How does an embryo turn a sequence in time into a pattern in space?
Join us for an upcoming webinar with Professor @ezzatelsherif of @UTRGVResearch, exploring how sequential HCR™ imaging can reveal the relationship between temporal gene expression and spatial pattern formation embryos.
Professor El-Sherif will share an approach for visualizing up to ten patterning genes within the same embryo and discuss how intronic and exonic probes can provide insight into transcriptional dynamics in fixed samples.
🗓️ Thursday, December 3
🕗 10:00 AM PT
Register here: my.demio.com/ref/HXtNMZEOdC…
Join us for an upcoming webinar with Professor @ezzatelsherif of @UTRGVResearch, exploring how sequential HCR™ imaging can reveal the relationship between temporal gene expression and spatial pattern formation embryos.
Professor El-Sherif will share an approach for visualizing up to ten patterning genes within the same embryo and discuss how intronic and exonic probes can provide insight into transcriptional dynamics in fixed samples.
🗓️ Thursday, December 3
🕗 10:00 AM PT
Register here: my.demio.com/ref/HXtNMZEOdC…
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Looking for a simpler way to run HCR™ Pro RNA-ISH on the DISCOVERY ULTRA platform?
HCR™ Pro Detect kits are available in pre-filled, ready-to-use (RTU) dispensers, helping reduce hands-on time and manual steps while supporting greater consistency from run to run.
Streamline kflow without compromising performance.
Learn more: hcrimaging.com/articles/rtu-d…
Order today: store.hcrimaging.com/new-kit/rna-ish
HCR™ Pro Detect kits are available in pre-filled, ready-to-use (RTU) dispensers, helping reduce hands-on time and manual steps while supporting greater consistency from run to run.
Streamline kflow without compromising performance.
Learn more: hcrimaging.com/articles/rtu-d…
Order today: store.hcrimaging.com/new-kit/rna-ish
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What a turnout for our latest #MIwebinars session!
We explored a streamlined HCR™ Pro RNA-CISH workflow for ultra-sensitive detection and rapid screening of low-abundance RNA targets in whole-mount Xenopus embryos.
Special thanks to Professor Douglas Houston at the University research and experience with #HCRtechnology.
🔬 Coming up next: Professor @ezzatelsherif of the @UTRGVResearch. Stay tuned for details!
We explored a streamlined HCR™ Pro RNA-CISH workflow for ultra-sensitive detection and rapid screening of low-abundance RNA targets in whole-mount Xenopus embryos.
Special thanks to Professor Douglas Houston at the University research and experience with #HCRtechnology.
🔬 Coming up next: Professor @ezzatelsherif of the @UTRGVResearch. Stay tuned for details!
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We’re expanding the HCR™ Gold IF portfolio with HCR™ HiFi Secondaries!
Designed for secondary antibody-based IF, HCR™ HiFi Secondaries deliver high-performance signal amplification for a broad range of primary antibodies, including those raised in chicken, goat, and sheep.
condaries and HCR™ HiFi Encoders now available, you can choose the multiplexing strategy that best fits your experiment. For RNA and protein co-detection, either approach can also be combined with HCR™ Gold RNA-FISH in the same sample.
🔬Explore HCR™ HiFi Secondaries: store.molecularinstruments.com/new-kit/gold/i…
Designed for secondary antibody-based IF, HCR™ HiFi Secondaries deliver high-performance signal amplification for a broad range of primary antibodies, including those raised in chicken, goat, and sheep.
condaries and HCR™ HiFi Encoders now available, you can choose the multiplexing strategy that best fits your experiment. For RNA and protein co-detection, either approach can also be combined with HCR™ Gold RNA-FISH in the same sample.
🔬Explore HCR™ HiFi Secondaries: store.molecularinstruments.com/new-kit/gold/i…
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Last call to register! Our webinar with Professor Douglas Houston from the University of Iowa is coming up soon.
Learn how HCR™ Pro RNA-CISH and HCR™ Gold RNA-FISH can help researchers balance sensitivity, readout, and multiplexing needs in whole-mount embryos.
