My paper on statistical disease progression modeling in Alzheimer's disease has just been published in @FrontAIBigData. You can find it here doi.org/10.3389/fdata.… Want to try it out on your own data? Code can be found here github.com/larslau/progmod

🧠🧪✨Can we map the full timeline of biomarker changes in Alzheimer’s disease—from the earliest shifts (a decade before symptoms) to advanced dementia? Our new Brain paper says: Yes! Two large cohorts, one consistent story. (1/6)

🔗doi.org/10.1093/brain/…

Now, BioFINDER.
The patterns are strikingly consistent—timing of biomarker changes aligns closely with ADNI. (5/6)

Why does this matter?
Knowing when biomarkers change helps us stage disease and optimize timing for treatments—crucial for trials & patients. (6/6)
🙏 Thanks to all collaborators!
@NicholasAshton @SebastianPalmqv @OskarHansson9 @biofinder_study

“The arc of history is long, and it bends toward”

*flips through history book*

Oh. Oh no. Oh no no no

AI psychosis psychosis is rampant now

New paper & surprising result.
LLMs transmit traits to other models via hidden signals in data.
Datasets consisting only of 3-digit numbers can transmit a love for owls, or evil tendencies. 🧵

Our most important paper, out now! A massive international collaboration, led by @AlexisMoscoso9, featuring over 6500 visually assessed tau PET scans covering the #Alzheimers spectrum!

Thank you very much to the numerous contributors and collaborators who made this gem possible.

Strong title:

There is now something new under the sun: you can literally experience a completely new perceptual color that no one has ever seen before

biology is nothing but trouble

Always my favourite post at the beginning of the year:

Registration for our course “Biomarkers for neurodegenerative diseases” is now open!

This year’s edition takes place at @UCLIoN in central London on May 12-16.

biomarker-course.org

Excited to share the REAL AD design paper, now out in @alzdemjournals

The study has been live for 5 months, and we are elated and grateful that 5000 participants have already enrolled!

Stay turned for first results!

alz-journals.onlinelibrary.wiley.com/doi/10.1002/al…

A friendly reminder that our @ISTAART @DesignDataPIA All Member Meeting is happening tomorrow (Tuesday 09/10) at 2 p.m. CT!

Join us if you can 😎

@LarsRaket
@DrAnaCapuano
@mikemalekahmadi
@natggoncalves
@JetMJVonk
@ni_corv

I'm happy to share our paper on harmonizing tau PET in Alzheimer's disease that was just published in Alzheimer's & Dementia 🧠 📈 🚀
doi.org/10.1002/alz.13…
🧵[1/7]

This paper was the result of a monumental collaboration and data sharing effort in the Tau PET Harmonization Working Group led by the @CPathInstitute and includes representatives from academia, regulators, and industry from all over the world [6/7]

Thank you for the collaboration @AntoineLeuzy, @vincentDore2, @OskarHansson9, @susivak, and everyone else who contributed to this!! [7/7]