🧠 OXT neurons in the PVH, visualized with LifeCanvas whole-brain clearing & immunolabeling and light-sheet imaging!

Join me at #SfN2026 to explore maternal oxytocin’s effects on offspring OXT neurons.

📍 PSTR342.08 | Nov 18, 4–5 PM

#Oxytocin #WholeBrainMapping #Neuroscience

🗓️ This Thursday we're kicking off our new webinar series with a deep dive into Dr. Ken Ishii's research on the neurobiology of addiction.

Join us to learn about building a whole-brain c-FOS quantification pipeline with LifeCanvas tools, and much more: bit.ly/472YiFV

📣 There's just over 1 week left to enter your SfN poster for inclusion in our poster guide and a chance at a $1000 travel award! Tell us about your poster: bit.ly/3Uapz6O #FluorescenceFriday

This tiny squid, captured on a #MegaSPIM light sheet microscope, is helping scientists understand how cephalopods detect changes in their aquatic environment. 🦑 Learn more: bit.ly/48lUArz

#MicroscopyMonday @carsten_wolff @MBLScience

What could you do with a Research Infrastructure award from the Massachusetts Life Sciences Center? 🤔 Earlier this year, Brandeis expanded their Light Microscopy Core Facility with a SmartSPIM light sheet microscope & SmartBatch+ active tissue processing system. @BrandeisImaging

Users at Brandeis and beyond have used the LifeCanvas pipeline to image intact samples from a variety of species including mice, rats, ferrets, zebra finches. Let's talk about how we can partner on a Research Infrastructure grant: bit.ly/4rELfUG

We got to talk about the essentials of sample prep for light sheet imaging at @WesternuWIN's Mesoscopic Integrated Neuroimaging Data (MIND) platform, including how to fast-track projects with their SmartBatch+ device. Thank you for hosting us! #LightSheet #TissueClearing

How does the cortex help regulate sleep & wakefulness? Researchers have ID'ed a sparse population of inhibitory neurons with unusually long axons which increase synchronization across multiple neocortical regions & promote sleep: bit.ly/47TH91Y #FluorescenceFriday

@JacobMRatliff @GeoffreyTerral @ArenskiV @NelsonPrezCata1 @neubertgabriela @liefefenno @HongkuiZeng @staci_sorensen @KarlDeisseroth @BatistaBritoLab

1 month left to apply for our #SfN26 travel award! We want to hear how you used the LifeCanvas 3D discovery pipeline in your poster. No form required – just post an image or video representing your research and tag us. We'll share + include your research in our SfN poster guide!

📹 This #FluorescenceFriday video is courtesy of @ShreyasMSurya, showing neurons projecting from the visual cortex to different parts of the brain. Directly generated neurons are shown in red, and indirectly generated neurons are shown in green.

This #FluorescenceFriday video from @KenIshii1223 shows mu-opioid receptor expressing cells (red) & c-FOS signal (green) in a mouse brain after exposure to acute morphine. Learn about the science behind this SmartSPIM light sheet data in our 11/5 webinar: bit.ly/4ri944r

Apps for @MALifeSciences's ARC awards are due 11/6! Thanks to this program, we're working with the Laboratory of Systems Pharmacology @ Harvard Med to develop high-plex 3D imaging methods to advance cancer research. We're always open to new collabs: bit.ly/4rELfUG

Is it really that easy to get 3D data from a 12 well plate? For #MicroscopyMonday, we thought we’d let #DALISPIM co-creator Nick Evans show you how our open-top light sheet microscope works, from plating samples to acquiring high-res data. Learn more: bit.ly/49pqjKd

Music credits to @nickminormajor7 as well!

#SmartSPIM light sheet microscopy is coming to Barcelona! We can't wait to show you how easy it is to capture hi-res 3D data throughout your entire sample, like this intact mouse brain and spinal cord, mouse duodenum, and rat heart. #FluorescenceFriday

Thank you for the featured data:
Mouse brain - @ShreyasMSurya (Huang lab, Duke)
Mouse duodenum - Dr. Hanan Mohammed (Ramadi lab, NYU Abu Dhabi)
Rat heart - Dr. Joshua Harrison (Birren lab, Brandeis)

@SPAOM5 @REMOABioimaging @PPBioImaging

Scientists at the @AllenInstitute have made major strides in understanding one of the brain’s key neuromodulatory systems. Read on to learn more and check out the open access paper... 🧵(1/5)

This work marks a significant advancement in our understanding of the noradrenaline system, with implications for how we treat mood and attention disorders. 📖 Read it here: nature.com/articles/s4158… (5/5)

@KanghoonJung @KentaM_Hagihara @Poofjunior @timjarsky @XiaoyinChenLab @adam_k_glaser @svoboda314 @yohisogai @JeremiahYCohen