For patients undergoing surgery to correct complex skull and facial abnormalities, external devices used to gradually reposition bones can increase the risk of infection, mechanical complications, and psychological distress.

Researchers sought to overcome these challenges by rnal, magnetically actuated craniofacial distraction system, using finite element modeling to optimize its magnetic coupling mechanism. They compared a conventional magnetic configuration with a redesigned U-shaped architecture incorporated into the new system, revealing several key findings:

🔹 Conventional magnetic coupling weakened substantially as separation distance increased.
🔹 The redesigned system achieved up to six times greater peak torque and more than five times greater torsional stiffness.
🔹 Improved magnetic coupling maintained clinically relevant torque transmission across greater distances.

Demonstrating the feasibility of magnetic actuation through soft tissue represents a step toward fully implantable craniofacial devices that could reduce treatment-related complications and patient burden, pending further preclinical validation.

𝗥𝗲𝗮𝗱 𝗺𝗼𝗿𝗲: link.springer.com/article/10.100…

𝗦𝘁𝘂𝗱𝘆: The Magnet-Actuated Craniofacial (MAC) Distraction System: Magnetic Coupling Modeling

𝗔𝘂𝘁𝗵𝗼𝗿𝘀: Mohammed A. Fouda, David Dostal, and Caitlin E. Hoffman

@WeillCornell
@WCMCBrainSpine
@nyphospital

𝗦𝘂𝗯𝗺𝗶𝘁 𝘆𝗼𝘂𝗿 𝗺𝗮𝗻𝘂𝘀𝗰𝗿𝗶𝗽𝘁: link.springer.com/journal/10439

Stroke survivors may experience impaired blood flow to the brain long after the initial injury, yet few drug-free interventions are available to improve circulation during rehabilitation.

Researchers addressed this need by evaluating whether low-frequency electrical stimulation leg could increase oxygen delivery to brain tissue. In 18 ischemic stroke survivors, they used a wearable device to administer stimulation across three body positions and employed cardiovascular computational modeling to examine the underlying physiological mechanisms. Stimulation produced greater increases in cortical oxygenation at higher intensities, particularly in upright positions and participants with larger strokes, while computational modeling indicated that increased venous return and cardiac output contributed to these effects.

Although larger controlled trials are needed, these findings could inform the development of wearable therapies tailored to patients' cardiovascular responses and rehabilitation needs, potentially expanding treatment options during stroke recovery.

𝗥𝗲𝗮𝗱 𝗺𝗼𝗿𝗲: link.springer.com/article/10.100…

𝗦𝘁𝘂𝗱𝘆: Enhancement of Cerebral Oxygenation by Lower-Limb Neuromuscular Electrical Stimulation in Stroke Survivors

𝗔𝘂𝘁𝗵𝗼𝗿𝘀: Anirban Dutta, Yashika Arora, Sandra Leason, @AllamHarfoush, and Kausik Chatterjee

@unibirmingham
@unibirm_CMH
@aiims_newdelhi
@TheCountessNHS
@NIRSlearn

𝗦𝘂𝗯𝗺𝗶𝘁 𝘆𝗼𝘂𝗿 𝗺𝗮𝗻𝘂𝘀𝗰𝗿𝗶𝗽𝘁: link.springer.com/journal/10439

The Annals of Biomedical Engineering (ABME) is pleased to announce the recipients of its 𝟮𝟬𝟮𝟲 𝗕𝗲𝘀𝘁 𝗣𝗮𝗽𝗲𝗿 𝗔𝘄𝗮𝗿𝗱 – 𝗢𝗿𝗶𝗴𝗶𝗻𝗮𝗹 𝗥𝗲𝘀𝗲𝗮𝗿𝗰𝗵: Young-Jun Koo, Naomichi Ogihara, and Seungbum Koo for their paper, “Active Arm Swing During Running Improves the Upper Body and Metabolic Energy Efficiency.”

