Another year and another great Christmas party at @MRC_LMS with @Alexis_Barr and @vaquerizasjm ! ☃️🎄
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Young investigators summer chill on @institutrb with @godi_talk ⛱️🍺
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Further experiments, including targeted methylation sequencing, CRISPR-activation and gene silencing in adipocytes, highlighted regional methylation variations, underlying regulatory elements and novel cellular metabolic effects. #CRISPR 6/8 🧵
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Using Mendelian Randomisation, we inferred the causal effects of methylation on obesity and obesity-induced metabolic disturbances at 59 independent loci. #MendelianRandomisation 5/8 🧵
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We also identified potential interactions between methylation and transcription factors. This could open new avenues in understanding how our genetic code is read and interpreted in the context of obesity. #GeneticResearch 4/8 🧵
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We linked obesity-associated methylation variations to transcriptomic changes in over 500 target genes. #Epigenetics 3/8 🧵
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We conducted an epigenome-wide association study on 190 samples, discovering a whopping 691 loci in subcutaneous and 173 in visceral adipocytes associated with obesity. #Genomics 2/8 🧵
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Freezing morning in London 🥶🥶 barely made it to the @MRC_LMS
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Feeling proud listening @ferencmueller presenting the @daniocode paper on #FEBS Danube #epigenetics Advanced Course!
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And so, #hdbmb2022 organised by @hdbmb_hr concludes with a very inspirational talk from Boris Jokic, which makes us all think how to be better teachers and scientists!
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Congratulations @AnaNov__ on the great talk about the role of RNA exosome on resistance to anti-cancer drug 5-FU presented at #HDBMB2022
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@vjlisnic very nicely explained how our immune system fights cytomegalovirus at #HDBMB2022
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#hdbmb2022 continues with a great talk from @ambriovic on the role of integrin adhesion complexes on actin-microtubule crosstalk
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After excellent #EMBOepigenome it is time for #HDBMB2022 in Brela organised by @hdbmb_hr, which started with the excellent talk from @Kramadan2 !
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#EMBOepigenome kicked off by the talk from one-and-only @OdedRechavi on transgenerational RNA memory! Disclaimer: he didn't want his talk tweeted! 😆
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Thank you @BZunar and @CBM_UPR4301 for providing a state-of-the-art bioavailable copper biosensor!
sciencedirect.com/science/articl…
sciencedirect.com/science/articl…
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