Pablo GUARDADO-CALVO retweeted
1/3 🚀 We’re excited to introduce CryoPilot!
Two AI agents take cryo-EM data from raw images to refined atomic models—making decisions, testing strategies, and keeping the analysis moving while you focus on your science!
biorxiv.org/content/10.648…
#CryoEM #AIAgents
Two AI agents take cryo-EM data from raw images to refined atomic models—making decisions, testing strategies, and keeping the analysis moving while you focus on your science!
biorxiv.org/content/10.648…
#CryoEM #AIAgents
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Pablo GUARDADO-CALVO retweeted
¿Cuál es el legado de un investigador? Sus descubrimientos, seguro. Pero también haber contribuido a formar la siguiente generación de científicos. Orgulloso de concesión Premio Nacional de Investigación @CienciaGob para Jóvenes en Medicina y Ciencias de la Salud a Biola Javierre esis doctoral codirigí con @eballestar entre @CNIOStopCancer y @idibell_cat. ¡Sus hallazgos sobre cómo la #cromatina se organiza en #3D son preciosos!
cadenaser.com/aragon/2026/07…
cadenaser.com/aragon/2026/07…
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Pablo GUARDADO-CALVO retweeted
✨ WE ARE HIRING! ✨ Are you a Crystallographer interested in viruses? 💎 The Kreylab is looking for a motivated Postdoc to join our mission in fighting the Hepatitis E Virus! 🦠
Help us design antiviral inhibitors using structural biology. 🚀
b-ite.com/recruitingmana…
Help us design antiviral inhibitors using structural biology. 🚀
b-ite.com/recruitingmana…
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Pablo GUARDADO-CALVO retweeted
#PhD studentship in my lab at @ucl on #AI + Structural #Bioinformatics for predicting pathogen-host protein interactions
📅 Application deadline: 12 July 2026
More info/apply:
ucl.ac.uk/work-at-ucl/se…
DM me for informal enquiries. Please share!
#MachineLearning
📅 Application deadline: 12 July 2026
More info/apply:
ucl.ac.uk/work-at-ucl/se…
DM me for informal enquiries. Please share!
#MachineLearning
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Pablo GUARDADO-CALVO retweeted
The amazing Robert Krause from @MedUniGraz will talk about 'Clinical Aspects of Hanta Virus Infections' at our next LBI SOAP One Health Seminar.
When: Wednesday, May 27th, 3pm CET
Where? Online. Register here: soap.lbg.ac.at/events/one-hea…
When: Wednesday, May 27th, 3pm CET
Where? Online. Register here: soap.lbg.ac.at/events/one-hea…
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Pablo GUARDADO-CALVO retweeted
Vaccine development for hantaviruses is not that easy. Inactivated vaccines are hard to make (but exist for another strain in China and Korea), its not clear that DNA vaccines would work and recombinant protein vaccines may be tough. mRNA is likely a good solution.
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Pablo GUARDADO-CALVO retweeted
🧬 Blocking poxvirus fusion = blocking infection.
With #ISIDORe, Guardado-Calvo’s team solved a fusion complex subunit bound to inhibitor & generated nanobodies targeting 4 subunits.
Next: test neutralization & solve top structures.
#Poxvirus #Antivirals #CryoEM #Nanobodies
With #ISIDORe, Guardado-Calvo’s team solved a fusion complex subunit bound to inhibitor & generated nanobodies targeting 4 subunits.
Next: test neutralization & solve top structures.
#Poxvirus #Antivirals #CryoEM #Nanobodies
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Pablo GUARDADO-CALVO retweeted
Another great short essay, by Paul Nurse, 2021:
"Theorizing should be encouraged, and theories should be included in experimental papers to put data in context."
"Theorizing should be encouraged, and theories should be included in experimental papers to put data in context."
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Pablo GUARDADO-CALVO retweeted
Thrilled to share that our @freund_lab work on the antibody response against #MPXV A28 protein is now on @NatureComms !
Huge thanks to @Guardado_Calvo, @Virus_Immunity, @OrenKobiler, @LabAdler, @Fishelsonlab, @SouraskyMedCtr and @TAUMedFaculty.
More in🧵
nature.com/articles/s4146…
Huge thanks to @Guardado_Calvo, @Virus_Immunity, @OrenKobiler, @LabAdler, @Fishelsonlab, @SouraskyMedCtr and @TAUMedFaculty.