This study investigates how arm swing contributes to stability and energy efficiency during running. Using full-body musculoskeletal simulations incorporating 150 muscles, the researchers compared active arm swing, passive arm swing, and fixed arms. Despite requiring more energy from the upper limb muscles, active arm swing reduced torso rotation and overall metabolic energy consumption in the simulations – findings that could inform strategies for improving athletic performance and supporting rehabilitation.

ABME congratulates the authors and commends their contribution to the field of biomechanics. Their work exemplifies the journal’s mission to publish innovative research that advances biomedical engineering and improves human health.

𝗥𝗲𝗮𝗱 𝗺𝗼𝗿𝗲: link.springer.com/article/10.100…

@ETRINewsmaker
@UTokyo_News_en
@UTokyo_News
@kaistpr

𝗦𝘂𝗯𝗺𝗶𝘁 𝘆𝗼𝘂𝗿 𝗺𝗮𝗻𝘂𝘀𝗰𝗿𝗶𝗽𝘁: link.springer.com/journal/10439

Animal testing remains central to biomedical research despite its limitations in predicting human responses, while promising alternatives have yet to achieve the consistency needed for widespread adoption.

A letter to the editor discusses a major initiative to improve the ternatives – the National Institutes of Health’s $87 million investment in a Standardized Organoid Modeling Center, established to advance the standardization and validation of human-derived organoids, 3D cell structures that reproduce key features of human organs.

The authors highlight how consistent production methods, artificial intelligence, and rigorous validation could improve the reproducibility and reliability of these models across laboratories. They also emphasize the importance of balancing standardization with experimental flexibility and recognizing the limitations of organoids in replicating complex interactions between organ systems.

The initiative could help establish a more rigorous framework for determining when organoids are appropriate for specific research questions, strengthening the scientific basis for their use in disease modeling and drug development.

𝗥𝗲𝗮𝗱 𝗺𝗼𝗿𝗲: link.springer.com/article/10.100…

𝗟𝗲𝘁𝘁𝗲𝗿: NIH’s Standardized Organoid Modeling Center: A Critical Step Toward Reproducible NAMs and Reduced Animal Testing

𝗜𝗺𝗮𝗴𝗲: Brain organoid depicting neural stem cells in green and neurons in magenta. Both cell types are abundant, showing normal development. 𝘊𝘳𝘦𝘥𝘪𝘵: 𝘕𝘢𝘵𝘪𝘰𝘯𝘢𝘭 𝘐𝘯𝘴𝘵𝘪𝘵𝘶𝘵𝘦 𝘰𝘧 𝘈𝘭𝘭𝘦𝘳𝘨𝘺 𝘢𝘯𝘥 𝘐𝘯𝘧𝘦𝘤𝘵𝘪𝘰𝘶𝘴 𝘋𝘪𝘴𝘦𝘢𝘴𝘦𝘴

𝗔𝘂𝘁𝗵𝗼𝗿𝘀: Liangbin Zhou and Yiting Lei

@CUHKofficial

𝗦𝘂𝗯𝗺𝗶𝘁 𝘆𝗼𝘂𝗿 𝗺𝗮𝗻𝘂𝘀𝗰𝗿𝗶𝗽𝘁: link.springer.com/journal/10439

The formation of new blood vessels is essential for healing and development – a delicate process in which changes in surrounding tissues can alter chemical signals and may contribute to vascular abnormalities.

Researchers developed a computational method to examine how the sues affects the distribution of vascular endothelial growth factor (VEGF), a signaling protein that helps regulate blood vessel formation. Using time-lapse images of developing vascular networks, they simulated VEGF transport as tissues expanded and vessel networks changed shape. Their findings showed that tissue growth substantially altered the distribution of VEGF, potentially influencing where and in which direction new vessels form.

Clarifying how the physical environment shapes the signals governing new blood vessel formation could inform more targeted interventions for vascular disorders, helping clinicians identify when and where treatment may be most effective.

