I am thrilled to share that our work evaluating - deep breath - UVPD, ECD, AI-ECD, sceHCD (sceCID really), and EID for glycopeptides is out now!

pubs.acs.org/doi/10.1021/ac…
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The deadline (May 19th) is getting awfully close! Don't miss out.

brixenproteomics.org
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Shabaz Lab retweeted
RNA binding as an emerging regulatory dimension in the type I IFN response dlvr.it/TRr3sF
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Shabaz Lab retweeted
(JASMS) [ASAP] Investigating the Efficiency of Ultraviolet Photodissociation in Peptides Modified with N-Terminal UV-Absorbing Chromophores dlvr.it/TRjzlg (RSS) #MassSpecRSS #JASMS
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Shabaz Lab retweeted
Prosit-MultiFrag, a model predicting spectra for UVPD, ECD, ETciD & EID, is out 🚀
🔗 nature.com/articles/s4159…
Great collaboration with Shabaz Mohammed & Nikita Levin.

Try it via Koina koina.proteomicsdb.org and Oktoberfest: github.com/wilhelm-lab/ok…

#Proteomics #MassSpectrometry
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Shabaz Lab retweeted
A mass spectrometry platform integrates alternative fragmentation techniques into standard LC-MS workflows for broader community adoption.

nature.com/articles/s4159…
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🔬 New research from Oxford Chemistry advances proteomics by combining multiple fragmentation strategies within a single mass spectrometry platform.

Read more: chem.ox.ac.uk/article/combin…
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I am pleased to announce the final program for the EUPA Brixen Proteomics Summer School 2026 now also a @FEBSJournal Advanced Lecture Course
Thank you @thermofisher @EvosepBio Ionopticks @ReSyn_Bio @SIGNATOPE_GmbH Momentum Biotechnologies @bsi_peaks @biognosys for support!
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Turns out you can do cysteine profiling without lysing the cells first.

nature.com/articles/s4155…
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The Brixen Proteomics Summer School is back! Speaker list is already looking strong!
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We asked the question do solid particles have a role to play in the separation space within modern proteomics? Would these very small particles in short columns for fast gradients be a good idea for modern fast and sensitive MS? The answer was not no!

pubs.acs.org/doi/10.1021/ac…
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Shabaz Lab retweeted
Proud to announce my first publication is out in @PLOSPathogens ! Huge thanks to my co-first author Wael, @brennanlab, and @castello_lab. The paper explores how tick RNA-binding proteins respond to UUKV infection, you can find the paper here dx.plos.org/10.1371/journa…
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Shabaz Lab retweeted
🚨 New paper in @PLOSPathogens! 🚨 Together with @brennanlab, we mapped – for the first time – how tick RNA-binding proteins rewire during virus infection. 283 proteins changed activity, revealing key players in viral fitness. Read here: doi.org/10.1371/journa…
Proud to announce my first publication is out in @PLOSPathogens ! Huge thanks to my co-first author Wael, @brennanlab, and @castello_lab. The paper explores how tick RNA-binding proteins respond to UUKV infection, you can find the paper here dx.plos.org/10.1371/journa…
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We were just using NHS chemistry for some protein conjugation when we noticed some odd prominent side products. It turns out thio-nhs reagents (a major class of reagents) has some notable side reactions that happen all the time.

nature.com/articles/s4146…
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So Nikita really wanted to present his poster (ThP648) on the omnitrap at #ASMS2025. Well with the power of the internet he can! Visa be damned. Also he is fresh and not destroyed by all the vendor hospitality...
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Here's an LC story from our lab. Unlike a lot of stories with questions as titles this one is a maybe yes! Interesting for those high throughput proteomics people!

biorxiv.org/content/10.110…
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Deadline is fast approaching!
The Brixen summer school speaker list has been finalised. It's going to be another fantastic edition!
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Shabaz Lab retweeted
🚨🚨News: Interested in the proteome configuration that makes a cell permissive or hostile to virus infection? Why mRNA levels do not fully reflect the proteome status after interferon treatment? See the new paper from @castello_lab and Mohammed lab mcponline.org/article/S1535-…
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Shabaz Lab retweeted
We are excited to share our new Nature Methods paper describing the Chip-Tip workflow for single-cell proteomics identifying >5,000 proteins in single cells, enabling PTM analysis without enrichment and throughput of up to 120 single cell samples per day: rdcu.be/d6qJe
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