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More takes. Less waiting. More room for the idea you almost didn’t try.
mischief 1 is here. Go make something.
mischief 1 is here. Go make something.
today, we introduce a little mischief to the world.
for four years, we’ve been brewing real brain cells on electrodes to understand how they compute. now, we’ve turned those discoveries into a video model anyone can use.
from 0.5¢ a second, mischief 1 is at least 5x faster than st image-to-video model on @fal and @OpenRouter. soon to be on @awscloud marketplace.
it’s not a delusion anymore. biocompute is real, commercial and this is just the beginning.
happy halloween.
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A little imagination and a whole lot of mischief at @TechCrunch Founder Summit.
Watching people bring their ideas to life in the palms of their hands. 5-second videos generated in just 5.8 seconds on average.
The reaction? “Wait, how are you doing this?”
Watching people bring their ideas to life in the palms of their hands. 5-second videos generated in just 5.8 seconds on average.
The reaction? “Wait, how are you doing this?”
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Wait, what?
We grow living neurons on electrode arrays, encode information with patterned electrical stimulation and record how the network processes it over time. We study things like recurrent dynamics and how activity settles into stable patterns. We then translate those observations into algorithms that make AI more efficient and runs on GPUs.
We grow living neurons on electrode arrays, encode information with patterned electrical stimulation and record how the network processes it over time. We study things like recurrent dynamics and how activity settles into stable patterns. We then translate those observations into algorithms that make AI more efficient and runs on GPUs.
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What happens when you take the cost and time constraints out of creativity? @JustinHackney33 gives us a glimpse of what's possible.
2,511 clips. five seconds each. 720 p.
$125.55 total.
that’s what @JustinHackney33 of @WonderStudiosX, who made our launch film, generated with mischief 1. generating that much video with wan 2.2 would cost about $1,017.
the point isn’t just cheaper video. it’s the freedom to rationing every take.
@JustinHackney33 came to our lab to see where it starts.
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The Biological Computing Co. (TBC) retweeted
A little mischief for Halloween 🎃
mischief 1 from The Biological Computing Co. turns an image into video, using four years of research on real brain cells grown on electrodes.
From $0.005 a second, live now on OpenRouter.
openrouter.ai/tbc/mischief-1
mischief 1 from The Biological Computing Co. turns an image into video, using four years of research on real brain cells grown on electrodes.
From $0.005 a second, live now on OpenRouter.
openrouter.ai/tbc/mischief-1
TBC mischief 1 is now live on OpenRouter 🧠🎬
Image-to-video from The Biological Computing Company: give it a starting image and a prompt, get back a 3s or 5s clip at 480p or 720p.
From $0.005 per second of video.
openrouter.ai/tbc/mischief-1
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mischief 1 is out in the world.
Tonight, we celebrate the people who made it happen.
Happy Mischief Night!
Tonight, we celebrate the people who made it happen.
Happy Mischief Night!
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The Biological Computing Co. (TBC) retweeted
This is honestly one of the most fascinating developments in AI I've seen in a while.
A startup called The Biological Computing Co. just launched Mischief 1, an AI video generation model developed using research from actual living human brain cells. The company says its technology makes video generation 5 times faster while reducing costs by roughly 80%. For the past four years, they've been growing living neurons in laboratories and connecting them to thousands of electrodes to study how the human brain processes information. Think about it because our brains can process enormous amounts of information while consuming relatively little energy, whereas AI models require massive amounts of computing power and electricity.
What makes this interesting is that they're taking what they learn from these living neurons and translating those discoveries into software that makes existing AI models significantly more efficient. The brain cells aren't directly generating the videos but rather helping researchers discover entirely new ways to optimize AI. And the economics are incredible. Mischief 1 starts at just half a cent per second of generated video. It's already being made commercially available through fal and OpenRouter, with plans to expand onto AWS Marketplace.
But I think the opportunity here goes WAY beyond video generation. Imagine applying this technology to large language models, robotics, autonomous vehicles, and other AI applications. If companies can get significantly more performance from the same computing infrastructure, it could completely change the economics of artificial intelligence. Think about how much Microsoft, Google, Meta, and Amazon are spending on AI infrastructure. Even modest improvements in computational efficiency could translate into billions of dollars in savings at their scale, while allowing them to build even more powerful AI systems. And this could be just as exciting for companies like NVIDIA and AMD. As AI becomes cheaper and more efficient to run, it becomes practical to deploy in more products, industries, and applications, potentially driving even greater demand for computing power.
I think the biggest takeaway is that the next major breakthrough in AI might not come from building bigger models or adding more GPUs but rather from understanding how the human brain computes and applying those discoveries to artificial intelligence. We're literally using living brain cells to help make AI better, and this could be just the beginning of an entirely new approach to computing.