𝗥𝗲𝗮𝗱 𝗺𝗼𝗿𝗲: link.springer.com/article/10.100…

𝗦𝘁𝘂𝗱𝘆: Computational Modeling Unveils the Impact of Tissue Growth and Vascular Remodeling on the Distribution of Interstitial Chemical Species

𝗔𝘂𝘁𝗵𝗼𝗿𝘀: Adithya Srinivasan, Mario de Lucio, Siavash Ghaffari, Elizabeth A. V. Jones, and @hectorgomez1980

@LifeAtPurdue
@PurdueME
@PurdueBME
@KU_Leuven
@JonesLab_KUL

𝗦𝘂𝗯𝗺𝗶𝘁 𝘆𝗼𝘂𝗿 𝗺𝗮𝗻𝘂𝘀𝗰𝗿𝗶𝗽𝘁: link.springer.com/journal/10439

The aortic valve opens and closes with every heartbeat, but accurately measuring how its tissue stretches and changes shape remains a challenge, particularly in patients with abnormal valve anatomy.

Researchers sought to overcome these limitations by combining finite element mage registration to improve patient-specific tracking of aortic valve deformation using 4D echocardiography and CT. Testing in 20 patients revealed several key findings:

🔹 Leaflet tracking accuracy improved by 40% over direct image registration.
🔹 Tissue strain estimates accounted for some uncertainty in the finite element model.
🔹 Preliminary findings suggested that strain differences between adult trileaflet and pediatric valves may primarily reflect changes in tissue area rather than shape distortion.

Refined characterization of individual valve mechanics could eventually help clinicians evaluate surgical repair and replacement options, with the potential to support more targeted treatment planning.

𝗥𝗲𝗮𝗱 𝗺𝗼𝗿𝗲: link.springer.com/article/10.100…

𝗦𝘁𝘂𝗱𝘆: Biomechanically Informed Image Registration for Patient-Specific Aortic Valve Strain Analysis

𝗔𝘂𝘁𝗵𝗼𝗿𝘀: Mohsen Nakhaei, @PouchAlison, Silvani Amin, Matthew Daemer, Christian Herz, Natalie Yushkevich, Lourdes Al Ghofaily, Nimesh Desai, Joseph Bavaria, Matthew A. Jolley, and @wensi_wu

@CHOP_Research
@HeartCare4Kids
@PennMedicine
@pennbioeng
@MEAM_Penn
@TJUHospital
@JolleyLab

𝗦𝘂𝗯𝗺𝗶𝘁 𝘆𝗼𝘂𝗿 𝗺𝗮𝗻𝘂𝘀𝗰𝗿𝗶𝗽𝘁: link.springer.com/journal/10439

For patients undergoing spinal fusion, recovery depends in part on implants that hold the spine steady while helping surrounding bone grow and remain strong.

With these healing demands in mind, researchers performed a scoping review of scientific literature and issued patents to materials and geometries of lumbar and cervical interbody devices. The authors highlight porous titanium produced by 3D printing and titanium coated with PEEK as promising options for balancing mechanical stability with bone integration. They also describe intricate curved and spiral structures designed to distribute forces more evenly and encourage bone growth.

A better understanding of how implant materials and geometry work together could guide designs that provide lasting spinal stability while reducing the risk of implant failure and preserving the health of surrounding bone.

𝗥𝗲𝗮𝗱 𝗺𝗼𝗿𝗲: link.springer.com/article/10.100…

𝗥𝗲𝘃𝗶𝗲𝘄: Material and Geometric Innovations in Lumbar and Cervical Interbody Devices: A Systematic Scoping Review

𝗔𝘂𝘁𝗵𝗼𝗿𝘀: Elliot Alonso Alcántara-Arreola and Christopher René Torres-SanMiguel

@IPN_MX

𝗦𝘂𝗯𝗺𝗶𝘁 𝘆𝗼𝘂𝗿 𝗺𝗮𝗻𝘂𝘀𝗰𝗿𝗶𝗽𝘁: link.springer.com/journal/10439

Conventional artificial lenses implanted in the eye cannot always correct complex vision problems, particularly in patients with irregularities in the cornea.

