care ultrasound: Review of the evidence, and the UK accreditation pathway @bogster77 @ManniWaraich journals.sagepub.com/doi/10.1177/17…
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Emma Alexander retweeted
Paediatric diabetic ketoacidosis-associated acute liver failure in the post Covid era - series from Kings. Hepatic complications of DKA can be devastating.
doi.org/10.1002/jpn3.7…
@emmaaaaa8 @ESPNIC_Society #PedsICU @SCCM
doi.org/10.1002/jpn3.7…
@emmaaaaa8 @ESPNIC_Society #PedsICU @SCCM
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Terlipressin in paediatric hepatorenal syndrome-acute kidney injury (HRS-AKI) @aakashdeeparora
link.springer.com/article/10.100…
link.springer.com/article/10.100…
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Very interesting paper examining MgSO4 treatment implementation for preterm babies, and the cost-effectiveness of improving implementation. We need a similar focus in #PedsICU!
frontiersin.org/journals/healt…
frontiersin.org/journals/healt…
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Emma Alexander retweeted
Thank you very much for the opportunity. I look forward to working with you all. Please get in touch with me with any new ideas or interesting manuscripts.
Exciting news from EJP! 🎉
We’re welcoming a new expert in Paediatric Critical Care and Emergency Medicine to our Editorial Board to ensure top-quality service and editorial excellence.
Join us in welcoming Prof. Akash Deep! @aakashdeeparora @springer1842 @SpringerNature
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PICU colleagues in Czechia, Denmark, Finland, Germany, Greece, Kosovo, Lithuania, Romania, Spain, Ukraine - we are looking for an estimate of total # of PICU beds in your countries (as part of our ESPNIC project). Do you have an estimate? Thank you! @ESPNIC_Society
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TCD has amazing potential! Really excited to use it more in practice @bogster77
Very chuffed to share this work on Neuromonitoring in children with Acute Liver failure using transcranial Doppler and reversed jugular Venous saturations. If used consistently, can guide management and prognosis @ESPNIC_Society #PedsICU @SCCM @emmaaaaa8
gbr01.safelinks.protection.outlook.com/?url=https%3A%…
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Emma Alexander retweeted
Very chuffed to share this work on Neuromonitoring in children with Acute Liver failure using transcranial Doppler and reversed jugular Venous saturations. If used consistently, can guide management and prognosis @ESPNIC_Society #PedsICU @SCCM @emmaaaaa8
gbr01.safelinks.protection.outlook.com/?url=https%3A%…
gbr01.safelinks.protection.outlook.com/?url=https%3A%…
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Dual-phase machine learning framework for paediatric ventilator liberation: forecasting extubation readiness and nowcasting extubation outcomes bmjdigitalhealth.bmj.com/content/1/1/e0…
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Emma Alexander retweeted
It's hard to believe that a few weeks ago, I was in Critical Care on a ventilator with my heart, kidneys & liver failing. Now, I've just managed a litter pick. I had to stop after one bag as I'm not strong enough yet, but at least I've done something to help keep the area tidier.
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Really recommend this amazing course! 🤩
And spoke about neuroPOCUS to wider audiences. Our second cohort of beginners will start their learning next week. We have a few remaining spaces if you would like to join us uclhcharitycourses.com/courses/fusic-…
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Massive congratulations to the amazing @pic_pram! 🤩
Congratulations to @ImperialSandC's Prof Padmanabhan Ramnarayan on his prestigious @NIHRresearch Professorship 🎉
He'll lead research to personalise breathing support for critically ill children – transforming care across @ImperialNHS + beyond.
Read ➡️ imperial.ac.uk/news/270633/pr…
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