🗓️ Thursday, / 10:00 AM CT
Register now: my.demio.com/ref/XCVLmHOnaJ…
Learn how HCR™ Pro RNA-CISH and HCR™ Gold RNA-FISH can help researchers balance sensitivity, readout, and multiplexing needs in whole-mount embryos.
🗓️ Thursday, / 10:00 AM CT
Register now: my.demio.com/ref/XCVLmHOnaJ…
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Setting up HCR™ workflows in a new lab?
The New Lab Starter Program is designed to make getting started a little easier. Eligible labs receive six months of reduced pricing for HCR™ Gold and Pro workflows.
Interested in learning more? Contact ruments.com for program details and to see whether your lab qualifies.
The New Lab Starter Program is designed to make getting started a little easier. Eligible labs receive six months of reduced pricing for HCR™ Gold and Pro workflows.
Interested in learning more? Contact ruments.com for program details and to see whether your lab qualifies.
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Upcoming Webinar: A case study in Xenopus using HCR™ Pro RNA-CISH and HCR™ Gold RNA-FISH to maximize sensitivity and multiplex capabilities
Different experimental questions can call for different readouts: high-sensitivity chromogenic detection for low-abundance targets, and imaging for quantifying expression across multiple targets.
Join Professor Douglas Houston from the @uiowa to see how HCR™ Pro RNA-CISH can support ultra-sensitive chromogenic detection and brightfield imaging in whole-mount embryos, and how HCR™ Gold RNA-FISH can complement that workflow for high-resolution, quantitative analysis.
🗓️ Thursday, October 29
🕗 8:00 AM PT / 10:00 AM CT
Register today: my.demio.com/ref/XCVLmHOnaJ…
Different experimental questions can call for different readouts: high-sensitivity chromogenic detection for low-abundance targets, and imaging for quantifying expression across multiple targets.
Join Professor Douglas Houston from the @uiowa to see how HCR™ Pro RNA-CISH can support ultra-sensitive chromogenic detection and brightfield imaging in whole-mount embryos, and how HCR™ Gold RNA-FISH can complement that workflow for high-resolution, quantitative analysis.
🗓️ Thursday, October 29
🕗 8:00 AM PT / 10:00 AM CT
Register today: my.demio.com/ref/XCVLmHOnaJ…
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We’re heading to Woods Hole, MA for the 12th Aquatic Models of Human Disease Conference at @MBLScience!
Join Aneesh Acharya and Megan Le on Monday, October 19, for our scientific session exploring how the HCR™ platform can support research across aquatic model organisms and ur questions, share your research and use cases, and stop by our table to connect with the team.
We look forward to seeing you there!
Join Aneesh Acharya and Megan Le on Monday, October 19, for our scientific session exploring how the HCR™ platform can support research across aquatic model organisms and ur questions, share your research and use cases, and stop by our table to connect with the team.
We look forward to seeing you there!
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Behind every breast cancer awareness campaign are researchers, pathologists, and clinicians helping us better understand the disease.
This month, we’re taking a moment to recognize the science, care, and dedication behind that progress.
We’re honored to support the research d deeper insight and better outcomes.
This month, we’re taking a moment to recognize the science, care, and dedication behind that progress.
We’re honored to support the research d deeper insight and better outcomes.
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How can researchers maximize sensitivity when detecting low-abundance RNA targets in whole-mount embryos?
In our upcoming webinar, Prof. Douglas Houston from the University of Iowa will share how manual HCR™ Pro RNA-CISH can support brightfield screening of low-abundance RNA Xenopus embryos.
He’ll also discuss how HCR™ Gold RNA-FISH can help move promising observations into high-resolution, multiplexed fluorescent analysis, plus approaches for combining RNA detection with immunostaining.
🗓️ Thursday, October 29
🕗 8:00 AM PT / 10:00 AM CT
Register here: my.demio.com/ref/XCVLmHOnaJ…
In our upcoming webinar, Prof. Douglas Houston from the University of Iowa will share how manual HCR™ Pro RNA-CISH can support brightfield screening of low-abundance RNA Xenopus embryos.
He’ll also discuss how HCR™ Gold RNA-FISH can help move promising observations into high-resolution, multiplexed fluorescent analysis, plus approaches for combining RNA detection with immunostaining.
