Glad to announce that Picasso v0.10.0 is out!
- ⚡️ GPUfit built in for localization (Windows)
- New fast fitting methods in SPINNA
- ThunderSTORM .csv import directly in Render
- Vastly extended API
- And many, many more…
Visit our page to find out: github.com/jungmannlab/pi…

In DNA-PAINT, nearby proteins create overlapping localizations. You may see two by eye, but analysis often misses them, wasting precious precision. G5M solves this. Now in @NatureComms: doi.org/10.1038/s41467… 1/7

G5M is implemented in Picasso since version 0.9.5: github.com/jungmannlab/pi…, although we always recommend using the most recent version! A short documentation: picassosr.readthedocs.io/en/latest/rend…. We advise reading the whole paper for best results! 6/7

We hope G5M helps push quantitative molecular mapping forward, and we’re excited to see the discoveries it enables. Thanks to @rafalkowalew, @SusanneReinhar3, @IBaudrexel, Shuhan Xu, @l_masu, for developing G5M and the rest of the @JungmannLab for testing and improving it. 7/7

Up to 15-fold improvement in protein labeling for DNA-PAINT 🧬🔬. We are excited to present our latest work published in @angew_chem! onlinelibrary.wiley.com/doi/10.1002/an…

Importantly, this workflow is broadly applicable and compatible with virtually any high off-rate binder. Many “bad” binders currently sitting in lab freezers may now become powerful imaging tools. 5/6

Big congrats to @CSteinek, @IBaudrexel, and Sebastian Strauss who led the project as well as other co-authors that contributed to this work!! 6/6

How do you scale super-resolution microscopy to dozens of proteins without linearly scaling imaging time?
We introduce Combi-PAINT: a combinatorial DNA-PAINT strategy that breaks the 1-target-per-round bottleneck of Exchange-PAINT: biorxiv.org/content/10.648…
1/5

#pictureofthemonth: The pic shows 30 different protein types with spatial resolution in a neuronal "atlas“ created with the imaging method SUM-PAINT.
Find out more: biochem.mpg.de/jungmann

November – institute calendar of @MPI_Biochem and @MPIforBI
Image by Eduard Unterauer

Now online: October 2025 Issue.

- Focus Issue on #biosensing
- DNA moiré superlattices
- Sugars at Ångström-resolution
- Solid-state #nanopores
- Non-aqueous Li #batteries
- Neuromorphic vision
- Peptide #hydrogels
- Deep learning for #LNPs & more.

nature.com/nnano/volumes/…

Our article "Ångström-resolution imaging of cell-surface glycans" on the cover of Nature Nanotechnology! 🤩 @NatureNano

nature.com/nnano/volumes/…

Thrilled to announce some big news!

I’ve been awarded a Wellcome Trust Early Career Award to establish my research as a Group Leader in the Glycosciences Program at the Institute of Biology and Experimental Medicine (IBYME) in Buenos Aires, Argentina, starting early 2026.