1/4 Over the last few years, we’ve grown from working primarily with a single foundation to partnering with more philanthropists who share our commitment to high-impact giving.

To better reflect this, Open Philanthropy is becoming Coefficient Giving.

Short expressions of interest are due Dec 21 at 11:59 PM PST.

Full details: coefficientgiving.org/funds/science-…

We’re excited to announce that Joe Huston is joining us as Managing Director of Philanthropic Advisory! He’ll lead our Partnerships team, helping to manage our multi-donor funds and advise the next generation of major philanthropists.

More on Joe: coefficientgiving.org/research/intro…

Today we're launching the Health Aid Transition Fund: $165 million over the next few years to help low- and middle-income countries adapt their health systems amid rapidly declining aid: coefficientgiving.org/funds/health-a…

Aid is dropping faster than at any point on record. Over the next les, dozens of governments have to decide which donor-funded functions to absorb, which to cut, and how to deliver care with less. Those decisions will shape health systems for years.

Philanthropy alone can't close a gap this size, but it can play a critical role in supporting these countries during a period of transition. The Health Aid Transition Fund aims to support the technical work that makes scarcer resources go further: cost analyses, financing strategy, and getting budgeted money out the door to clinics and suppliers. The Fund will also bridge critical programs through the handover where that unlocks aid that would otherwise go unspent.

@glassmanamanda will lead the Fund, with Noemi Schramm Ndao as Senior Program Officer.

We talked with Amanda about what technical assistance can and can't do here, and why systems that countries own themselves may prove more resilient than what they replace: coefficientgiving.org/research/annou…

A chief of staff's primary output isn't their own work — it's their principal's.

Coefficient Giving currently has 10. In a new essay, three things we've learned about what makes someone effective in the role: protect your principal's time, make information gathering cheap, and architect how the work gets done.

Read here: coefficientgiving.substack.com/p/the-lowkey-h…

Today we're launching Project Tailwind, a major call for founders to launch ambitious AI safety initiatives: coefficientgiving.org/tailwind/?utm_…

We're looking for exceptional people to build the research, technologies, and institutions that will help humanity navigate the risks of transformative AI. 🧵

Funding is available at three levels:

1️⃣ Pre-seed: $200k to $2m to develop an idea and build a team
2️⃣ Seed: $2m to $20m to launch and scale
3️⃣ Scale: $20m to $200m+ for proven teams to scale, or world-class teams to start

If you have a strong track record and want to build something important, tell us who you are and what you'd build: coefficientgiving.org/tailwind/get-i…

Promising candidates will be invited to submit a longer proposal; especially strong candidates will be invited to a pitch meeting straightaway. We aim to decide quickly and disburse funds soon after.

Today we're opening Launchpad Funds, a request for expressions of interest to seed or scale funds tackling important, underfunded problems in global health and wellbeing.

Each fund should be built around a specific outcome and led by a "general manager" personally accountable for delivering it. 🧵

The application form is intentionally short; we expect it to take 1–2 hours.

Applications are due October 2, and we'll make decisions on a rolling basis: fillout.coefficientgiving.org/launchpad?camp…

This is one part of a broader acceleration of our global health and wellbeing giving in 2026-27.

More from our Executive Director of Global Health & Wellbeing, @otis_reid: coefficientgiving.substack.com/p/were-scaling…

Coefficient Giving is now on Substack!

Think of it as the front page of CG thought, curating the best writing from across our funds and staff into a single feed 🧵

3️⃣ A grantee spotlight on the Centre for Pesticide Suicide Prevention’s life-saving work: coefficientgiving.substack.com/p/banning-toxi…

The Substack is also the new home of our monthly newsletter. If you're already a subscriber, you don't have to do anything — we’ve automatically ported you over.

But if you’re new, consider subscribing for that + more: coefficientgiving.substack.com