Dangliang Liu retweeted
Can we use RNA to insert kilobases of DNA into the human genome, opening up a new way to engineer cells or treat disease?
Excited to share our latest work turning a retrotransposon (a “jumping gene” with an RNA intermediate) from songbirds into a genome editing tool. 🧵 (1/7)
Excited to share our latest work turning a retrotransposon (a “jumping gene” with an RNA intermediate) from songbirds into a genome editing tool. 🧵 (1/7)
4
66
301
42,816
Dangliang Liu retweeted
Check out @cpnoct cool new study on the role of CCK neurons in the DRN for regulating satiation, out today @CellCellPress ! Excited to have contributed to this work.
Thrilled to share the latest work out of my lab at @CellCellPress on neuropeptidergic neurons in the dorsal raphe that regulate satiation. (cell.com/cell/fulltext/…). Led by Srikanth Chowdhury, Nachi Kamatkar, and Wendy Wang (from Xiao Wang's lab). Congrats to an incredible team!
2
2
7
1,500
Dangliang Liu retweeted
Synthesizing RNA can be as fun as LEGO puzzles! This work is co-led by my incredible colleagues @LDangliang and @AbhiAditham . Huge thanks to my supervisor @WangXiaoLab for such amazing ideas. We are also grateful for the editor, reviewers, and all collaborators along the way.
Chemical and topological design of multicapped mRNA and capped circular RNA to augment translation go.nature.com/47EXbfq
4
20
35
56,003
Dangliang Liu retweeted
Congratulations to Xiao Wang (@WangXiaoLab), the Cabot Assistant Professor of Chemistry and a Core Member of @broadinstitute, who has been promoted to Associate Professor with Tenure, effective July 1, 2024.
chemistry.mit.edu/chemistry-news…
chemistry.mit.edu/chemistry-news…
2
5
72
6,227
Dangliang Liu retweeted
Congratulations to Professor @WangXiaoLab, who has been honored as “Committed to Caring”. The Committed to Caring (C2C) program is a student-driven initiative that celebrates faculty members who have served as exceptional mentors to graduate students.
chemistry.mit.edu/chemistry-news…
chemistry.mit.edu/chemistry-news…
0
2
12
3,425
Dangliang Liu retweeted
Thrilled to see our work on chemically and topologically engineered mRNA online! Using a chemo-enzymatic approach, we introduced multiple end-modified polyA tails on a single mRNA to boost its stability and translatability overtime. nature.com/articles/s4158…
6
47
214
167,464
Dangliang Liu retweeted
Excited about my upcoming seminar on spatial transcriptomics and cell atlas! 🧬🔬 I will introduce the cool technologies to the general public. Join me as we delve into the fascinating world of cellular biology and explore spatial omic technologies @SITNBoston.
0
5
22
3,020
Dangliang Liu retweeted
Huge congrats to Hailing and the whole team, and thanks so much for the suggestions and help from the editor, reviewers, and colleagues through the long journey! Spatial atlas of the mouse central nervous system at molecular resolution: rdcu.be/dnaYu
Thrilled to see our work finally online! We utilized in situ spatial transcriptomic method STARmap PLUS to map 1.09 million cells in the adult mouse central nervous system at molecular resolution and identified previously unknown tissue architectures.
nature.com/articles/s4158…
10
23
192
59,153
Dangliang Liu retweeted
To fill the gap in cross-sample, cross-technology, and single-cell level spatial analyses, we created CAST to search, match, and visualize both similarities and differences of spatial molecular features across multiple samples. 1/5 @WangXiaoLab @tangzefang
Search and Match across Spatial Omics Samples at Single-cell Resolution biorxiv.org/cgi/content/sh… #biorxiv_bioinfo
3
31
107
24,142
Dangliang Liu retweeted
RIBOmap for spatially resolved single-cell translatomics is published today! Congrats to the whole team and thanks so much for the constructive feedback and great suggestion from the editor, reviewers, colleagues, and friends!
science.org/doi/10.1126/sc…
science.org/doi/10.1126/sc…
19
248
936
147,051
Dangliang Liu retweeted
Very humbled to share a bit of my own views about this beautiful work “spatial translatome mapping” from @WangXiaoLab and where the field is headed to in the future 😊
#spatialomics #spatialbiology #singlecell
Mapping RNA translation | Science science.org/doi/10.1126/sc…
#spatialomics #spatialbiology #singlecell
Mapping RNA translation | Science science.org/doi/10.1126/sc…
1
28
151
17,522
Dangliang Liu retweeted
Excited to share the collaboration with Prof. Morgan Sheng's lab and Genetech about using STARmap PLUS to dissect AD-associated gene programs and cell types with single-cell and spatial resolutions. Thanks to all the co-workers, editors, and reviewers! rdcu.be/c4SQr
STARmap PLUS, combining high-res spatial transcriptomics with protein detection in the same tissue section, reveals a cellular map of disease progression in an #Alzheimer's mouse model
New from @huzengHZ @jiahaoh511 @PixelDream_cn @WangXiaoLab et al.
nature.com/articles/s4159…
6
24
185
75,945