Assessing a potential alternative, researchers conducted a systematic review of small-aperture intraocular implants, light to reduce the effects of optical irregularities. The authors analyzed clinical and preclinical evidence indicating that these implants can extend the range of distances at which objects appear in focus and reduce dependence on glasses, even in eyes with complex abnormalities. However, reduced light transmission may impair vision in dim conditions, and the implants can make examination of the retina more difficult.

These insights into the benefits and limitations of small-aperture optics could help clinicians identify suitable patients and refine surgical approaches when conventional lenses fall short.

𝗥𝗲𝗮𝗱 𝗺𝗼𝗿𝗲: link.springer.com/article/10.100…

𝗥𝗲𝘃𝗶𝗲𝘄: Therapeutic Value and Optical Performance of Small-Aperture Intraocular Implants: A Systematic Review

𝗔𝘂𝘁𝗵𝗼𝗿𝘀: Juan J. Prados-Carmona, Mayelín Pérez-Perdomo, Alberto Villarrubia-Cuadrado, Miguel González-Andrades, Álvaro Sánchez-Ventosa, Marta Villalba-González, Timoteo González-Cruces, Yolanda Jiménez-Gómez, and Antonio Cano-Ortiz

@IMIBIC
@HUReinaSofia
@HArruzafa
@Roche
@LoyolaAnd
@UEuropea

𝗦𝘂𝗯𝗺𝗶𝘁 𝘆𝗼𝘂𝗿 𝗺𝗮𝗻𝘂𝘀𝗰𝗿𝗶𝗽𝘁: link.springer.com/journal/10439

Foot pain and walking disorders can be difficult to treat in part because clinicians still lack a precise grasp of how the foot’s intricate structure manages load with every step.

To better understand this mechanical complexity, researchers developed a 3D finite element model of of forward dynamic simulation during the stance phase of walking.

Unlike simplified musculoskeletal models, this anatomically detailed representation incorporated bones, soft tissues, ligaments, and the plantar aponeurosis, and was driven by experimentally measured tibial motion and estimated muscle forces. The simulations closely matched experimental ground reaction forces, plantar pressure patterns, and bone kinematics, while also enabling estimation of internal stresses and strains that cannot be measured directly in vivo.

By illuminating how internal foot structures bear and distribute forces, this framework could support improved orthotic design, surgical planning, and prevention strategies that reduce pain and preserve mobility over the long term.

𝗥𝗲𝗮𝗱 𝗺𝗼𝗿𝗲: link.springer.com/article/10.100…

𝗦𝘁𝘂𝗱𝘆: Simulating Human Foot Mechanics During Walking Based on an Anatomically Detailed Forward Dynamic Finite Element Model

𝗔𝘂𝘁𝗵𝗼𝗿𝘀: Kohta Ito, Yuka Matsumoto, Hiroyuki Seki, Takeo Nagura, and Naomichi Ogihara

𝗦𝘂𝗯𝗺𝗶𝘁 𝘆𝗼𝘂𝗿 𝗺𝗮𝗻𝘂𝘀𝗰𝗿𝗶𝗽𝘁: link.springer.com/journal/10439

Although a child's ability to maintain balance develops throughout childhood, the extent to which foot structure influences this process remains unclear.

Engineers examined the association between foot morphology and postural sway in 178 children aged 6–11 using a form. Girls aged 8–9 with high arches exhibited greater sway than those with normal arches, with a similar trend observed among older girls. In contrast, boys aged 10–11 with flat feet demonstrated reduced sway under certain testing conditions, suggesting that the relationship between foot morphology and postural stability varies by age and sex.

Variations in how foot structure affects balance could inform more targeted pediatric assessments, helping clinicians identify children who may benefit from closer monitoring or balance training to support healthy motor development and reduce the risk of future lower-limb dysfunction.

𝗥𝗲𝗮𝗱 𝗺𝗼𝗿𝗲: link.springer.com/article/10.100…

𝗦𝘁𝘂𝗱𝘆: Influence of Foot Morphology on Postural Sway During Childhood

𝗔𝘂𝘁𝗵𝗼𝗿𝘀: Federico Arippa, Bruno Leban, Micaela Porta, Giulia Casu, and Massimiliano Pau

@univca

𝗦𝘂𝗯𝗺𝗶𝘁 𝘆𝗼𝘂𝗿 𝗺𝗮𝗻𝘂𝘀𝗰𝗿𝗶𝗽𝘁: link.springer.com/journal/10439

Even after a surgical wound has been stitched closed, the tension holding its edges together can change over time, potentially compromising the stability of the repair.