A startup called The Biological Computing Co. just launched Mischief 1, an AI video generation model developed using research from actual living human brain cells. The company says its technology makes video generation 5 times faster while reducing costs by roughly 80%. For the past four years, they've been growing living neurons in laboratories and connecting them to thousands of electrodes to study how the human brain processes information. Think about it because our brains can process enormous amounts of information while consuming relatively little energy, whereas AI models require massive amounts of computing power and electricity.
What makes this interesting is that they're taking what they learn from these living neurons and translating those discoveries into software that makes existing AI models significantly more efficient. The brain cells aren't directly generating the videos but rather helping researchers discover entirely new ways to optimize AI. And the economics are incredible. Mischief 1 starts at just half a cent per second of generated video. It's already being made commercially available through fal and OpenRouter, with plans to expand onto AWS Marketplace.
But I think the opportunity here goes WAY beyond video generation. Imagine applying this technology to large language models, robotics, autonomous vehicles, and other AI applications. If companies can get significantly more performance from the same computing infrastructure, it could completely change the economics of artificial intelligence. Think about how much Microsoft, Google, Meta, and Amazon are spending on AI infrastructure. Even modest improvements in computational efficiency could translate into billions of dollars in savings at their scale, while allowing them to build even more powerful AI systems. And this could be just as exciting for companies like NVIDIA and AMD. As AI becomes cheaper and more efficient to run, it becomes practical to deploy in more products, industries, and applications, potentially driving even greater demand for computing power.
I think the biggest takeaway is that the next major breakthrough in AI might not come from building bigger models or adding more GPUs but rather from understanding how the human brain computes and applying those discoveries to artificial intelligence. We're literally using living brain cells to help make AI better, and this could be just the beginning of an entirely new approach to computing.
today, we introduce a little mischief to the world.
for four years, we’ve been brewing real brain cells on electrodes to understand how they compute. now, we’ve turned those discoveries into a video model anyone can use.
from 0.5¢ a second, mischief 1 is at least 5x faster than st image-to-video model on @fal and @OpenRouter. soon to be on @awscloud marketplace.
it’s not a delusion anymore. biocompute is real, commercial and this is just the beginning.
happy halloween.
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Incredible work @MengTo. This is a video worth watching.
I got the chance to work on the landing page for a new video model from a lab that grows real brain cells.
insanely cheap at half a cent a second.
had a lot of fun creating three.js concepts with opus 5.5. here's my workflow.
check out mischief-1: app.tbc.co
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Can living brain cells make AI faster? 🧠
@BioComputingCo co-founders @AlexKsendzovsky and Jon Pomeraniec explain how studying lab-grown neurons is helping them develop faster, cheaper AI video generation, with potential applications in robotics and beyond.
📺 YouTube: link.theneurondaily.com/r/tnREGK
🎧 Spotify: link.theneurondaily.com/r/4TH63r
🎙️ Apple Podcast: link.theneurondaily.com/r/BvN0LB
#BiologicalComputing #AIResearch #Neuroscience #GenerativeAI #TheNeuron
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check it here: youtube.com/watch?v=8c6KLM…
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Our big bet: the next great compute multiplier will come from biology.
Instead of just adding more chips and power, we study how living neurons compute and turn those discoveries into faster, more efficient AI on today's hardware.
More from the compute we already have.
Instead of just adding more chips and power, we study how living neurons compute and turn those discoveries into faster, more efficient AI on today's hardware.
More from the compute we already have.
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It’s about @TIME.
TBC has been named one of TIME's Best Inventions of 2026.
Real neurons. A new way to compute. And we're just getting started.
time.com/collection/bes…
#TIMEBestInventions
TBC has been named one of TIME's Best Inventions of 2026.
Real neurons. A new way to compute. And we're just getting started.
time.com/collection/bes…
#TIMEBestInventions
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Neurotech is having a moment, and SF is right at the center of it.
Big shoutout to @naveen101 for bringing the community together at #SFTechWeek!
Meanwhile, @AlexKsendzovsky holding court on the future of biological computing.
Big shoutout to @naveen101 for bringing the community together at #SFTechWeek!
Meanwhile, @AlexKsendzovsky holding court on the future of biological computing.
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Biological computing needs scientists and builders.
Former Meta and NBCUniversal CIO Atish Banerjea is joining TBC as an Advisor to help build the path to real-time biological compute.
Welcome to TBC, Atish.
Read the full announcement → tbc.co/post/atish-ban…
Former Meta and NBCUniversal CIO Atish Banerjea is joining TBC as an Advisor to help build the path to real-time biological compute.
Welcome to TBC, Atish.
Read the full announcement → tbc.co/post/atish-ban…
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The Biological Computing Co. (TBC) retweeted
I just tried @BioComputingCo neuron post trained video models 75% cost reduction and 10x faster with better quality is damn impressive!
app.tbc.co to try for yourself.
My results: app.tbc.co/compare/job_c0…
app.tbc.co to try for yourself.
My results: app.tbc.co/compare/job_c0…
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