🗓️ Thursday, October 29
🕗 8:00 AM PT / 10:00 AM CT
Register here: my.demio.com/ref/XCVLmHOnaJ…
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Introducing HCR™ HiFi Secondaries!
We’re extending our proprietary HiFi background suppression technology to HCR™ HiFi Secondaries, giving researchers two powerful ways to multiplex protein labeling:
• HCR™ HiFi Encoders enable straightforward multiplexing with same-species econdaries enable best-in-class amplification for the broadest range of primaries, including those raised in chicken, rat, goat, and other host species
Both can be combined in the same IF assay and are natively compatible with HCR™ Gold RNA-FISH for RNA + protein co-detection, allowing you to select the best approach for your research.
Shop HCR™ Gold 2°IF today: store.molecularinstruments.com/new-kit/gold/i…
We’re extending our proprietary HiFi background suppression technology to HCR™ HiFi Secondaries, giving researchers two powerful ways to multiplex protein labeling:
• HCR™ HiFi Encoders enable straightforward multiplexing with same-species econdaries enable best-in-class amplification for the broadest range of primaries, including those raised in chicken, rat, goat, and other host species
Both can be combined in the same IF assay and are natively compatible with HCR™ Gold RNA-FISH for RNA + protein co-detection, allowing you to select the best approach for your research.
Shop HCR™ Gold 2°IF today: store.molecularinstruments.com/new-kit/gold/i…
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Up next: SoCal SOT!
The MI team is headed to @ionispharma tomorrow for the Southern California @SOToxicology Fall Meeting!
At the event, we’ll focus on an important step that comes before AI-driven image analysis: generating high-quality, interpretable images. Our presentation ng approaches for short RNA targets, including siRNAs and oligonucleotide payloads in AOCs, alongside multiplex immunofluorescence with HCR™ HiFi Encoders.
If you’re attending, stop by and say hello. We’d love to connect!
The MI team is headed to @ionispharma tomorrow for the Southern California @SOToxicology Fall Meeting!
At the event, we’ll focus on an important step that comes before AI-driven image analysis: generating high-quality, interpretable images. Our presentation ng approaches for short RNA targets, including siRNAs and oligonucleotide payloads in AOCs, alongside multiplex immunofluorescence with HCR™ HiFi Encoders.
If you’re attending, stop by and say hello. We’d love to connect!
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Join us for an upcoming webinar with Professor Douglas Houston from the @uiowa!
Prof. Houston will share a Xenopus case study exploring how HCR™ Pro RNA-CISH and HCR™ Gold RNA-FISH can be used together to balance extreme-sensitivity RNA detection with multiplexed fluorescent will cover ultra-sensitive chromogenic detection of low-abundance RNA targets in whole-mount embryos, along with approaches for RNA and protein co-detection.
🗓️ Thursday, October 29
🕗 8:00 AM PT / 10:00 AM CT
Register here: my.demio.com/ref/XCVLmHOnaJ…
Prof. Houston will share a Xenopus case study exploring how HCR™ Pro RNA-CISH and HCR™ Gold RNA-FISH can be used together to balance extreme-sensitivity RNA detection with multiplexed fluorescent will cover ultra-sensitive chromogenic detection of low-abundance RNA targets in whole-mount embryos, along with approaches for RNA and protein co-detection.
🗓️ Thursday, October 29
🕗 8:00 AM PT / 10:00 AM CT
Register here: my.demio.com/ref/XCVLmHOnaJ…
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More fluorophore options, more ways to build your HCR™ Gold assay.
HCR™ Gold Amplifiers are now available with 488, 546, 594, and 647 labels across every X system, giving you more flexibility when designing panels around your targets and imaging channels.
Ready to explore the xpanded amplifier selection today.
🛒 store.molecularinstruments.com/new-kit/gold/r…
HCR™ Gold Amplifiers are now available with 488, 546, 594, and 647 labels across every X system, giving you more flexibility when designing panels around your targets and imaging channels.
Ready to explore the xpanded amplifier selection today.
🛒 store.molecularinstruments.com/new-kit/gold/r…
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Yesterday, we hosted a webinar on “Multimodal alignments of in vivo imaging and spatial biology datasets at cellular resolution.”