Researchers investigated these mechanical changes by developing a measurement system that simultaneously applied forces, and closure strength using silicone specimens with simulated incisions. The sutured configuration produced approximately 20% greater tension relaxation than equivalent uniaxial loading, while wound closure strength initially decreased by 5–10% before partially recovering. Increasing initial suture tension from 0.3 to 0.5 N improved closure strength by less than 5%, suggesting limited benefits from tighter suturing.

Quantifying how mechanical loads change over time could help surgeons identify the optimal timing for postoperative adjustments, with the longer-term goal of maintaining wound stability throughout recovery.

𝗥𝗲𝗮𝗱 𝗺𝗼𝗿𝗲: link.springer.com/article/10.100…

𝗦𝘁𝘂𝗱𝘆: A Multimodal Measurement System for Quantifying Time-Dependent Suture Tension Relaxation and Wound Closure Strength

𝗔𝘂𝘁𝗵𝗼𝗿𝘀: Shuaiyi Li, Yiping Liu, Bao Yang, Zetong Zhu, Licheng Zhou, Zhenyu Jiang, Zejia Liu, Liqun Tang, and Xiulan Zou

𝗦𝘂𝗯𝗺𝗶𝘁 𝘆𝗼𝘂𝗿 𝗺𝗮𝗻𝘂𝘀𝗰𝗿𝗶𝗽𝘁: link.springer.com/journal/10439

Doctors need detailed information about blood circulation to manage complex heart conditions, but obtaining it can require extensive clinical testing and computational analysis.

To make this process faster and more practical, researchers compared three neural network approaches ow and pressure across a 17-vessel arterial network. They incorporated physical laws to improve predictive accuracy and integrated the best-performing approach with a Bayesian statistical framework. Using MRI measurements from two patients with Fontan circulation, the model reproduced measured blood flow waveforms and estimated blood pressure consistent with cuff measurements while quantifying uncertainty.

By making cardiovascular assessments more computationally accessible, this approach could improve the efficiency of clinical evaluations while providing additional physiological information to guide decisions about disease management and future interventions.

𝗥𝗲𝗮𝗱 𝗺𝗼𝗿𝗲: link.springer.com/article/10.100…

𝗦𝘁𝘂𝗱𝘆: Physics-Informed Neural Operators for Parameter Inference in Multi-vessel Cardiovascular Networks

𝗔𝘂𝘁𝗵𝗼𝗿𝘀: William Ryan, Alyssa Taylor-LaPole, Mette S. Olufsen, Vladislav Vyshemirsky, and Dirk Husmeier

@UofGlasgow
@NCState
@NCStateSciences
@NCState_Math

𝗦𝘂𝗯𝗺𝗶𝘁 𝘆𝗼𝘂𝗿 𝗺𝗮𝗻𝘂𝘀𝗰𝗿𝗶𝗽𝘁: link.springer.com/journal/10439

Traditional measures of skating performance may overlook important differences in how hockey and figure skaters coordinate their movements, limiting the ability to assess proficiency and identify areas for improvement.

Researchers evaluated whether wearable sensors could provide cture of skating biomechanics by measuring 19 hockey and figure skaters during maximum-speed sprints. Six sensors captured conventional performance metrics alongside more detailed indicators of movement complexity, coordination between limbs, and joint motion. The analysis revealed differences associated with athletic proficiency and discipline, while most sensor-derived measures showed little correlation with vertical jump height, suggesting that conventional off-ice testing may not adequately reflect on-ice performance.

These findings could inform the development of more sport-specific assessments, enabling coaches and rehabilitation specialists to better characterize movement patterns and potentially guide personalized training and return-to-sport evaluations.

