We are delighted to share our collaborative work with Ibarra Lab @3M_Lab and Fernandez-Leiro Lab @rfleiro, in which we dissect autoregulatory mechanism of Twinkle helicase! Big thank you to Sjoerd Wanrooij @Wanrooij20 and other reviewers for a smooth process!
@Greg_Ciesielski ; nature.com/articles/s4146…

Excited to share our latest paper, published in Nature Communications!
As first author from @3M_Lab, I’m proud of this collaborative effort with @LabMito and @rfleiro, where we dissect the autoregulatory mechanism of the mitochondrial helicase Twinkle.
🔗 nature.com/articles/s4146…

Lamentamos que un medio como @elconfidencial donde escriben grandes periodistas, utilice una fuente inadecuada para informar del tiempo, haciendo pasar por meteorólogo a quien no lo es y fomentando el consumo de su contenido.
En esto, o eres parte del problema o de la solución

Estamos buscando con cierta urgencia candidatos con motivación e ilusión para solicitar un contrato predoctoral ligado a un proyecto de tesis doctoral en nuestro @GrupoBIOMIL, bien conectado con el mundo clínico y con el sector industrial.
Más información:
linkedin.com/posts/b%C3%A1r…

REGISTRATION OPEN - CNIO meeting, Machines acting on DNA and RNA, 2025 May 28-30th in Madrid, organized by @NogalesLab , @rfleiro , @LlorcaLab

Bringing leaders in structural biology in Chromatin structure, DNA repair, RNA processing, Replication, Transcription and Translation.

The #ESRWnano workshop will take place at @IMDEA_nano, but also online! Follow the hashtag #ESRWnano and check the posts in your favourite social media -all posts will be published in the website.

🟦🟩🟨🟧🟥 nanociencia.imdea.org/home-en/events…

Check out the fruits of our wonderful collaboration with @3M_Lab and @rfleiro, @Greg_Ciesielski.
Auto-regulation of the real-time kinetics of the human mitochondrial replicative helicase biorxiv.org/content/10.110…

@rfleiro @FundlaCaixa @CNIOStopCancer @3mlaboratory @IMDEA_nano @CIB_CSIC 🤝Este proyecto #CaixaResearch, liderado por @rfleiro, se realiza en consorcio con:

👉Borja Ibarra Urruela, de @IMDEA_nano
👉Cristina Ugalde Bilbao, de @CIB_CSIC

🧬Errores en la replicación del ADN de las mitocondrias —un componente celular— se asocian a trastornos neurodegenerativos como el alzhéimer y el párkinson.

Con una ayuda #CaixaResearch, @rfleiro investigará cómo contribuyen estos errores a las patologías, lo que permitirá ximaciones terapéuticas.

tinyurl.com/5n7etfrr

Researchers @IMDEA_Nano @CNB_CSIC @nanolsi @KanazawaUniv_O record the first "film" of the multiplication of the influenza A virus genome.

🎞️nanociencia.imdea.org/home-en/news/i…

1/4 #IMDEAnanoPublications #sciart @Scixel

Six days left to apply to SMB 2025 in Aspen, CO. Lots of great single molecule biophysics in a spectacular location.
For details on the meeting and the application process, see our web site: jila.colorado.edu/smb/

Please RT.
-Aaron and Tom

A fantastic lineup of speakers for the "Machines acting on DNA and RNA" meeting at @CNIOStopCancer

All things D/RNA! 🧬Replication + transcription + translation + chromatin + repair + processing🧬

May 28th to 30th, 2025 - Save the date!

@OscarLlorcaCNIO @rfleiro @NogalesLab

Super excited to share our latest work on the native in-cell organization of the mitochondrial respiratory chain 🥳
Using cryo-electron tomography🔬, we show how the respiratory complexes (and other complexes) are organized inside native mitochondria! 
biorxiv.org/content/10.110…

📢📢We are hiring!
We're looking for a Postdoctoral Research Assistant to explore the dynamics of human mitochondrial DNA replication at the single-molecule level @IMDEA_nano
Review the details below👇or visit borjaibarralab.com 💻
Please RT 🙏🙏

Researchers @IMDEA_nano @unistra led by @Hermanslab control -in real time- a chemical reaction network by light.

🔦nanociencia.imdea.org/home-en/news/i…

1/3 #IMDEAnanoPublications

Preprint alert from the lab!!! Huge congrats to the lead author Salina Quack and many thanks to our collaborators @yorgomodis, #WouterRoos, and @CBroedersz
biorxiv.org/content/10.110…
Buckle up for a long 🧵... 1/

Scientists from @nanolsi @KanazawaUniv_O @IMDEA_Nano use high-speed atomic force microscopy and electron microscopy to study the conformational dynamics of individual #InfluenzaAvirus recombinant RNPs (rRNPs) during #RNASynthesis. @3M_Lab

#OpenAccess: go.acs.org/afx

📢 Intrigued by #Influenza #virus and viral #transcription? Check our work on the real-time conformational dynamics of Influenza A RNPs during #RNA synthesis, observed through #HSAFM. Great collaboration between @CNB_CSIC @nanolsi @IMDEA_Nano
👇doi.org/10.1021/acsnan…

The first call deadline is fast approaching!
Apply until the 23rd of August to the @IDEALcofund PhD Fellowships in Nanoscience.

🗺️📍@imdea_nano, Madrid 🇪🇸

👇Read about some of the projects 👇 The offer is great!
idealcofund-project.eu/phd/phd-projec…