A special thank-you to our wonderful speakers, @jxqjim and @LunWangm from @Stanford, for sharing how TRU-FACT integrates #HCRtechnology with connectivity data to link cellular activity, molecular identity, and projection targets.
We enjoyed this installment of HCR™ webinars and look forward to sharing more soon!
A special thank-you to our wonderful speakers, @jxqjim and @LunWangm from @Stanford, for sharing how TRU-FACT integrates #HCRtechnology with connectivity data to link cellular activity, molecular identity, and projection targets.
We enjoyed this installment of HCR™ webinars and look forward to sharing more soon!
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We’re heading to the @NS4Histotech Convention this weekend!
Come say hello at Booth #620 to connect with our team and join us for our workshop, “Translating Spatial RNA Biomarkers into Point-of-Care Lateral Flow Assays,” where we’ll highlight how #HCRtechnology can be adapted ion.
🗓️ Sept. 29
🕤 9:15–10:15 AM
Come say hello at Booth #620 to connect with our team and join us for our workshop, “Translating Spatial RNA Biomarkers into Point-of-Care Lateral Flow Assays,” where we’ll highlight how #HCRtechnology can be adapted ion.
🗓️ Sept. 29
🕤 9:15–10:15 AM
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We're excited to introduce Slide Wash Chambers for manual slide-based workflows!
Orders that include HCR™ Wash Buffers for tissue sections or cells on a slide will now receive two complimentary Slide Wash Chambers. Each chamber provides a lower-volume alternative to traditional ing reduce wash buffer use during manual assays.
Add HCR™ Wash Buffers to your next order to receive yours: molecularinstruments.com/shop
Orders that include HCR™ Wash Buffers for tissue sections or cells on a slide will now receive two complimentary Slide Wash Chambers. Each chamber provides a lower-volume alternative to traditional ing reduce wash buffer use during manual assays.
Add HCR™ Wash Buffers to your next order to receive yours: molecularinstruments.com/shop
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What a fantastic time at the German Fish Meeting!
It’s always exciting to see #HCRtechnology used in such a wide range of model systems. This week, it was especially fun to hear about so many fish models, including zebrafish, cavefish, and more.
Thank you to everyone who you’re using HCR™ workflows in your research. We loved hearing about the variety of applications across the fish model community.
Next up for the MI team: @NS4Histotech Convention!
It’s always exciting to see #HCRtechnology used in such a wide range of model systems. This week, it was especially fun to hear about so many fish models, including zebrafish, cavefish, and more.
Thank you to everyone who you’re using HCR™ workflows in your research. We loved hearing about the variety of applications across the fish model community.
Next up for the MI team: @NS4Histotech Convention!
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San Antonio, we’ll see you soon!
The MI team will be at the National Society for Histotechnology Convention. Stop by Booth #620 to talk about HCR™ workflows, RNA and protein imaging, and how our team can support your research goals.
Don’t miss our workshop, “Translating into Point-of-Care Lateral Flow Assays,” for a practical look at adapting #HCRimaging for lateral flow detection.
🗓️ Tuesday, September 29
🕤 9:15–10:15 AM
See you there!
The MI team will be at the National Society for Histotechnology Convention. Stop by Booth #620 to talk about HCR™ workflows, RNA and protein imaging, and how our team can support your research goals.
Don’t miss our workshop, “Translating into Point-of-Care Lateral Flow Assays,” for a practical look at adapting #HCRimaging for lateral flow detection.
🗓️ Tuesday, September 29
🕤 9:15–10:15 AM
See you there!
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More fluorophore flexibility for HCR™ Gold is here!
HCR™ Gold Amplifiers with 488, 546, 594, and 647 labels are now available for every X system, giving you more flexibility to configure assays around your specific target panel and imaging setup.
All new catalog amplifiers on our webstore.
Order here: store.molecularinstruments.com/new-kit/gold/r…
HCR™ Gold Amplifiers with 488, 546, 594, and 647 labels are now available for every X system, giving you more flexibility to configure assays around your specific target panel and imaging setup.
All new catalog amplifiers on our webstore.
Order here: store.molecularinstruments.com/new-kit/gold/r…
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