𝗥𝗲𝗮𝗱 𝗺𝗼𝗿𝗲: link.springer.com/article/10.100…

𝗦𝘁𝘂𝗱𝘆: A Novel Approach to Assessing Ice Skating Sprint Performance Using Wearable Sensors

𝗔𝘂𝘁𝗵𝗼𝗿𝘀: Aminreza Khandan, Ramin Fathian, Loren ZF Chiu, Jason P. Carey, and Hossein Rouhani

@UAlberta
@UAlberta_Eng
@UAlbertaKSR
@fathian_ramin

𝗦𝘂𝗯𝗺𝗶𝘁 𝘆𝗼𝘂𝗿 𝗺𝗮𝗻𝘂𝘀𝗰𝗿𝗶𝗽𝘁: link.springer.com/journal/10439

Low back disorders disproportionately affect women and older adults for reasons that remain poorly understood.

Researchers examined the role of spinal anatomy in these disparities by developing 360 subject-specific computational models of lumbar spine segments using CT scans five decades of age. The models isolated the effects of vertebral geometry on how forces are distributed across intervertebral discs and facet joints under seven loading conditions. The findings revealed substantial differences associated with sex and age, including higher facet joint forces and shear loads in older adults and up to 31% greater disc loading relative to vertebral endplate area in women compared with men.

An anatomically informed understanding of spinal biomechanics could help clinicians better assess mechanical vulnerability, potentially guiding earlier interventions and more targeted strategies for reducing the risk of low back disorders.

𝗥𝗲𝗮𝗱 𝗺𝗼𝗿𝗲: link.springer.com/article/10.100…

𝗦𝘁𝘂𝗱𝘆: Sex- and Age-Related Variation in Vertebral Geometry Influences Lumbar Spine Loading: An Image-Based Computational Modeling Study

𝗔𝘂𝘁𝗵𝗼𝗿𝘀: Gregory G. Knapik, Ehud Mendel, Eric Bourekas, and William S. Marras

@OhioState
@OhioStateMed
@Yale
@YaleMed
@YNeurosurgery

𝗦𝘂𝗯𝗺𝗶𝘁 𝘆𝗼𝘂𝗿 𝗺𝗮𝗻𝘂𝘀𝗰𝗿𝗶𝗽𝘁: link.springer.com/journal/10439

Fighter pilots face an elevated risk of neck pain from the weight of their helmets, raising questions about how the added strain affects the muscles and structures of the cervical spine.

To investigate these effects, researchers used a validated cervical spine model to compare ing the forces needed to stabilize the head with and without a helmet.

The methods produced different muscle activation patterns, with one preferentially recruiting larger muscles and shear wave elastography showing greater activation of deep stabilizers. The latter approach also aligned more closely with in vivo electromyography data, while both methods produced physiologically plausible spinal loads in the no-helmet condition.

Refining estimates of cervical muscle forces could improve predictions of pain mechanisms and inform safer helmet designs, injury prevention strategies, and individualized rehabilitation.

𝗥𝗲𝗮𝗱 𝗺𝗼𝗿𝗲: link.springer.com/article/10.100…

𝗦𝘁𝘂𝗱𝘆: Predicting Cervical Muscle Forces in Fighter Pilots: A Comparison of Shear Wave Elastography and PID Controllers Using Finite Element Analysis

𝗔𝘂𝘁𝗵𝗼𝗿𝘀: Mackenzie Hoey, Constantin Heinemann, Alex Vadati, and Zachary J. Domire

@EastCarolina

𝗦𝘂𝗯𝗺𝗶𝘁 𝘆𝗼𝘂𝗿 𝗺𝗮𝗻𝘂𝘀𝗰𝗿𝗶𝗽𝘁: link.springer.com/journal/10439

The potential for brain-computer interfaces to help people control assistive technologies is limited by variations in brain signals that make reliable performance across individuals difficult to achieve.

To reduce the impact of this variability, researchers created a deep gned to interpret brain signals associated with imagined movement without requiring models tailored to each person.

