Aleksandra Filipovska retweeted
Is “Integrative #MitochondrialMedicine” Becoming a Field?
Find out on the MitoBlog with @KeystoneSymp organizers @mitopinionated & @FilipovskaLab on the conference, @ARIA_research & Shark Tank session!
mitoworld.org/is-integrative…
hubs.la/Q04xYBXn0
#mitoscientists #mitochondria
Find out on the MitoBlog with @KeystoneSymp organizers @mitopinionated & @FilipovskaLab on the conference, @ARIA_research & Shark Tank session!
mitoworld.org/is-integrative…
hubs.la/Q04xYBXn0
#mitoscientists #mitochondria
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Aleksandra Filipovska retweeted
Happy to share our new preprint on the structure of the human mitochondrial RNA degradosome, a central player in organellar RNA metabolism!
Work led by graduate student @paulafprado in our lab.
biorxiv.org/content/10.648…
🧵 1/9
Work led by graduate student @paulafprado in our lab.
biorxiv.org/content/10.648…
🧵 1/9
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We’re hiring! 🧬
Exciting opportunities in mitochondrial genome engineering and therapies for mitochondrial disease with @FilipovskaLab in sunny Western Australia ☀️
and at our biotech CodeBreakers
Apply: au.seek.com/job/94426759
#Mitochondria #GenomeEngineering #Postdoc #Biotech
Exciting opportunities in mitochondrial genome engineering and therapies for mitochondrial disease with @FilipovskaLab in sunny Western Australia ☀️
and at our biotech CodeBreakers
Apply: au.seek.com/job/94426759
#Mitochondria #GenomeEngineering #Postdoc #Biotech
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Aleksandra Filipovska retweeted
Congratulations to SWAN Genomics, Number 8 bio, @HydgeneR and All G on securing funding from a $4.75 million BioSciences Fund, designed to help companies bring their technologies to market. 🎉
➡️ Read our story: coesb.com.au/synbio-win-for…
@arc_gov_au
➡️ Read our story: coesb.com.au/synbio-win-for…
@arc_gov_au
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Aleksandra Filipovska retweeted
Great to see this work led by @LDorstyn @CCB_Research funded by @nhmrc and many years in the making now out: Caspase-2 deficiency drives pathogenic liver polyploidy and increases age-associated hepatocellular carcinoma in mice | Science Advances science.org/doi/10.1126/sc…
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Aleksandra Filipovska retweeted
Sun, surf and scientific talks 😎
Centre Director Ian Paulsen and COO J-L Heylen joined CoESB researchers from our @uwanews and @CurtinUni nodes for their annual Theme 2 (Synthetic Organelles) Retreat on Rottnest Island in sunny WA 🌊☀️ @TheRackhamLab @FilipovskaLab @arc_gov_au
Centre Director Ian Paulsen and COO J-L Heylen joined CoESB researchers from our @uwanews and @CurtinUni nodes for their annual Theme 2 (Synthetic Organelles) Retreat on Rottnest Island in sunny WA 🌊☀️ @TheRackhamLab @FilipovskaLab @arc_gov_au
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Aleksandra Filipovska retweeted
Our story about FASTKD5 is now published at @NAR_Open. It was an amazing collaboration with @hauke_hillen and @Antonio41949078 labs.
doi.org/10.1093/nar/gk…
FASTKD5 processes mitochondrial pre-mRNAs at non-canonical cleavage sites
doi.org/10.1093/nar/gk…
FASTKD5 processes mitochondrial pre-mRNAs at non-canonical cleavage sites
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Aleksandra Filipovska retweeted
This poster is a must have for labs working on #MCS! A guide through the work of so many outstanding labs (apologies if we did not cite your work). Hang it in your office or lab, it will please your eyes and inspire your mind! Kudos to the driving force Antigoni Diokmetzidou! -LS
In their Cell Science at a Glance article, Antigoni Diokmetzidou & Luca Scorrano @LabScorrano summarise the mitochondrial contacts characterised in mammals, the mechanisms underlying their formation, and their principal functions.
journals.biologists.com/jcs/article/13…
#JCSMitoSI #OpenAccess
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Aleksandra Filipovska retweeted
Dysfunctional mitochondria trap proteins in the intermembrane space | The EMBO Journal embopress.org/doi/full/10.10…
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It takes two to TANGO2!
