Before susceptibility results, can AI flag carbapenem-resistant A. baumannii? An ICU-based XGBoost model achieved AUC 0.878.
sciencedirect.com/science/articl…
@ISAC_world

Cefiderocol resistance before its clinical use in China? Among 443 carbapenem-resistant E. coli isolates, 23% were resistant, with ST167 and FhuA P50S implicated.
sciencedirect.com/science/articl…
@ISAC_world

How does hypervirulent K. pneumoniae worsen liver abscess? Hcp triggers macrophage HMGB1 release and RAGE-dependent endothelial pyroptosis.
sciencedirect.com/science/articl…
@ISAC_world

A peptide that helps restore antibiotic activity? FIRL perturbs BamA–BamD coupling, boosting polymyxin B in preclinical infection models.
sciencedirect.com/science/articl…
@ISAC_world

🧠🦠 Let's make AI our friend!
From predicting antimicrobial resistance and infections to supporting antibiotic stewardship and accelerating AI-driven drug discovery

📚 Explore recent advances: sciencedirect.com/special-issue/…

#AI #amr

@ISAC_world

🙌 A big thank you to our amazing reviewers!

As we reflect on Peer Review Week last week, we want to recognise the time and expertise you contribute to strengthening scientific research. 🔬

#PeerReviewWeek #Research

@ISAC_world

🔥Check out the Hot Topic: sciencedirect.com/science/articl…

Growing interest in phage therapy but important knowledge gaps and barriers remain...🦠

#PhageTherapy #AMR

@ISAC_world

⭐ Editor's Choice

🚨 The growing accumulation of antibiotic resistance is a serious concern!

New research finds ST1545 Klebsiella pneumoniae carrying genes that make them resistant to important antibiotics - carbapenems and tigecycline.

sciencedirect.com/science/articl…

@ISAC_world

📔New issue is out!

Featuring the latest research on phage therapy, novel antimicrobials, diagnostics & resistance mechanisms!

Explore more: sciencedirect.com/journal/intern…

@ISAC_world

🌟A fitting tribute to Professor Alasdair Macintosh Geddes—a pioneering infectious diseases physician and outstanding mentor

sciencedirect.com/science/articl…

@ISAC_world

🔥 Hot Topic
New antibiotics offer hope but are they reaching the patients who need them?
Access to newly approved antibacterials across Asian countries remains limited, with substantial approval delays
sciencedirect.com/science/articl…

#Antibiotics #InfectiousDiseases

@ISAC_world

🚀 Publishing antimicrobial research? Watch this.

ISAC and @ElsevierConnect bring together publishing experts and journal editors to share what makes a strong submission and what editors look for in high‑quality manuscripts.

youtu.be/xSR6JSJ3Hyg
@IJAA_ISAC @JGAR_ISAC

📢 New Issue | IJAA Volume 67, Issue 8
The latest issue is now online!

Featuring:

🔹 Reviews on antifungal prophylaxis and fluoroquinolone prophylaxis
🔹 Insights into novel therapeutics and machine learning
Explore more: sciencedirect.com/journal/intern…

@ISAC_world

🥳We're proud to share that the International Journal of Antimicrobial Agents has achieved a 2025 Impact Factor of 5.0, up from 4.6 in 2024.

A sincere thank you to our authors, reviewers, editors and readers!

@ISAC_world

New study: Stepwise cefiderocol exposure in NDM-producing Klebsiella pneumoniae selected recurrent baeS variants and reshaped iron uptake, porin expression, blaNDM-5, and biofilm responses.
sciencedirect.com/science/articl…
@ISAC_world

New IJAA study tracks in vivo tigecycline resistance in ST540 CRAB, revealing adeS N125S-driven AdeABC upregulation, collateral sensitivity to cefoperazone/sulbactam, and ICU transmission.
sciencedirect.com/science/articl…
@ISAC_world

MALDI-TOF MS combined with machine learning accurately predicts ceftriaxone resistance in Salmonella (ROC-AUC up to 0.924). This interpretable, web-based approach could accelerate targeted therapy and strengthen antimicrobial stewardship.
sciencedirect.com/science/articl…
@ISAC_world

New in IJAA (Vol.67, Issue 7): AI-guided AMR prediction, emerging CZA–cefiderocol cross-resistance, phage therapy advances, polymyxin B PK, and cefiderocol clinical evidence.
sciencedirect.com/journal/intern…
@ISAC_world

Using 5,239 Klebsiella pneumoniae genomes, a machine learning model accurately predicted multi-level antimicrobial resistance for 11 antibiotics (mean AUC >0.9), advancing precision therapy and AMR control.
sciencedirect.com/science/articl…
@ISAC_world

IJAA Volume 67 Issue 6 features the latest advances in AMR, AI-guided infection prediction, CRKP resistance, phage therapy, anti-biofilm strategies, and antimicrobial PK/PD optimization.
sciencedirect.com/journal/intern…
@ISAC_world