The approach aligns data to reduce physiological differences, identifies patterns in brain activity across multiple spatial and temporal scales, and uses an attention mechanism to emphasize the most informative signals. Tested on a public brain-computer interface dataset, the model achieved an average accuracy of 67.5% across previously unseen individuals, with accuracy for some individuals reaching 81.4% while using relatively few parameters.

Reducing reliance on person-specific training could make brain-controlled assistive technologies easier to deploy across a wider range of users.

𝗥𝗲𝗮𝗱 𝗺𝗼𝗿𝗲: link.springer.com/article/10.100…

𝗦𝘁𝘂𝗱𝘆: A Multiscale Decoding Approach of Subject-Independent Motor Imagery EEG Signal Combined with Data Alignment Strategy

𝗔𝘂𝘁𝗵𝗼𝗿𝘀: Jixiang Li, Yurong Li, Wuxiang Shi, Ranlan Kang, and Hongyan Wang

𝗦𝘂𝗯𝗺𝗶𝘁 𝘆𝗼𝘂𝗿 𝗺𝗮𝗻𝘂𝘀𝗰𝗿𝗶𝗽𝘁: link.springer.com/journal/10439

Corneal cross-linking, a treatment that strengthens weakened corneal tissue, can help stabilize the eye in people with keratoconus, but how an individual cornea will change after treatment is not always predictable.

Addressing this uncertainty, researchers built a element model that accounts for both the mechanical and geometrical changes caused by these procedures. Using measurements from donor corneas, they characterized changes in stiffness and viscoelasticity, then personalized models for three individuals with keratoconus using corneal topography and in vivo optical coherence elastography. As a proof of concept, the models predicted changes in corneal curvature that closely approximated clinical measurements six months after treatment.

The ability to reliably anticipate procedural outcomes could enhance clinical planning for cross-linking procedures, potentially refining control over post-treatment corneal shape and vision.

𝗥𝗲𝗮𝗱 𝗺𝗼𝗿𝗲: link.springer.com/article/10.100…

𝗦𝘁𝘂𝗱𝘆: Integration of Mechanical Testing, In Vivo Optical Coherence Elastography and Personalized Finite Element Modeling to Predict Geometrical Outcomes of Corneal Cross-Linking

𝗔𝘂𝘁𝗵𝗼𝗿𝘀: Matteo Frigelli, Robert Lohmüller, Miguel A. Ariza Gracia, Günther Schlunck, Stefan J. Lang, @ETorresNetto, @farhad_hafezi, Philippe Büchler, and Sabine Kling

@unibern

𝗦𝘂𝗯𝗺𝗶𝘁 𝘆𝗼𝘂𝗿 𝗺𝗮𝗻𝘂𝘀𝗰𝗿𝗶𝗽𝘁: link.springer.com/journal/10439

Before a donor meniscus reaches the operating room, the methods used to preserve it may compromise its ability to function as intended.

Researchers compared menisci tested immediately after collection with those kept for 21 days under fresh or frozen conditions to determine how heir structural and mechanical properties.

Both fresh storage and freezing increased tissue permeability and porosity while reducing measures of compressive mechanical performance compared with controls. Tissue frozen with a cryoprotectant showed intermediate structural and mechanical properties, suggesting that limiting ice formation may reduce preservation-related changes.

Evidence of how storage alters menisci could inform improved preservation guidelines, giving clinicians greater confidence in the quality of tissue selected for transplantation.

𝗥𝗲𝗮𝗱 𝗺𝗼𝗿𝗲: link.springer.com/article/10.100…

𝗦𝘁𝘂𝗱𝘆: Effects of Preservation on the Compressive Properties and Microstructure of the Knee Meniscus

𝗔𝘂𝘁𝗵𝗼𝗿𝘀: Chester Jar, Abbi Oguchi, Mohammadhamed Shahsavari, Nadr M. Jomha, Lindsey Westover, and Gail M. Thornton

@UAlberta
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𝗦𝘂𝗯𝗺𝗶𝘁 𝘆𝗼𝘂𝗿 𝗺𝗮𝗻𝘂𝘀𝗰𝗿𝗶𝗽𝘁: link.springer.com/journal/10439