More in🧵
nature.com/articles/s4146…
1/11 New preprint alert! Our latest @freund_lab study in which we dissect how the immune system fights #Mpox and identify potent human neutralizing monoclonal antibodies (#mAbs) that target a novel key viral protein, #MpoxA28. Now on biorxiv: biorxiv.org/content/10.110…🧵
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Pablo GUARDADO-CALVO retweeted
Francis Mojica se empecina en buscar qué demonios son esas secuencias repetidas de las bacterias de las lagunas de Santa Pola… y unos años después ha cambiado el mundo…
Una de las 7 maravillas que destaca Nature.
¿Es o no una maravilla la ciencia?
nature.com/articles/d4158…
Una de las 7 maravillas que destaca Nature.
¿Es o no una maravilla la ciencia?
nature.com/articles/d4158…
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Pablo GUARDADO-CALVO retweeted
The California #mpox cases mark the FIRST LOCALLY ACQUIRED Clade Ib infections in the U.S. Researchers are now closely monitoring for signs of household or community spread and severe outcomes. Thank you @JohnsHopkinsSPH for this. linkedin.com/posts/drmelvin…
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Pablo GUARDADO-CALVO retweeted
BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 It started from my frustration with the depressing effect that the current publishing system has self, my team, and pretty much every scientist I know (maybe you’ve noticed from my stupid jokes… :) I was exhausted of dealing with the huge delays, reviewers that can be abusive, and how arbitrary it all is. Unfortunately, the most important factors are often WHO your reviewers are and who YOU are... It’s clear we need alternatives or at least ways to improve the situation. So, together with a really special and talented team we worked to develop this idea into “qed” a platform where you can get CONSTRUCTIVE feedback on your own work or CRITICALLY assess other people’s papers. It can be a real difference maker if many of you join us (thousands have tried it already, but today we release a NEW and much stronger version ;) Let’s harness qed to put the power back in the scientists’ hands, to do, to read & to publish science on our own terms. I’m dying for you to TRY IT, and it’s very simple - just drop a paper (the link to the website is in the replies👇) - it’s completely secure, private, and free, and you get results fast. Please show your support, SHARE, tell your friends, and let’s be the revolution 🫵!
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Pablo GUARDADO-CALVO retweeted
“Estoy hecho un Ferrari en comparación con lo que era hace dos meses”, expresó Gonzalo Moratorio en la 5ª edición de la gala Reconocimiento a la Ciencia y la Salud del Uruguay. Además, el virólogo subrayó la importancia de apoyar a la ciencia.
👉 m.uy/uc938354
👉 m.uy/uc938354
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Pablo GUARDADO-CALVO retweeted
Enhanced mouse virulence of mpox virus clade Ib over clade IIb despite genomic changes caused by human-to-human transmission biorxiv.org/content/10.110… #biorxiv_micrbio
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Pablo GUARDADO-CALVO retweeted
#YNoPasaNada, solo me apetece quemar las consejerias de educación y sanidad de la Junta de Andalucía. El derecho a una educación inclusiva recae en las administraciones no puede ser que no pueda estar escolarizado por falta de una enfermera escolar. ¡Basta! @colectivoDIME
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Pablo GUARDADO-CALVO retweeted
🧵 Tras una semana en CTI y 3 meses de rehabilitación, estamos de vuelta!
Nuestro estudio en @MolBioEvol muestra cómo la proteína antiviral ZAP (Zinc Antiviral Protein) ha impactado en la composición genómica de muchos virus ARN 👇
Nuestro estudio en @MolBioEvol muestra cómo la proteína antiviral ZAP (Zinc Antiviral Protein) ha impactado en la composición genómica de muchos virus ARN 👇
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Pablo GUARDADO-CALVO retweeted
🧵 After one week in ICU and three months in rehab, little by little I’m back.
I’m excited to share our new study in @MolBioEvol on how the antiviral protein Zinc Antiviral Protein (ZAP) has shaped the genomic composition of many RNA viruses 👇
I’m excited to share our new study in @MolBioEvol on how the antiviral protein Zinc Antiviral Protein (ZAP) has shaped the genomic composition of many RNA viruses 👇
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Pablo GUARDADO-CALVO retweeted
Now online! Structural basis of poxvirus fusion regulation and anti-A16/G9 antibody-mediated neutralization and protection dlvr.it/TMkqLJ
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