Please welcome the three new PhD candidates in the lab: Ana Martinez-Calvo, Juliette Yunes and Enzo Blaize !
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Quelle tristesse. Un grand monsieur et un ami qui s'en va ! Je me rappellerai longtemps de ta gentillesse, de ton humilité, et des conseils précieux. Toutes mes condoléances à Anne.
[HOMMAGE] Le CNRS a appris avec une grande tristesse le décès de Pierre Joliot, pionnier de la photosynthèse et figure de la recherche au CNRS.
Nos condoléances à sa famille et à ses proches.
👉 insb.cnrs.fr/fr/cnrsinfo/ho…
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Interested to join our team for your PhD ? We are looking for highly motivated PhD fellows ! Please contact us to apply through the France Excellence Eiffel Scholarship programme !
campusfrance.org/en/france-exce…
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Cascales Lab retweeted
If you're interested in doing a postdoc with us on #T6SS #MGE, have a look at this opportunity for the prestigious Azrieli postdoc fellowship

azrielifoundation.org/fellows/intern…
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Cascales Lab retweeted
How do bacteria build their flagella?

We’ve put together an animation of Salmonella flagellum assembly based on cryo-EM and X-ray structures.

From the membrane-embedded machinery to the growing filament, here’s how the parts come together, step-by-step.
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Cascales Lab retweeted
When Pseudomonas is attacked, it strikes back!
Outer membrane damage triggers a tit-for-tat T6SS retaliation via TagQ/TagR protein complex assembly, activating the PpkA kinase.
Congrats to Maxim & team for uncovering this fascinating mechanism!
nature.com/articles/s4146…
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New study in @NAR_Open 🧬
A #T6SS-delivered Rhs toxin from Chromobacterium violaceum, TreThr, is an ADP-ribosyltransferase that selectively modifies charged tRNAThr(GGU), blocking ACC codon decoding & shutting down protein synthesis in rival bacteria.
academic.oup.com/nar/article/54…
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Replying to @CascalesLab
This work complements the study of Jùlia Alves, José da Silva Neto and @SarahCoulthurs1 published earlier this year: jbc.org/article/S0021-…
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New in @CurrentBiology 🦠 Why do bacteria ditch their T6SS weapon? Experimental evolution shows that E. coli keeps it vs susceptible rivals, but loses it when facing immune ones. Great work @bTaillefer_ @JonasDesjardins!

cell.com/current-biolog…
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Very proud to see our review "Anti-type VI tactics: bacterial defenses against T6SS attacks" featured on the Cover of @TrendsBiochem
cell.com/trends/biochem…

Kudos to @NicolasRivard11 for creating this fantastic Cover illustration!
But… do do you recognize the original painting?
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Cascales Lab retweeted
Interested in the Function and Regulation of #T6SS? Do you have relevant experience from your Master's project? Apply to this PhD position in our lab:
biozentrum.unibas.ch/open-positions…
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Happy to share our latest review on the "Structure and function of the #T9SS for protein secretion and cellular motility" to be published in the incoming volume 80 of Annual Review in Microbiology.

Kudos to Yaelle Aouizerate and @doan_thierry !

annualreviews.org/content/journa…
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Cascales Lab retweeted
Our lab is recruiting people at multiple levels: postdoc, graduate student, and RA @IPMBSinica #Taiwan to investigate the evolution and molecular mechanisms of #Agrobacteria #T6SS antibacterial weapon. Check out the job ad and the lab website! Please apply or RT
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Extension of the deadline for latecomers. Register to the Secretion Days in Marseille !

📅 Secretion Days 2026: October 8-9 in Marseille 🌊
🎤Invited speaker : Wilbert Bitter; @wilbertbitter
🆓 Free !
📥 Register here:
docs.google.com/forms/d/e/1FAI…
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Happy to share the last publication of @bTaillefer_, showing that #T6SS heterogeneity is an attenuation strategy to optimizes the trade-off between competitive killing and survival. @PLOSBiology

journals.plos.org/plosbiology/ar…
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Happy to share the last work of Jonas @JonasDesjardins, identifying and characterizing a novel Rhs NAD(P) glycohydrolase delivered by the #T6SS of the major cosmetic contaminant, Pluralibacter gergoviae.

jbc.org/article/S0021-…
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Cascales Lab retweeted
Postdoc opening in my lab @HumboldtUni!

Join our Einstein Foundation-funded collaboration with the Hebrew University of Jerusalem on T3SS, spatial RNA localization, imaging & bacterial cell biology.

📅 Apply by 2 June 2026
🔗 hu.berlin/T3SSjob

#Postdoc #Microbiology
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T2SS ? T4SS ? CDI ? T6SS ? T7SS ?
NO ! The #T9SS is also involved in interbacterial competition !! @CurrentBiology

Great work by Maelle Paillat @maelle_paillat under the supervision of Thierry Doan @doan_thierry

sciencedirect.com/science/articl…
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Cascales Lab retweeted
Glad to share our latest review on the diversity of defense mechanisms against the T6SS!
“Anti-type VI tactics: bacterial defenses against type VI secretion system attacks” is available in Trends in Biochemical Sciences right now.
@CascalesLab
@jpcotelab
authors.elsevier.com/c/1msKv3S6GfYC…
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Very happy that our work on the T6SS ADP-ribosylcyclase toxin made the Cover at JBC
@jbiolchem ! Congratulations Julius @MartinkusJM for designing this Cover !
@DukasJu
@LaurentTerradot
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