Amanda Wiggenhorn retweeted
Hello world! We are FAST (Future Advancers in Science & Technology). We build programs where scientist mentors work with students from under-resourced high schools on research projects based on students’ own passions & curiosities - inventing or discovering something new! (1/4)
1
2
1
75
Amanda Wiggenhorn retweeted
My lab is recruiting a postdoc fellow to characterize new biochemical pathways that control taurine and glucose metabolism. Email me at wei.wei2@wisc.edu to apply! Please help RT🙏 @longlabstanford @JudithSimcox @UWBiochem
6
122
292
38,558
Amanda Wiggenhorn retweeted
Sharing our latest review on peptide hormones by Laetitia Coassolo @Laeti67202 and Amanda Wiggenhorn @AmandaWigg_ in Trends in Biochemical Sciences
@TrendsBiochem @StanfordPath
Free full text: sciencedirect.com/science/articl…
@TrendsBiochem @StanfordPath
Free full text: sciencedirect.com/science/articl…
2
11
45
3,082
So excited for you and your future work! Congrats!!
I'm beyond thrilled to announce that I will be joining the Biochemistry Department at the University of Wisconsin–Madison this fall as an Assistant Professor. My lab will focus on deorphanizing biochemical pathways that regulate nutrient metabolism @UWBiochem @uwmadisonipib
0
0
1
164
Amanda Wiggenhorn retweeted
Today in @Nature, we share our latest paper. We developed an algorithm to predict novel peptides cleaved by proconvertases across all human tissues. Using this method, we identified BRP, a brain-derived anti-obesity peptide.
nature.com/articles/s4158…
nature.com/articles/s4158…
23
137
588
70,798
Amazing work lead by Laetitia! Congrats! Super cool story highlighting a new signaling peptide!
Thrilled to share that my work is out in @Nature. Here, we introduce Peptide Predictor, a tool for identifying new bioactive peptides. Using this method, we discovered BRP, an anti-obesity peptide. Huge thanks to the @SvenssonLab and all our collaborators! nature.com/articles/s4158…
0
0
5
466
Amanda Wiggenhorn retweeted
Our new paper in Cell Systems demonstrates how AlphaFold can predict the binding between ligands and cell surface receptors. Congrats @nbds_bio and co-authors from K.C. Garcia lab
See paper here: cell.com/cell-systems/a…
@StanfordPath @StanfordDRC
See paper here: cell.com/cell-systems/a…
@StanfordPath @StanfordDRC
5
12
73
5,156
Amanda Wiggenhorn retweeted
Really excited to share our recent discovery of a novel pathway of B-hydroxybutyrate metabolism linked to energy balance! Thanks to @longlabstanford and all collaborators! biorxiv.org/content/10.110…
2
12
64
12,908
Amanda Wiggenhorn retweeted
From @mariadolores_mg, we dive into the biochemistry and physiology of ketosis- and show that the metabolic pathways of BHB extend beyond primary metabolism to include bioactive secondary ketone metabolites @WuTsaiAlliance @Stanford_ChEMH @StanfordPath
Really excited to share our recent discovery of a novel pathway of B-hydroxybutyrate metabolism linked to energy balance! Thanks to @longlabstanford and all collaborators! biorxiv.org/content/10.110…
0
10
50
6,776
Amanda Wiggenhorn retweeted
Today in @NatureComms we describe the role of SLC17A1/3 in urine Lac-Phe efflux. The surprisingly insight that unlocked this pathway? Lac-Phe mis-assignment to “1-carboxyethyl phenylalanine” @Metabolon. Congratulations @veronical1411 @Stanford_ChEMH
nature.com/articles/s4146…
nature.com/articles/s4146…
1
12
76
6,901
Amanda Wiggenhorn retweeted
I'm excited to share our latest collaboration with @fidocklab using mixed alkyl/aryl phosphonates to identify possible drug targets in Plasmodium. Our work offers a possible method for deciphering important drug targets, mechanism of action, and mechanisms of resistance.
1
1
12
791
Amanda Wiggenhorn retweeted
Our paper using mixed alkyl aryl phosphonates to identify serine hydrolases in Plasmodium falciparum that are potential drug targets is out. Great work from @ChemBio_John and collaborations with @fidocklab. Free Download here -authors.elsevier.com/a/1jarB8jWWJxM…
cell.com/cell-chemical-…
cell.com/cell-chemical-…
0
12
43
3,685
Amanda Wiggenhorn retweeted
Today in @Nature, we discover a new enzyme in mammalian taurine metabolism- and uncover a chemical connection between diet, genetics, and body weight. Congrats @WeiWei_Stanford @Stanford_ChEMH @StanfordPath @mfgrp @cholsoon_jang @SvenssonLab @Lingyin_Lab
nature.com/articles/s4158…
nature.com/articles/s4158…
27
77
332
49,115
Amanda Wiggenhorn retweeted
Thrilled to share our MultiMap paper is now published online on Science. @ScienceMagazine With @realJimWells, we present a multiscale photocatalytic proximity labeling platform for interactome profiling. science.org/doi/10.1126/sc…
21
35
195
48,494
Amanda Wiggenhorn retweeted
Congratulations to @AmandaWigg_ and @veronical1411, the newest 2024 PhD graduates of @StanfordUChem @StanfordMed @Stanford_ChEMH We are all very proud of both of you. Congratulations and job well done 🎉🎉
0
5
73
4,425
Amanda Wiggenhorn retweeted
Congratulations to our very own Dr @AmandaWigg_ on a successful thesis defense!!! Great talk and well done @Stanford_ChEMH @StanfordUChem @StanfordPath
2
4
44
3,536
Amanda Wiggenhorn retweeted
Excited to be at @BrainResilience symposium today!! Check out @skxiao_nju poster number 42, about metformin, exercise, and gut brain crosstalk @Stanford_ChEMH @StanfordBrain
0
3
22
5,224
Amanda Wiggenhorn retweeted
Here we show that prior to 2022, the metabolite Lac-Phe was mis-annotated in @Metabolon datasets as “1-carboxyethylphenylalanine.” We use this information to identify physiologic urine Lac-Phe transporters. Incredible detective work by @veronical1411 biorxiv.org/content/10.110…
5
20
80
10,087
Amanda Wiggenhorn retweeted
Fearless and prolific, @WeiWei_Stanford is at it again- this time connecting an enigmatic branch of taurine metabolism to body weight control. Congratulations to all, and extra thx to our dear collaborators @mfgrp @SvenssonLab @cholsoon_jang @Stanford_ChEMH @StanfordPath
Very excited to share our recent discovery of a novel taurine metabolism pathway! We identified the orphan enzyme PTER as the predominant taurine N-acetyltransferase/hydrolase that regulates energy balance @longlabstanford
biorxiv.org/content/10.110…
3
4
46
6,568
Amanda Wiggenhorn retweeted
Very excited to share our recent discovery of a novel taurine metabolism pathway! We identified the orphan enzyme PTER as the predominant taurine N-acetyltransferase/hydrolase that regulates energy balance @longlabstanford
biorxiv.org/content/10.110…
biorxiv.org/content/10.110…
10
17
115
39,471