CellType retweeted
How much does a rat liver response tell us about human cells?

Across 26 held-out compounds, CT-Tox achieved 0.74 rank agreement with measured human Hallmark pathway responses, versus 0.35 for copying rat responses to human genes.

celltype.com/blog/post/ct-t…
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CellType retweeted
Which patients will respond to immunotherapy?

Across 5 cohorts, 43% responded. In CT-Translate’s top-ranked third: 61%.

451 patients. Every prediction made by a model that never saw that patient.

Retrospective results:
celltype.com/blog/post/ct-t…
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Predicting patient outcomes from lab data is a long-sought goal in drug development.

Introducing CT-Translate, a preclinical-to-clinical foundation model built to do it.

In its top-ranked third of immunotherapy patients, 61% responded vs 43% overall.

celltype.com/blog/post/ct-t…
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Replying to @celltypeinc
One model, 69 clinical questions. In: a tumor profile, clinical details and a plain-English question. Out: a probability per patient, so patients can be ranked.

Built on CT1, our foundation model. Trained on drug screens and more than 13,000 patients across 20 studies.
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Replying to @celltypeinc
It runs on-prem, frozen and versioned on a single GPU, no external calls. Your fine-tuned weights stay on your premises and run on the licensed CellType foundation model.

Built with a top-10 pharma translational team. Test it on patients you hold out:
celltype.com/blog/post/ct-t…
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Replying to @celltypeinc
One model, 69 clinical questions. In: a tumor profile, clinical details and a plain-English question. Out: a probability per patient, so patients can be ranked.

Built on CT1, our foundation model. Trained on drug screens and more than 13,000 patients across 20 studies.
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Replying to @celltypeinc
It runs on-prem, frozen and versioned on a single GPU, no external calls. Your fine-tuned weights stay on your premises and run on the licensed CellType foundation model.

Built with a top-10 pharma translational team. Test it on patients you hold out:
celltype.com/blog/post/ct-t…
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