The Rullo Lab retweeted
Happy to share some recent work in the lab developing covalent peptides to reprogram antibody targeting function bpspubs.onlinelibrary.wiley.com/doi/epdf/10.11…
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Exciting to see recent work from the Rullo Lab highlighted in this @BritPharmSoc editorial on the re-emergence of covalent modulation in drug discovery! 🧪
Great to see covalent chemistry continuing to expand what’s possible in chemical biology and immunotherapy.
Great to see covalent chemistry continuing to expand what’s possible in chemical biology and immunotherapy.
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Very excited to share our group's latest research, published in @NatureComms, titled 'Mimicry of molecular glues using dual covalent chimeras'!
@LabRullo
Check out the full publication here: nature.com/articles/s4146…
@LabRullo
Check out the full publication here: nature.com/articles/s4146…
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The Rullo Lab retweeted
@LabRullo was cited in an independent blog on @ScienceMagazine website written by Derek Lowe titled “Induced Proximity in the Lab and in the Clinic”.
He is cited at the 4th link.
🔗science.org/content/blog-p…
Congratulations! 👏🥳
@RulloLab @machealthsci @MacDeptMed
He is cited at the 4th link.
🔗science.org/content/blog-p…
Congratulations! 👏🥳
@RulloLab @machealthsci @MacDeptMed
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The Rullo Lab retweeted
Brilliant contribution by @DASpiegel256 and co workers to induced proximity
Bifunctional Molecules That Induce Both Targeted Degradation and Transcytosis of Extracellular Proteins in Brain Cells | Journal of the American Chemical Society @Yale @YaleChem #Targeted #Degradation #Transcytosis #BrainCells #Proteins #Extracellular pubs.acs.org/doi/10.1021/ja…
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The Rullo Lab retweeted
Beautiful oxaziridine based oxidative approach to tryptophan labeling ! @christhechang and toste labs nature.com/articles/s4158…
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The Rullo Lab retweeted
Restricted Rotational Flexibility of the C5α-Methyl-Substituted Carbapenem NA-1-157 Leads to Potent Inhibition of the GES-5 Carbapenemase dlvr.it/T4YBjx
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The Rullo Lab retweeted
A beautifully written comprehensive review on the use of proximity induced chemistry to generate novel protein therapeutics by @Han_Xiao2016
cell.com/cell-chemical-…
cell.com/cell-chemical-…
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The Rullo Lab retweeted
Subunits of an E3 Ligase Complex as Degrons for Efficient Degradation of Cytosolic, Nuclear, and Membrane Proteins | ACS Synthetic Biology pubs.acs.org/doi/10.1021/ac…
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The Rullo Lab retweeted
Excited to present our work in covalent bifunctionals, for inducing cell-cell proximity in immunology ! #Covalent #proximity
trccc.org/annual-meeting
trccc.org/annual-meeting
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The Rullo Lab retweeted
Excited to return to beautiful Boston this Tuesday and see great colleagues working in covalent drug development and proximity inducing molecules!
covalent-drug-discovery.com/whats-on/speak…
covalent-drug-discovery.com/whats-on/speak…
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Check out our newest publication featuring @BenjaminLake15 ! Congratulations!
Happy to share our most recent contribution coupling covalency with carbohydrate binding for immune proximity induction.
pubs.acs.org/doi/full/10.10…
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The Rullo Lab retweeted
Join us tomorrow for WIP, featuring Annika Yardy from the Larche lab and Danielle Libera from the @jfekoenig @Jordana_Lab!
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The Rullo Lab retweeted
A must read
Exploration of the Tunability of BRD4 Degradation by DCAF16 Trans-labelling Covalent Glues dlvr.it/SxGnd3
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The Rullo Lab retweeted
Beautiful review @Han_Xiao2016 ! pdf.sciencedirectassets.com/313924/AIP/1-s…
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