This @mjmaccoss preprint about QC is too real. Like when your turbo pump explodes and sends shrapnel into every crevice of your mass spec causing problems for half a year. This QC platform help you know when your instrument is actually all clean again :) biorxiv.org/content/10.110…
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FYI Bay area mass spec aficionados - this symposium on mass spec in drug discovery looks great! Oct 29th @ at Stanford
Join us for the inaugural SCI Advances in #MassSpectrometry Enabled Drug Discovery symposium on October 29. Hear leading experts explore current challenges, opportunities, & recent achievements across diverse applications in #DrugDevelopment. stan.md/3X0WVUC #proteomics
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Danielle Swaney retweeted
Interested in #proteomics/related data analysis but don't know where to start❓Our 2-day hands-on workshop🙌 @UCSF is for you!
July 11-12 at Mission Bay campus, open to Bay Area academic or industry scientists.
Info+registration (seats are limited!) wiitalab.ucsf.edu/events/biologi…
July 11-12 at Mission Bay campus, open to Bay Area academic or industry scientists.
Info+registration (seats are limited!) wiitalab.ucsf.edu/events/biologi…
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Danielle Swaney retweeted
Did you know that phage can inject DNA, many proteins, recruit host membrane/membrane proteins and assemble a lipid vesicle to protect the genome?@MozumdarDeepto led this effort with contributions from a large multi-disciplinary team. @cellhostmicrobe
sciencedirect.com/science/articl…
sciencedirect.com/science/articl…
The phiKZ jumbo phages build a protein based nucleus to protect their DNA(!), but what do they do before the nucleus is built? Led by outstanding post-doc @MozumdarDeepto, here we identify host and phage proteins in an immediate early phage lipid vesicle.
biorxiv.org/content/10.110…
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Bay area proteomics friends - Having some ASMS FOMO? Or just want to pregame for ASMS? Come attend our @QBI_UCSF and @rezo_tx Mass Spectrometry Symposium at UCSF on Thursday May 30, hosted by myself and Chris Adams. We have a diverse and spectacular lineup qbi.ucsf.edu/qbi-rezo-mass-…
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Also, a big thanks to our generous sponsors! Come hear from them about their latest and greatest technology and how it could help to accelerate your research. @thermofisher @bruker @NautilusBio @seer_bio
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In eRA Commons a green "Council review completed" status means a grant still has a chance for funding? I have an NIGMS grant with a fundable (but not amazing) score and it has been in this status since October. PO doesn't respond to email or call to discuss, so I am being patient
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Danielle Swaney retweeted
On #InternationalWomensDay, I want to throw back to this article I wrote for @eLifeCommunity about my abortion during my PhD. #WomenInSTEM don’t need pats on the back- we need institutional policies that protect our rights, our healthcare, & allow us to make our own choices. 1/2
"I have seen very little outrage – and even fewer tangible actions – from those who can influence policy, especially at research institutions."
A PhD student urges those in power to take a stand for reproductive rights. elifesciences.org/articles/82643…
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Danielle Swaney retweeted
Blocking access to Algebra in public middle schools hurts everyone. You can’t take Calculus by end of high school without it.
Banning access to math is the ultimate virtue signal with bad outcomes, and they’re going to force it California-wide
Banning access to math is the ultimate virtue signal with bad outcomes, and they’re going to force it California-wide
Becoming a data scientist: you'll need calculus early in college or hs, so you need Alg. II.
"[Students] should not be fed the false promise that by not learning certain core content in high school, that you will still have all options open in college.” kcrw.com/news/shows/pre…
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Andrea is awesome to work with! 10/10 would do it again. Creative, smart, and knows how to focus and get projects done. You are in for a fun ride if you work with him.
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Random shower thought: I would love to see a few famous scientists interviewed on the Hot Ones show.
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At my US HUPO lightning talk I made a silly slide about how using SEC-MS for studying host-pathogen interactions would stop classic Reviewer #2 critiques. It worked!! @anfossati got the best 1st round reviews ever. R2 says: "Thus, the paper can be accepted in its native form." 🥂
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Danielle Swaney retweeted
@TheCoxLab and @Coon_Labs scientists succeeded in developing a new method to generate a more detailed #proteome than ever before, providing insights into how #GeneticVariants and #SpliceVariants in humans impact the proteome.
Published in @NatureBiotech
nature.com/articles/s4158…
Published in @NatureBiotech
nature.com/articles/s4158…
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Thanks to all who responded to my Vanquish Neo call for help. Here is an update. TLDR: we think desalting tip C18 particles were leaking into final sample, building up on the needle seat, and retaining hydrophobic peptides. Full troubleshooting details: tinyurl.com/3v62rhnb
#VanquishNeo users - What do I have to do to make this LC like me? We got 3 installed recently and we are seeing this problem where we progressively lose signal during the gradient. Example image from earlier this month (top) vs. today (bottom). Happening on 2 of 3 LCs.
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Danielle Swaney retweeted
New preprint alert!
Here we show how SEC-MS is a powerful tool for host pathogen interactions profiling. We applied it to Jumbophages, which are large bacterial viruses (>300 genes) holding great potential as antibiotics.
What did we find? 1\n
biorxiv.org/content/10.110…
Here we show how SEC-MS is a powerful tool for host pathogen interactions profiling. We applied it to Jumbophages, which are large bacterial viruses (>300 genes) holding great potential as antibiotics.
What did we find? 1\n
biorxiv.org/content/10.110…
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#VanquishNeo users - What do I have to do to make this LC like me? We got 3 installed recently and we are seeing this problem where we progressively lose signal during the gradient. Example image from earlier this month (top) vs. today (bottom). Happening on 2 of 3 LCs.
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I firmly believe that greater equity in childhood education is a critical component to bringing greater diversity and equity to science. As you consider charitable donations this year, consider the PTA of a local public school supporting populations under-represented in science.
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Likely their PTA budgets are small and largely based on donations. As a member of such a PTA, I can confidently say your money will be immensely appreciated and well used. It will support things like math and literacy support teachers, field trips to local science museums, etc.
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PTA supported programs like these enrich student learning and have the potential to significantly change the trajectory of a child’s academic career, enabling greater access to college, and ultimately opening doors to careers that might otherwise have been closed.
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Hey @SFPD- not fucking good enough. Today an unhoused person snuck into my kid’s school playground and refused to leave. School went into lockdown. It took 78 min and 2 calls to 911 before police arrived. You were so damn slow the person had thankfully already left on their own.
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