We're really excited that CD-CODE is now cross-referenced by @uniprot and has already been included in the latest release: uniprot.org/release-note...

Spreading knowledge about #biomolecular #condensates 🥳

🦋more news from us: bsky.app/profile/cdcode…

The latest release was supported by the #condesathon joined by MPI-CBG condensate community🤩 Big #thankyou to all the participants for your support and enthusiasm!💜

more news from us: bsky.app/profile/cdcode…

☀️summer is here - and so is CD-CODE v1.10 release!

💡CD-CODE has now 719 manually curated #condensates
💡Check out new #condensates and updated #protein - condensate connections at cd-code.org

#Bioinformatics #DatabaseUpdate #cdcode

bsky.app/profile/cdcode…

The latest April release of @uniprot cross-links biomolecular condensate entries to CD-CODE.
uniprot.org/release-notes/…

For example, one can see that Protein Q9VD51 is a member of the Nucleolus uniprot.org/uniprotkb/Q9VD…

@cdcode_org @agnestothp

🍃CD-CODE update v1.09 is here!🍃
👀Check out the new #biomolecular #condensates at cd-code.org
👀We're continuing to update #Protein - #condensate connections and resolve issues!

Join us on🦋 to follow more regular updates: cdcode.bsky.social

Our PICNIC tool predicts condensate-proteins regardless of their structural disorder across organisms
@NatureComms. Congratulations to @AHadarovich for developing the algorithm and to Hari @HymanLab for the experiments! @mpicbg @csbdresden @PoLDresden nature.com/articles/s4146…

✨Winter CD-CODE update to v1.08!✨

❄️ New #biomolecular #condensates added (total ⚪: 680)
❄️ #Protein - #condensate connections updated
❄️ Species attributes fixed 🤩

👀Check the current version here: cd-code.org
Join us as a contributor: cd-code.org/signup

🔊Calling the hive mind of the #Condensate Community: Join us in curating the CD-CODE!

Do you have a favorite condensate or have discovered one that’s not yet in CD-CODE?
We want your input and expertise!🧠

🔗Easy sign-up here: cd-code.org/signup
Add a new condensate ⤵️

☝️SG is one of the most populous condensate in CD-CODE, with human (cd-code.org/condensate/DEE…) and yeast (cd-code.org/condensate/E03…) proteomes being the most characterized up to date!

Are you a stress granule expert or enthusiast?
🦉Join us as a curator: cd-code.org/signup

Various species have different Stress Granule proteomes:
🔵Translationally stalled mRNAs,
🔵translation initiation factors,
🔵RNA-binding proteins, and
🔵non-RNA-binding proteins
are among the main constituents of SGs.

🚨October Condensate of the Month is Stress Granule!

#StressGranules (#SGs) are dynamically forming cytoplasmic condensates that form in response to various cellular stresses.
🤩In CD-CODE there are more than 10 species and more than 1300 #protein associations described for SGs.

📚Read more about +TIP body and its proteins:
doi.org/10.1371/journa…
nature.com/articles/s4155…
nature.com/articles/s4155…

These condensates concentrate proteins needed for growing tip of the #microtubule.
+TIP bodies have been described in...
...🐁mammalian cells (Wu et al., 2021),
...🧪S. pombe (Maan, Reese &Volkov et al., 2023),
...🧪S. cerevisiae (Meier, Farcas &Kumar et al., 2023 @LabBarral

💫September Condensate of the Month is +TIP body!💫

These #condensates form at the growing plus end of #microtubules, crucial for cell division and transport.🦠🧫 : cd-code.org/condensate/909…

Check out the protein composition of +TIPs in different organisms ⤵️

New Season 🍂🌿 - new #CDCODE release!
🥳Version 1.07 is here: cd-code.org

🌟We focused on improving #species attributions and updating missing #condensate features.

Help us with your condensate expertise!🧠
Join us to become a contributor: cd-code.org/signup

📚Read more about MARDO and its proteins:
doi.org/10.1093/nar/gk…
doi.org/10.1007/s00018…
science.org/doi/10.1126/sc…

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🔵MARDO is a #membraneless compartment that stores maternal mRNAs, important for early embryonic development.
ZAR1, an RNA-binding protein with an intrinsically disordered region (#IDR), plays a major role in MARDO assembly and facilitates clustering with #mitochondria.

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🌟Excited to introduce #MARDO as CD-CODE August "Condensate of the Month"!🌟

MARDO stands for Mitochondria-Associated RNA DOmain: cd-code.org/condensate/089…

💡It was first discovered and described by Cheng et al. @SchuhLab in #mammalian (mouse, bovine and human) #oocyte.

1/3🧵⤵️

📢We've just updated CD-CODE to v1.06!🎉

✨11 new #condensates integrated (total: 670)
✨ 21 new #proteins associated (total: 9672)
✨ 24 condensate-protein attributes updated

👀Check the current version here: cd-code.org

#DatabaseUpdate #NewRelease #Bioinformatics

Be a contributor and feature your research on CDcode!