TANGO2 binds the heat shock protein crystallin alpha B to prevent aggregation of the intermediate filament desmin and its loss models TANGO2-deficiency disorder
Many thanks to our team, collaborators and reviewers.
rdcu.be/epI3p
#metabolism
TANGO2 binds the heat shock protein crystallin alpha B to prevent aggregation of the intermediate filament desmin and its loss models TANGO2-deficiency disorder
Many thanks to our team, collaborators and reviewers.
rdcu.be/epI3p
#metabolism
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Aleksandra Filipovska retweeted
Silencing mitochondrial gene expression in living cells | Science science.org/doi/10.1126/sc…. Wonderful that our paper is out now in Science. A big thanks to LD Cruz-Zaragoza and the team, @warscheidlab & @JakobsLab .
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Aleksandra Filipovska retweeted
📢 Hunter Meeting abstract submissions close 5pm AEST today!
@ANZSCDB is proud to have joined forces with the Hunter Meeting 2025.
Please encourage your colleagues, postdocs and students to submit their abstracts today!
Link: huntermeeting.org.au/abstract-submi…
@ANZSCDB is proud to have joined forces with the Hunter Meeting 2025.
Please encourage your colleagues, postdocs and students to submit their abstracts today!
Link: huntermeeting.org.au/abstract-submi…
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Aleksandra Filipovska retweeted
Ready to make breakthroughs in gene editing and mitochondrial biology in sunny Western Australia?
Join our vibrant team as a Research Associate or Research Fellow. Expertise in cryo-EM, cell imaging, or mammalian genetic screens is highly desirable
staff.curtin.edu.au/explore-career…
Join our vibrant team as a Research Associate or Research Fellow. Expertise in cryo-EM, cell imaging, or mammalian genetic screens is highly desirable
staff.curtin.edu.au/explore-career…
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Aleksandra Filipovska retweeted
The peer-reviewed version of our paper on human tRNA 3' processing is now published in @NatureSMB. Many thanks to the reviewers for their constructive comments!
nature.com/articles/s4159…
See also the very nice related work by @BMartinHallberg @no1gv: embopress.org/doi/full/10.10…
nature.com/articles/s4159…
See also the very nice related work by @BMartinHallberg @no1gv: embopress.org/doi/full/10.10…
Happy to share a new preprint, in which we describe the mechanism of human tRNA 3' processing. We show why the RNase Z ELAC2 acts as a monomer in the nucleus, but forms a multi-subunit complex in mitochondria. Plase see 🧵 by @BhattaArjun2p for details!
biorxiv.org/content/10.110…
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New structural and functional analyses show that FASTKD4 supports non-canonical RNA processing and MT-ND3 mRNA stability. Thanks to all authors for their contributions and the reviewers for their kind advice!
academic.oup.com/nar/article/do…
#RNA
#mitochondria
#mtDNA
academic.oup.com/nar/article/do…
#RNA
#mitochondria
#mtDNA
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Aleksandra Filipovska retweeted
Update! We outline AIVE, an AI method for volume EM data. We show the benefits of AIVE for reconstructing your FIB-SEM data, reveal some fascinating cell biology, and define intrusions as a new form of mitochondrial contact.
biorxiv.org/content/10.110…
Muscle mito nanotunnels 1/3🧵
biorxiv.org/content/10.110…
Muscle mito nanotunnels 1/3🧵
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Aleksandra Filipovska retweeted
Mini reunion of team 'Mito Dysfunction' at @CellSymposia #CSMito2024! Wonderful to catch up with Aleks @FilipovskaLab from my PhD days in the Murphy Lab @Mito_Redox @MRC_MBU
Great to catch up with Helena Cochemé and Aleksandra Filipovska in Sitges #CSMito2024 ...both are doing great running their own labs - despite doing their PhDs in my lab...
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Aleksandra Filipovska retweeted
📢Registrations are now open for the ANZSCDB NSW Meeting!
Scan the QR code to secure your ticket 🎟️👇
Scan the QR code to secure your ticket 🎟️👇
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Aleksandra Filipovska retweeted
Better CRISPR base editors!
More efficient nicking of the unedited DNA strand improves the ability to edit hard to reach bases.
@ACSSynBio
pubs.acs.org/doi/10.1021/ac…
More efficient nicking of the unedited DNA strand improves the ability to edit hard to reach bases.
@ACSSynBio
pubs.acs.org/doi/10.1021/ac…
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Aleksandra Filipovska retweeted
Our latest preprint! Some beautiful cell biology in this one.
"Presynapses are mitophagy pit stops that prevent axon degeneration"
biorxiv.org/cgi/content/sh…
Discoveries into the cell biology of of mitophagy in axons, a disease mechanism, and a potential therapeutic avenue.
1/2
"Presynapses are mitophagy pit stops that prevent axon degeneration"
biorxiv.org/cgi/content/sh…
Discoveries into the cell biology of of mitophagy in axons, a disease mechanism, and a potential therapeutic avenue.
1/2
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