Broad Institute retweeted
Th distinct features of colon cancer in the young at single-nucleus resolution, both unfavorable and potentially helpful for understanding why this is on the rise @NatureMedicine
nature.com/articles/s4159…
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Broad Institute retweeted
🔬 New work from the @Schmidt_Center and @ETH_en shows that active adhesome genes and their regulators are spatially clustered in the nucleus, suggesting an association between chromatin organization and gene expression.

🔗 journals.plos.org/plosone/articl…

@broadinstitute
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Broad Institute retweeted
Our atlas of young-onset CRC is finally out in @NatureMedicine! We found a unique biology in younger patients that may explain the aggressive nature of this disease. This was a monumental effort with colleagues at @MassGenBrigham and @broadinstitute. @DFarberYoungCRC
Researchers co-led by @KimmieNgMD of @DanaFarber and @DFarberYoungCRC created the largest single-cell atlas of colorectal cancer ever, identifying age-associated differences that may help research into why #colorectalcancer can be more aggressive in younger adults. qO
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Broad Institute retweeted
New paper in @NatureMedicine with @KimmieNgMD and @AnaAndersonlab! Early-onset colorectal cancer (#EOCRC) is rising. Our single-nucleus atlas of 189 tumors reveals age-associated differences and offers a resource for further research.
nature.com/articles/s4159…
More people younger than 50 are being diagnosed with colorectal cancer, and the disease is often more aggressive. A single-cell study of colorectal tumors reveals differences in cell composition and expression in tumors from younger patients. broad.io/single-cell-co…
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Broad Institute retweeted
Researchers co-led by @KimmieNgMD of @DanaFarber and @DFarberYoungCRC created the largest single-cell atlas of colorectal cancer ever, identifying age-associated differences that may help research into why #colorectalcancer can be more aggressive in younger adults. qO
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More people younger than 50 are being diagnosed with colorectal cancer, and the disease is often more aggressive. A single-cell study of colorectal tumors reveals differences in cell composition and expression in tumors from younger patients. broad.io/single-cell-co…
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Broad Institute retweeted
The 2027 HCA General Meeting will take place in The Hague, the Netherlands, on 29 June - 1 July. Early bird registration for the #HCA2027GM is now open and runs until 28 February 2027.
For more information and to register see buff.ly/YvwAilr
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Broad scientists discover that mechanism underlying Huntington’s disease in striatum is also present in the neocortex, suggesting that new drugs under development could potentially protect multiple parts of the brain. broad.io/HDneocortex
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Broad Institute retweeted
Join the @Schmidt_Center on Tuesday, November 3 at 4:00 pm (🍪 at 3:30 pm) for our colloquium with @eliasbareinboim, Associate Professor, Dept. of Computer Science and Director, CausalAI Lab at
@Columbia.

Learn more and register: ericandwendyschmidtcenter.org/events/elias-b…

@broadinstitute
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Now accepting nominations for the 2027 Merkin Prize — a $400,000 international award recognizing advances that improved human health through diagnosis, treatment or prevention of disease. ➡️ Submit by Dec 4, 2026: merkinprize.org
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Broad Institute retweeted
Our latest analysis of microbiome-reactive T cells, which revealed a unique, pro-inflammatory TMIGD2-hi subset of Th17 cells that expands in IBD and enriches spatially at the epithelium, is now online @ImmunityCP!

sciencedirect.com/science/articl…
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Broad Institute retweeted
1/7 🌾🐄  Our letter is out in @science: AI biosecurity must include agriculture.

Recently biological AI has brought biosecurity to the center of public debate, but most attention is on human pathogens. Crops and livestock are a major blind spot. 🧵

Gift link: science.org/eprint/6ARDVAU…

@broadinstitute @sabeti_lab @JonxFeldman @talxfeldman
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A cancer detection technology developed at Broad now powers a next-generation MRD test launched by Abbott. The Oncodetect® test is designed to find traces of cancer DNA in patients who have undergone treatment, and is the result of years of collaboration. broad.io/MAESTRO-news
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Broad Institute retweeted
To mark our tenth Anniversary month, watch HCA Co-Founder Aviv Regev reveal her hopes for the Human Cell Atlas initiative, and how it is already helping to improve medicine.
#HumanCellAtlas #Healthcare
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Broad Institute retweeted
The integrated HCA v1 Human Gut Cell Atlas is now available on the HCA Data Portal! Integrating nearly 1 million single cells from 265 donors, the #Gut Atlas is a reference map to understand gut health and diseases like Crohn’s.

Explore here buff.ly/X0Rfj39
#Genomics
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Join us on Thurs. October 29, from 6-8 pm for Discovery After Dark! Experience science firsthand through interactive activities, take on the challenge of an Operation Outbreak simulation, and meet Broad scientists! Advanced registration required. Register: broad.io/DaD
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Broad Institute retweeted
Applications are open for the Klarman Fellowship at @broadinstitute! We are looking for postdoctoral researchers to join the GaMBiT Initiative to develop innovative technologies that translate human genetic discoveries into disease mechanisms, biomarkers, and therapeutic leads.
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Broad Institute retweeted
As we celebrate a decade of collaboration, HCA Co-Founder Sarah Teichmann shares why she and Aviv Regev joined forces to bring this international scientific consortium together. Hear Sarah tell the story.
@teichlab #HumanCellAtlas
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Five Broad Institute members were elected to the National Academy of Medicine this year: @AnnaGreka, Kim Stegmaier, Kathleen Burns, @jorsmo, and @mbyaffe.

We’re thrilled to have so many NAM members engaged in our community. Congrats, all!
Congratulations and welcome to the 100 new members elected today to the National Academy of Medicine's class of 2026!

Read the full announcement: nam.edu/classof2026

#NAMmtg #NAMedicine
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Join us on October 29, from 6-8 pm for Discovery After Dark! Explore interactive exhibits, participate in hands-on activities, put your outbreak response skills to the test, and interact with Broad scientists! Advanced registration required. Register at: broad.io/DaD
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